ID   PHYD1_CAEBR             Reviewed;         288 AA.
AC   P0C660; A8WMU1;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-FEB-2008, sequence version 1.
DT   03-AUG-2022, entry version 65.
DE   RecName: Full=Phytanoyl-CoA dioxygenase domain-containing protein 1 homolog;
DE            EC=1.-.-.-;
GN   ORFNames=CBG00325;
OS   Caenorhabditis briggsae.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6238;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF16;
RX   PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA   Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA   Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA   Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA   Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA   Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA   Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA   Durbin R.M., Waterston R.H.;
RT   "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT   genomics.";
RL   PLoS Biol. 1:166-192(2003).
CC   -!- FUNCTION: Has alpha-ketoglutarate-dependent dioxygenase activity. Does
CC       not show detectable activity towards fatty acid CoA thioesters. Is not
CC       expected to be active with phytanoyl CoA (By similarity).
CC       {ECO:0000250}.
CC   -!- COFACTOR:
CC       Name=Fe cation; Xref=ChEBI:CHEBI:24875; Evidence={ECO:0000250};
CC   -!- SIMILARITY: Belongs to the PhyH family. PHYHD1 subfamily.
CC       {ECO:0000305}.
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DR   EMBL; HE600968; CAP21796.1; -; Genomic_DNA.
DR   RefSeq; XP_002632320.1; XM_002632274.1.
DR   AlphaFoldDB; P0C660; -.
DR   SMR; P0C660; -.
DR   STRING; 6238.CBG00325; -.
DR   EnsemblMetazoa; CBG00325.1; CBG00325.1; WBGene00023733.
DR   GeneID; 8574317; -.
DR   KEGG; cbr:CBG_00325; -.
DR   CTD; 8574317; -.
DR   WormBase; CBG00325; CBP05721; WBGene00023733; -.
DR   eggNOG; KOG3290; Eukaryota.
DR   HOGENOM; CLU_048953_0_0_1; -.
DR   InParanoid; P0C660; -.
DR   OMA; KYSEDNW; -.
DR   OrthoDB; 1316775at2759; -.
DR   Proteomes; UP000008549; Chromosome IV.
DR   GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR008775; Phytyl_CoA_dOase.
DR   Pfam; PF05721; PhyH; 1.
PE   3: Inferred from homology;
KW   Dioxygenase; Iron; Metal-binding; Oxidoreductase; Reference proteome.
FT   CHAIN           1..288
FT                   /note="Phytanoyl-CoA dioxygenase domain-containing protein
FT                   1 homolog"
FT                   /id="PRO_0000313637"
FT   BINDING         95
FT                   /ligand="2-oxoglutarate"
FT                   /ligand_id="ChEBI:CHEBI:16810"
FT                   /evidence="ECO:0000250"
FT   BINDING         134
FT                   /ligand="2-oxoglutarate"
FT                   /ligand_id="ChEBI:CHEBI:16810"
FT                   /evidence="ECO:0000250"
FT   BINDING         149..151
FT                   /ligand="2-oxoglutarate"
FT                   /ligand_id="ChEBI:CHEBI:16810"
FT                   /evidence="ECO:0000250"
FT   BINDING         149
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /evidence="ECO:0000250"
FT   BINDING         151
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /evidence="ECO:0000250"
FT   BINDING         167
FT                   /ligand="2-oxoglutarate"
FT                   /ligand_id="ChEBI:CHEBI:16810"
FT                   /evidence="ECO:0000250"
FT   BINDING         242
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /evidence="ECO:0000250"
FT   BINDING         244
FT                   /ligand="2-oxoglutarate"
FT                   /ligand_id="ChEBI:CHEBI:16810"
FT                   /evidence="ECO:0000250"
FT   BINDING         253
FT                   /ligand="2-oxoglutarate"
FT                   /ligand_id="ChEBI:CHEBI:16810"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   288 AA;  32833 MW;  CE962159F24B2635 CRC64;
     MSDLRQNFER DGFVVIENVF NDQEIEEIKG AIGKIVEDMN LAEHPKSVFS TYDEDKHAAD
     SYFLNSSDKI RFFFEEGAVD KDGELTVPKD KALNKIGHGL HLLDPTFKKM TFNSKIQKIF
     QGIGYQEPEV VQSMYIFKQP KIGGAVTDHV DSTFLRVNPI DHLTGVWIAI DEASVENGCL
     SFIPGSHKDT STSDYRFVRT HDTTGGPLLK FIGTRPTYDQ SKFQHVPISK GSLILIHGLV
     VHKSEANTSD KSRHAYTIHV MEKQNTEWSK DNWLQETEQY KFPNLYKQ