ID   PHYB_NOSS1              Reviewed;         751 AA.
AC   Q9R6X3;
DT   11-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   03-AUG-2022, entry version 140.
DE   RecName: Full=Cyanobacterial phytochrome B;
DE            EC=2.7.13.3;
GN   Name=bphB; OrderedLocusNames=all2899;
OS   Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576).
OC   Bacteria; Cyanobacteria; Nostocales; Nostocaceae; Nostoc.
OX   NCBI_TaxID=103690;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Kamiya A., Kasahara M., Ohmori M.;
RT   "aphB, phytochrome-like gene of Anabaena 7120.";
RL   Submitted (NOV-1999) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 7120 / SAG 25.82 / UTEX 2576;
RX   PubMed=11759840; DOI=10.1093/dnares/8.5.205;
RA   Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A.,
RA   Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M.,
RA   Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M.,
RA   Takazawa M., Yamada M., Yasuda M., Tabata S.;
RT   "Complete genomic sequence of the filamentous nitrogen-fixing
RT   cyanobacterium Anabaena sp. strain PCC 7120.";
RL   DNA Res. 8:205-213(2001).
CC   -!- FUNCTION: Photoreceptor which exists in two forms that are reversibly
CC       interconvertible by light: the R form that absorbs maximally in the red
CC       region of the spectrum and the FR form that absorbs maximally in the
CC       far-red region. {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC         histidine.; EC=2.7.13.3;
CC   -!- PTM: Contains one covalently linked tetrapyrrole chromophore.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: In the N-terminal section; belongs to the phytochrome
CC       family. {ECO:0000305}.
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DR   EMBL; AB034952; BAA88060.1; -; Genomic_DNA.
DR   EMBL; BA000019; BAB74598.1; -; Genomic_DNA.
DR   PIR; AD2168; AD2168.
DR   RefSeq; WP_010997050.1; NZ_RSCN01000003.1.
DR   AlphaFoldDB; Q9R6X3; -.
DR   SMR; Q9R6X3; -.
DR   STRING; 103690.17131993; -.
DR   EnsemblBacteria; BAB74598; BAB74598; BAB74598.
DR   KEGG; ana:all2899; -.
DR   eggNOG; COG4251; Bacteria.
DR   OMA; YMRNIGM; -.
DR   OrthoDB; 1635706at2; -.
DR   BRENDA; 2.7.13.3; 319.
DR   Proteomes; UP000002483; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   GO; GO:0009881; F:photoreceptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0009584; P:detection of visible light; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd00082; HisKA; 1.
DR   Gene3D; 3.30.450.270; -; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 3.30.565.10; -; 1.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR005467; His_kinase_dom.
DR   InterPro; IPR003661; HisK_dim/P.
DR   InterPro; IPR036097; HisK_dim/P_sf.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013654; PAS_2.
DR   InterPro; IPR016132; Phyto_chromo_attachment.
DR   InterPro; IPR001294; Phytochrome.
DR   InterPro; IPR013515; Phytochrome_cen-reg.
DR   InterPro; IPR043150; Phytochrome_PHY.
DR   Pfam; PF01590; GAF; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF00512; HisKA; 1.
DR   Pfam; PF08446; PAS_2; 1.
DR   Pfam; PF00360; PHY; 1.
DR   PRINTS; PR01033; PHYTOCHROME.
DR   SMART; SM00065; GAF; 1.
DR   SMART; SM00387; HATPase_c; 1.
DR   SMART; SM00388; HisKA; 1.
DR   SUPFAM; SSF47384; SSF47384; 1.
DR   SUPFAM; SSF55785; SSF55785; 1.
DR   SUPFAM; SSF55874; SSF55874; 1.
DR   PROSITE; PS50109; HIS_KIN; 1.
DR   PROSITE; PS50046; PHYTOCHROME_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chromophore; Kinase; Nucleotide-binding; Phosphoprotein;
KW   Photoreceptor protein; Receptor; Reference proteome; Sensory transduction;
KW   Transcription; Transcription regulation; Transferase.
FT   CHAIN           1..751
FT                   /note="Cyanobacterial phytochrome B"
FT                   /id="PRO_0000171998"
FT   DOMAIN          152..320
FT                   /note="GAF"
FT   DOMAIN          536..751
FT                   /note="Histidine kinase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00107"
FT   REGION          22..511
FT                   /note="Chromophore binding domain"
FT   BINDING         17
FT                   /ligand="a tetrapyrrole"
FT                   /ligand_id="ChEBI:CHEBI:26932"
FT                   /note="covalent, via 1 link"
FT                   /evidence="ECO:0000250"
FT   MOD_RES         539
FT                   /note="Phosphohistidine; by autocatalysis"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00107"
SQ   SEQUENCE   751 AA;  85307 MW;  AFB899A24AB37ACB CRC64;
     MNINDITIPF QVDLSNCSKE PIHIPGLIQP HGVLLVLQEV DLTILQVSNN TFNILGRHPE
     QLLNQHLSCL LEAEQLSLLK DCLAQEDLQI INPLEFIIKS HNESISFDVI AHRSNNLLIL
     ELEANLSDKT HSFFRFYHLV KLAMLKLQGT ATTTEISQIL AQEVRKITGF DRVMVYRFDE
     QWNGKVIAEV KPEYLTSYLG LNYPASDIPQ QARKLYSQNW LRLIPDAKYQ PVPIVPINNP
     LNDQPLDLSR SVLRSVSPLH IEYMQNMGVT ASMSISIMKN QKLWGLIACH HQSPKYIPYE
     IRSACEFLGQ MTSVEMSAKE DSEDTEDKIQ VKSVHSKLVQ YMSAENDFIN ALIDHQPNIL
     DLVKAQGAAV CFNGNSCTVG QVPPMPDIQV LVEWMSQNIH EEIFATDSLA TVYPDAEKLR
     DVASGLIALS ISRSQKNYIL WFRPEVVRTV DWGGNPHKPV EVIANGEIRL SPRKSFDLWK
     ETVLLKSQPW KSHEVNAALE LRSAIIGIVL QKADELAQLN IELERSNQEL DAFAYIASHD
     LKEPLRGIHN YSNFLMEDYG EIIDAPGKEK LLTLIRLTQR MEDLIDSLLH FSRLGRVDLS
     MQDTDLNEIV HRILDMLSGR IEETGVEIRI LQLLPVVYCD RIQIGEVFSN LIANSIKYND
     KANKWIEIGY IDNPPLPPTF YVRDNGIGIR EKHFETIFRI FKRLHSPSKY GGGTGAGLTI
     AKKIVERHGG KIWVESTYGE GSTFYFTLQD V