ID   PHYA_PEA                Reviewed;        1124 AA.
AC   P15001;
DT   01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1990, sequence version 1.
DT   03-AUG-2022, entry version 121.
DE   RecName: Full=Phytochrome A;
GN   Name=PHYA;
OS   Pisum sativum (Garden pea).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC   NPAAA clade; Hologalegina; IRL clade; Fabeae; Pisum.
OX   NCBI_TaxID=3888;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=cv. Alaska;
RX   AGRICOLA=IND92000014; DOI=10.1007/BF00017469;
RA   Sato N.;
RT   "Nucleotide sequence and expression of the phytochrome gene in Pisum
RT   sativum: differential regulation by light of multiple transcripts.";
RL   Plant Mol. Biol. 11:697-710(1988).
CC   -!- FUNCTION: Regulatory photoreceptor which exists in two forms that are
CC       reversibly interconvertible by light: the Pr form that absorbs
CC       maximally in the red region of the spectrum and the Pfr form that
CC       absorbs maximally in the far-red region. Photoconversion of Pr to Pfr
CC       induces an array of morphogenic responses, whereas reconversion of Pfr
CC       to Pr cancels the induction of those responses. Pfr controls the
CC       expression of a number of nuclear genes including those encoding the
CC       small subunit of ribulose-bisphosphate carboxylase, chlorophyll A/B
CC       binding protein, protochlorophyllide reductase, rRNA, etc. It also
CC       controls the expression of its own gene(s) in a negative feedback
CC       fashion.
CC   -!- SUBUNIT: Homodimer.
CC   -!- PTM: Contains one covalently linked phytochromobilin chromophore.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the phytochrome family. {ECO:0000305}.
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DR   EMBL; M37217; AAA33682.1; -; Genomic_DNA.
DR   EMBL; X14077; CAA32242.1; -; Genomic_DNA.
DR   PIR; S06856; S06856.
DR   AlphaFoldDB; P15001; -.
DR   SMR; P15001; -.
DR   EnsemblPlants; Psat6g156640.1; Psat6g156640.1.cds; Psat6g156640.
DR   Gramene; Psat6g156640.1; Psat6g156640.1.cds; Psat6g156640.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   GO; GO:0009881; F:photoreceptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR   GO; GO:0009584; P:detection of visible light; IEA:InterPro.
DR   GO; GO:0017006; P:protein-tetrapyrrole linkage; IEA:InterPro.
DR   GO; GO:0009585; P:red, far-red light phototransduction; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd00082; HisKA; 1.
DR   CDD; cd00130; PAS; 2.
DR   Gene3D; 3.30.450.270; -; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 3.30.565.10; -; 1.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR005467; His_kinase_dom.
DR   InterPro; IPR003661; HisK_dim/P.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013654; PAS_2.
DR   InterPro; IPR013767; PAS_fold.
DR   InterPro; IPR016132; Phyto_chromo_attachment.
DR   InterPro; IPR013516; Phyto_chromo_BS.
DR   InterPro; IPR001294; Phytochrome.
DR   InterPro; IPR012129; Phytochrome_A-E.
DR   InterPro; IPR013515; Phytochrome_cen-reg.
DR   InterPro; IPR043150; Phytochrome_PHY.
DR   Pfam; PF01590; GAF; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF00989; PAS; 2.
DR   Pfam; PF08446; PAS_2; 1.
DR   Pfam; PF00360; PHY; 1.
DR   PIRSF; PIRSF000084; Phytochrome; 1.
DR   PRINTS; PR01033; PHYTOCHROME.
DR   SMART; SM00065; GAF; 1.
DR   SMART; SM00387; HATPase_c; 1.
DR   SMART; SM00388; HisKA; 1.
DR   SMART; SM00091; PAS; 2.
DR   SUPFAM; SSF55785; SSF55785; 3.
DR   SUPFAM; SSF55874; SSF55874; 1.
