ID   PHYA_SOLTU              Reviewed;        1123 AA.
AC   P30733;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1994, sequence version 2.
DT   03-AUG-2022, entry version 141.
DE   RecName: Full=Phytochrome A;
GN   Name=PHYA;
OS   Solanum tuberosum (Potato).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum.
OX   NCBI_TaxID=4113;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Desiree;
RX   PubMed=1536928; DOI=10.1007/bf00040669;
RA   Heyer A., Gatz C.;
RT   "Isolation and characterization of a cDNA-clone coding for potato type A
RT   phytochrome.";
RL   Plant Mol. Biol. 18:535-544(1992).
CC   -!- FUNCTION: Regulatory photoreceptor which exists in two forms that are
CC       reversibly interconvertible by light: the Pr form that absorbs
CC       maximally in the red region of the spectrum and the Pfr form that
CC       absorbs maximally in the far-red region. Photoconversion of Pr to Pfr
CC       induces an array of morphogenic responses, whereas reconversion of Pfr
CC       to Pr cancels the induction of those responses. Pfr controls the
CC       expression of a number of nuclear genes including those encoding the
CC       small subunit of ribulose-bisphosphate carboxylase, chlorophyll A/B
CC       binding protein, protochlorophyllide reductase, rRNA, etc. It also
CC       controls the expression of its own gene(s) in a negative feedback
CC       fashion.
CC   -!- SUBUNIT: Homodimer.
CC   -!- PTM: Contains one covalently linked phytochromobilin chromophore.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the phytochrome family. {ECO:0000305}.
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DR   EMBL; S84872; AAB21533.2; -; mRNA.
DR   PIR; S20497; S20497.
DR   AlphaFoldDB; P30733; -.
DR   SMR; P30733; -.
DR   IntAct; P30733; 9.
DR   STRING; 4113.PGSC0003DMT400040772; -.
DR   PRIDE; P30733; -.
DR   eggNOG; ENOG502QRSA; Eukaryota.
DR   InParanoid; P30733; -.
DR   Proteomes; UP000011115; Unassembled WGS sequence.
DR   ExpressionAtlas; P30733; baseline and differential.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   GO; GO:0009881; F:photoreceptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR   GO; GO:0009584; P:detection of visible light; IEA:InterPro.
DR   GO; GO:0017006; P:protein-tetrapyrrole linkage; IEA:InterPro.
DR   GO; GO:0009585; P:red, far-red light phototransduction; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd00082; HisKA; 1.
DR   CDD; cd00130; PAS; 2.
DR   Gene3D; 3.30.450.270; -; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 3.30.565.10; -; 1.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR005467; His_kinase_dom.
DR   InterPro; IPR003661; HisK_dim/P.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013654; PAS_2.
DR   InterPro; IPR013767; PAS_fold.
DR   InterPro; IPR016132; Phyto_chromo_attachment.
DR   InterPro; IPR013516; Phyto_chromo_BS.
DR   InterPro; IPR001294; Phytochrome.
DR   InterPro; IPR012129; Phytochrome_A-E.
DR   InterPro; IPR013515; Phytochrome_cen-reg.
DR   InterPro; IPR043150; Phytochrome_PHY.
DR   Pfam; PF01590; GAF; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF00512; HisKA; 1.
DR   Pfam; PF00989; PAS; 2.
DR   Pfam; PF08446; PAS_2; 1.
DR   Pfam; PF00360; PHY; 1.
DR   PIRSF; PIRSF000084; Phytochrome; 1.
DR   PRINTS; PR01033; PHYTOCHROME.
DR   SMART; SM00065; GAF; 1.
DR   SMART; SM00387; HATPase_c; 1.
DR   SMART; SM00388; HisKA; 1.
DR   SMART; SM00091; PAS; 2.
DR   SUPFAM; SSF55785; SSF55785; 3.
DR   SUPFAM; SSF55874; SSF55874; 1.
DR   TIGRFAMs; TIGR00229; sensory_box; 1.
DR   PROSITE; PS50109; HIS_KIN; 1.
