ID   PHYA_SORBI              Reviewed;        1131 AA.
AC   P93526;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1997, sequence version 1.
DT   03-AUG-2022, entry version 136.
DE   RecName: Full=Phytochrome a;
GN   Name=PHYA; OrderedLocusNames=Sb03g017600;
OS   Sorghum bicolor (Sorghum) (Sorghum vulgare).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Sorghinae; Sorghum.
OX   NCBI_TaxID=4558;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=9046599; DOI=10.1104/pp.113.2.611;
RA   Childs K.L., Miller F.R., Cordonnier-Pratt M.-M., Pratt L.H., Morgan P.W.,
RA   Mullet J.E.;
RT   "The Sorghum bicolor photoperiod sensitivity gene, Ma3, encodes a
RT   phytochrome B.";
RL   Plant Physiol. 113:611-619(1997).
CC   -!- FUNCTION: Regulatory photoreceptor which exists in two forms that are
CC       reversibly interconvertible by light: the Pr form that absorbs
CC       maximally in the red region of the spectrum and the Pfr form that
CC       absorbs maximally in the far-red region. Photoconversion of Pr to Pfr
CC       induces an array of morphogenic responses, whereas reconversion of Pfr
CC       to Pr cancels the induction of those responses. Pfr controls the
CC       expression of a number of nuclear genes including those encoding the
CC       small subunit of ribulose-bisphosphate carboxylase, chlorophyll A/B
CC       binding protein, protochlorophyllide reductase, rRNA, etc. It also
CC       controls the expression of its own gene(s) in a negative feedback
CC       fashion (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- PTM: Contains one covalently linked phytochromobilin chromophore.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the phytochrome family. {ECO:0000305}.
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DR   EMBL; U56729; AAB41397.1; -; mRNA.
DR   AlphaFoldDB; P93526; -.
DR   SMR; P93526; -.
DR   STRING; 4558.Sb01g009920.2; -.
DR   eggNOG; ENOG502QRSA; Eukaryota.
DR   HOGENOM; CLU_010418_0_0_1; -.
DR   ExpressionAtlas; P93526; baseline and differential.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   GO; GO:0009881; F:photoreceptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR   GO; GO:0009584; P:detection of visible light; IEA:InterPro.
DR   GO; GO:0017006; P:protein-tetrapyrrole linkage; IEA:InterPro.
DR   GO; GO:0009585; P:red, far-red light phototransduction; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd00082; HisKA; 1.
DR   CDD; cd00130; PAS; 2.
DR   Gene3D; 3.30.450.270; -; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 3.30.565.10; -; 1.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR005467; His_kinase_dom.
DR   InterPro; IPR003661; HisK_dim/P.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013654; PAS_2.
DR   InterPro; IPR013767; PAS_fold.
DR   InterPro; IPR016132; Phyto_chromo_attachment.
DR   InterPro; IPR013516; Phyto_chromo_BS.
DR   InterPro; IPR001294; Phytochrome.
DR   InterPro; IPR012129; Phytochrome_A-E.
DR   InterPro; IPR013515; Phytochrome_cen-reg.
DR   InterPro; IPR043150; Phytochrome_PHY.
DR   Pfam; PF01590; GAF; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF00512; HisKA; 1.
DR   Pfam; PF00989; PAS; 2.
DR   Pfam; PF08446; PAS_2; 1.
DR   Pfam; PF00360; PHY; 1.
DR   PIRSF; PIRSF000084; Phytochrome; 1.
DR   PRINTS; PR01033; PHYTOCHROME.
DR   SMART; SM00065; GAF; 1.
DR   SMART; SM00387; HATPase_c; 1.
DR   SMART; SM00388; HisKA; 1.
DR   SMART; SM00091; PAS; 2.
DR   SUPFAM; SSF55785; SSF55785; 3.
DR   SUPFAM; SSF55874; SSF55874; 1.
DR   TIGRFAMs; TIGR00229; sensory_box; 1.
