ID   A57_VACCW               Reviewed;         151 AA.
AC   Q01230; Q80HT8;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   27-JUL-2011, sequence version 3.
DT   03-AUG-2022, entry version 77.
DE   RecName: Full=Guanylate kinase homolog;
GN   OrderedLocusNames=VACWR182; ORFNames=A57R;
OS   Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain
OS   WR)).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus; Vaccinia virus.
OX   NCBI_TaxID=10254;
OH   NCBI_TaxID=9913; Bos taurus (Bovine).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2045793; DOI=10.1099/0022-1317-72-6-1349;
RA   Smith G.L., Chan Y.S., Howard S.T.;
RT   "Nucleotide sequence of 42 kbp of vaccinia virus strain WR from near the
RT   right inverted terminal repeat.";
RL   J. Gen. Virol. 72:1349-1376(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Esposito J.J., Frace A.M., Sammons S.A., Olsen-Rasmussen M., Osborne J.,
RA   Wohlhueter R.;
RT   "Sequencing of the coding region of Vaccinia-WR to an average 9-fold
RT   redundancy and an error rate of 0.16/10kb.";
RL   Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the guanylate kinase family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; D11079; BAA01830.1; -; Genomic_DNA.
DR   EMBL; AY243312; AAO89461.1; -; Genomic_DNA.
DR   PIR; JQ1794; JQ1794.
DR   RefSeq; YP_233064.1; NC_006998.1.
DR   SMR; Q01230; -.
DR   DNASU; 3707653; -.
DR   GeneID; 3707653; -.
DR   KEGG; vg:3707653; -.
DR   Proteomes; UP000000344; Genome.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR008145; GK/Ca_channel_bsu.
DR   InterPro; IPR008144; Guanylate_kin-like_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00625; Guanylate_kin; 1.
DR   SMART; SM00072; GuKc; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS50052; GUANYLATE_KINASE_2; 1.
PE   3: Inferred from homology;
KW   Kinase; Reference proteome; Transferase.
FT   CHAIN           1..151
FT                   /note="Guanylate kinase homolog"
FT                   /id="PRO_0000170657"
FT   DOMAIN          1..141
FT                   /note="Guanylate kinase-like"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00100"
SQ   SEQUENCE   151 AA;  17414 MW;  8F604BDA76D83F6A CRC64;
     MEREGVDYHY VNREAIWKGI AAGNFLEHTE FLGNIYGTSK TAVNTAAINN RICVMDLNID
     GVRSLKNTYL MPYSVYIRPT SLKMVETKLR CRNTEANDEI HRRVILAKTD MDEANEAGLF
     DTIIIEDDVN LAYSKLIQIL QDRIRMYFNT N