DR   PROSITE; PS50113; PAC; 1.
DR   PROSITE; PS50112; PAS; 2.
DR   PROSITE; PS00245; PHYTOCHROME_1; 1.
DR   PROSITE; PS50046; PHYTOCHROME_2; 1.
PE   2: Evidence at transcript level;
KW   Chromophore; Photoreceptor protein; Receptor; Reference proteome; Repeat;
KW   Sensory transduction; Transcription; Transcription regulation.
FT   CHAIN           1..1123
FT                   /note="Phytochrome A"
FT                   /id="PRO_0000171992"
FT   DOMAIN          218..401
FT                   /note="GAF"
FT   DOMAIN          617..687
FT                   /note="PAS 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00140"
FT   DOMAIN          690..746
FT                   /note="PAC"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00141"
FT   DOMAIN          747..821
FT                   /note="PAS 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00140"
FT   DOMAIN          901..1118
FT                   /note="Histidine kinase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00107"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         323
FT                   /ligand="phytochromobilin"
FT                   /ligand_id="ChEBI:CHEBI:189064"
FT                   /note="covalent, via 1 link"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   1123 AA;  124690 MW;  3A97062A5DFB29EA CRC64;
     MSSSRPSQSS TTSSRSKHSA RIIAQTSIDA KLHADFEESG DSFDYSSSVR VTNVAEGEQR
     PKSDKVTTAY LHQIQKGKFI QPFGCLLALD EKTLKVIAFS ENAPEMLTMV SHAVPSVGEH
     PVLGIGIDIR TIFTGPSGAA LQKALGFGEV SLLNPVLVHC KNSGKPFYAI VHRVTGSLII
     DFEPVKPYEV PMTAAGALQS YKLAAKAITR LQSLPSGSME RLCDTMVQEV FELTGYDRVM
     GYKFHDDDHG EVVSEITKPG LEPYLGLHYP ATDIPQAARF LFMKNKVRMI CDCRAKHVKV
     VQDEKLPFDL TLCGSTLRAP HYCHLQYMEN MNSIASLVMA VVVNDGDEEG ESSDSSQSQK
     RKRLWGLVVS HNTTPRFAPF PLRYACEFLA QVFAILVNKE LELENQFLEK NILRTQTLLC
     DMLMRDAPLG IVSQSPNIMD LIKCDGAALL YKNKIHRLGM NPSDFQLHDI VSWLCEYHTD
     STGLSTDSLY DAGFPGALAL GDAVCGMAAV RISDKDWLFW YRSHTAAEVR WGGAKHEPGE
     KDDGRKMHPR SSFKGFLEVV KTRSIPWKDY EMDRIHSLQL ILRNAFKDAD AVNSNTISIH
     TKLNDLKIDG MQELEAVTAE MVRLIETASV PIFAVDVDGQ VNGWNTKVAE LTGLPVDEAI
     GKHLLTLVED SSVDTVNKML ELALQGQEER NVEFEIKTHG PSRDSSPISL IVNACASKDV
     RDSVVGVCFI AQDITGQKSI MDKFTRIEGD YRAIIQNPHP LIPPIFGTDQ FGWCSEWNSA
     MTMLTGWRRD DVMDKMLLGE VFGTQAACCR LKNQEAFVNF GVILNNAITG QESEKIPFGF
     FARYGKYVEC LLCVSKRLDK EGAVTGLFCF LQLASHELQQ ALHVQRLSEQ TALKRLKVLA
     YIRRQIRNPL SGIIFSRKML EGTSLGEEQK NILHTSAQCQ RQLDKILDDT DLDSIIEGYL
     DLEMLEFKLH EVLVASISQV MMKSNGKNIM ISNDMVEDLL NETLYGDSPR LQQVLANFLL
     VSVNSTPSGG KLSISGKLTK DRIGESVQLA LLEFRIRHTG GGVPEELLSQ MFGSEADASE
     EGISLLVSRK LVKLMNGEVQ YLREAGRSTF IISVELAVAT KSS