DR   PROSITE; PS50109; HIS_KIN; 1.
DR   PROSITE; PS50112; PAS; 2.
DR   PROSITE; PS00245; PHYTOCHROME_1; 1.
DR   PROSITE; PS50046; PHYTOCHROME_2; 1.
PE   2: Evidence at transcript level;
KW   Chromophore; Photoreceptor protein; Receptor; Repeat; Sensory transduction;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..1131
FT                   /note="Phytochrome a"
FT                   /id="PRO_0000171987"
FT   DOMAIN          219..404
FT                   /note="GAF"
FT   DOMAIN          620..690
FT                   /note="PAS 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00140"
FT   DOMAIN          750..834
FT                   /note="PAS 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00140"
FT   DOMAIN          904..1124
FT                   /note="Histidine kinase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00107"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         324
FT                   /ligand="phytochromobilin"
FT                   /ligand_id="ChEBI:CHEBI:189064"
FT                   /note="covalent, via 1 link"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   1131 AA;  125049 MW;  90E174FC6CD31C5D CRC64;
     MSSSRPAHSS SSSSRTRQSS QARILAQTTL DAELNAEYEE SGDSFDYSKL VEAQRSTPSE
     QQGRSGKVIA YLQHIQRGKL IQPFGCLLAL DEKSFRVIAF SENAPEMLTT VSHAVPNVDD
     PPKLGIGTNV RSLFTDPGAT ALQKALGFAD VSLLNPILVQ CKTSGKPFYA IVHRATGCLV
     VDFEPVKPTE FPATAAGALQ SYKLAAKAIS KIQSLPGGSM EALCNTVVKE VFELTGYDRV
     MAYKFHEDEH GEVFAEITKP GIEPYLGLHY PATDIPQAAR FLFMKNKVRM ICDCRAKSVK
     IIEDEALSID ISLCGSTLRA PHSCHLQYME NMNSIASLVM AVVVNENEED DEPGPEQPPQ
     QQKKKRLWGL IVCHHESPRY VPFPLRYACE FLAQVFAVHV NKEFELEKQI REKSILRMQT
     MLSDMLFKEA SPLSIVSGSP NIMDLVKCDG AALLYGDKVW RLQTAPTESQ IRDIAFWLSE
     VHGDSTGLST DSLQDAGYPG AASLGDMICG MAVAKITSKD ILFWFRSHTA AEIKWGGAKH
     DPSDKDDNRR MHPRLSFKAF LEVVKMKSLP WSDYEMDAIH SLQLILRGTL NDALKPVQAS
     GLDNQIGDLK LDGLAELQAV TSEMVRLMET ATVPILAVDG NGLVNGWNQK VAELSGLRVD
     EAIGRHILTL VEDSSVSIVQ RMLYLALQGK EEKEVRFELK THGSKRDDGP VILVVNACAS
     RDLHDHVVGV CFVAQDMTVH KLVMDKFTRV EGDYKAIIHN PNPLIPPIFG ADQFGWCSEW
     NVAMTKLTGW HRDEVIDKML LGEVFDSSNA SCLLKSKDDF VRLCIIINSA LAGEEAENAP
     FGLFDRNGKY IECLLSVNRK VNADGVVTGV FCFIHVPSDD LQHALHVQQA SEQTAQRRLK
     AFSYMRHAIN KPLSGMLYSR ETLKSTGLNE EQMRQVHVAD SCHRQLNKIL ADLDQDNITD
     KSSCLDLDMA EFVLEDVVVS AVSQVLIGCQ GKGIRVACNL PERFMKQKVY GDGIRLQQIL
     SDFLFVSVKF SPVGGSVDIS SKLTKNSIGE NLHLIDFELR IKHQGAGVPA EILSQMYEED
     NKEPSEEGLS LLVSRNLLRL MNGNIRHIRE AGMSTFILTA ELAAAPSAVG Q