DR   TIGRFAMs; TIGR00229; sensory_box; 1.
DR   PROSITE; PS50109; HIS_KIN; 1.
DR   PROSITE; PS50112; PAS; 2.
DR   PROSITE; PS00245; PHYTOCHROME_1; 1.
DR   PROSITE; PS50046; PHYTOCHROME_2; 1.
PE   3: Inferred from homology;
KW   Chromophore; Photoreceptor protein; Receptor; Repeat; Sensory transduction;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..1124
FT                   /note="Phytochrome A"
FT                   /id="PRO_0000171980"
FT   DOMAIN          218..401
FT                   /note="GAF"
FT   DOMAIN          617..687
FT                   /note="PAS 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00140"
FT   DOMAIN          750..821
FT                   /note="PAS 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00140"
FT   DOMAIN          901..1120
FT                   /note="Histidine kinase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00107"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         323
FT                   /ligand="phytochromobilin"
FT                   /ligand_id="ChEBI:CHEBI:189064"
FT                   /note="covalent, via 1 link"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   1124 AA;  124028 MW;  D94AD89F6AAF72ED CRC64;
     MSTTRPSQSS NNSGRSRNSA RIIAQTTVDA KLHATFEESG SSFDYSSSVR VSGSVDGDQQ
     PRSNKVTTAY LNHIQRGKQI QPFGCLLALD EKTCKVVAYS ENAPEMLTMV SHAVPSVGDH
     PALGIGTDIR TVFTAPSASA LQKALGFAEV SLLNPILVHC KTSGKPFYAI IHRVTGSLII
     DFEPVKPYEV PMTAAGALQS YKLAAKAITR LQSLASGSME RLCDTMVQEV FELTGYDRVM
     AYKFHEDDHG EVIAEIAKPG LEPYLGLHYP ATDIPQAARF LFMKNKVRMI VDCNAKHVKV
     LQDEKLPFDL TLCGSTLRAP HSCHLQYMAN MDSIASLVMA VVVNDSDEDG DSADAVLPQK
     KKRLWGLVVC HNTTPRFVPF PLRYACEFLA QVFAIHVNKE IELEYQILEK NILRTQTLLC
     DMLMRDAPLG IVSQSPNIMD LVKCDGAALF YRNKLWLLGA TPTESQLREI ALWMSEYHTD
     STGLSTDSLS DAGFPGALSL SDTVCGMAAV RITSKDIVFW FRSHTAAEIR WGGAKHEPGD
     QDDGRKMHPR SSFKAFLEVV KARSVPWKDF EMDAIHSLQL ILRNASKDTD IIDLNTKAIN
     TRLNDLKIEG MQELEAVTSE MVRLIETATV PILAVDVDGT VNGWNIKIAE LTGLPVGEAI
     GKHLLTLVED SSTDIVKKML NLALQGEEEK NVQFEIKTHG DQVESGPISL IVNACASKDL
     RENVVGVCFV AQDITAQKTV MDKFTRIEGD YKAIVQNPNQ LIPPIFGTDE FGWCCEWNAA
     MIKLTGWKRE EVMDKMLLGE VFGTQMSCCR LKNQEAFVNF GIVLNKAMTG LETEKVPFGF
     FSRKGKYVEC LLSVSKKIDA EGLVTGVFCF LQLASPELQQ ALHIQRLSEQ TALKRLKVLT
     YMKRQIRNPL AGIVFSSKML EGTDLETEQK RIVNTSSQCQ RQLSKILDDS DLDGIIDGYL
     DLEMAEFTLH EVLVTSLSQV MNRSNTKGIR IANDVAEHIA RETLYGDSLR LQQVLADFLL
     ISINSTPNGG QVVIAASLTK EQLGKSVHLV NLELSITHGG SGVPEAALNQ MFGNNVLESE
     EGISLHISRK LLKLMNGDVR YLKEAGKSSF ILSVELAAAH KLKG