ID   PHYD1_CAEEL             Reviewed;         288 AA.
AC   Q9NAM7;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Phytanoyl-CoA dioxygenase domain-containing protein 1 homolog;
DE            EC=1.-.-.-;
GN   ORFNames=Y105C5B.9;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- FUNCTION: Has alpha-ketoglutarate-dependent dioxygenase activity. Does
CC       not show detectable activity towards fatty acid CoA thioesters. Is not
CC       expected to be active with phytanoyl CoA (By similarity).
CC       {ECO:0000250}.
CC   -!- COFACTOR:
CC       Name=Fe cation; Xref=ChEBI:CHEBI:24875; Evidence={ECO:0000250};
CC   -!- SIMILARITY: Belongs to the PhyH family. PHYHD1 subfamily.
CC       {ECO:0000305}.
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DR   EMBL; AL110479; CAB54355.1; -; Genomic_DNA.
DR   PIR; T26383; T26383.
DR   RefSeq; NP_502898.1; NM_070497.1.
DR   AlphaFoldDB; Q9NAM7; -.
DR   SMR; Q9NAM7; -.
DR   BioGRID; 43523; 2.
DR   STRING; 6239.Y105C5B.9; -.
DR   EPD; Q9NAM7; -.
DR   PaxDb; Q9NAM7; -.
DR   PeptideAtlas; Q9NAM7; -.
DR   EnsemblMetazoa; Y105C5B.9.1; Y105C5B.9.1; WBGene00013650.
DR   GeneID; 178445; -.
DR   KEGG; cel:CELE_Y105C5B.9; -.
DR   UCSC; Y105C5B.9; c. elegans.
DR   CTD; 178445; -.
DR   WormBase; Y105C5B.9; CE24085; WBGene00013650; -.
DR   eggNOG; KOG3290; Eukaryota.
DR   GeneTree; ENSGT00390000006287; -.
DR   HOGENOM; CLU_048953_0_0_1; -.
DR   InParanoid; Q9NAM7; -.
DR   OMA; KYSEDNW; -.
DR   OrthoDB; 1316775at2759; -.
DR   PhylomeDB; Q9NAM7; -.
DR   PRO; PR:Q9NAM7; -.
DR   Proteomes; UP000001940; Chromosome IV.
DR   Bgee; WBGene00013650; Expressed in embryo and 3 other tissues.
DR   GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR008775; Phytyl_CoA_dOase.
DR   Pfam; PF05721; PhyH; 1.
PE   3: Inferred from homology;
KW   Dioxygenase; Iron; Metal-binding; Oxidoreductase; Reference proteome.
FT   CHAIN           1..288
FT                   /note="Phytanoyl-CoA dioxygenase domain-containing protein
FT                   1 homolog"
FT                   /id="PRO_0000313638"
FT   BINDING         95
FT                   /ligand="2-oxoglutarate"
FT                   /ligand_id="ChEBI:CHEBI:16810"
FT                   /evidence="ECO:0000250"
FT   BINDING         134
FT                   /ligand="2-oxoglutarate"
FT                   /ligand_id="ChEBI:CHEBI:16810"
FT                   /evidence="ECO:0000250"
FT   BINDING         149..151
FT                   /ligand="2-oxoglutarate"
FT                   /ligand_id="ChEBI:CHEBI:16810"
FT                   /evidence="ECO:0000250"
FT   BINDING         149
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /evidence="ECO:0000250"
FT   BINDING         151
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /evidence="ECO:0000250"
FT   BINDING         167
FT                   /ligand="2-oxoglutarate"
FT                   /ligand_id="ChEBI:CHEBI:16810"
FT                   /evidence="ECO:0000250"
FT   BINDING         242
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /evidence="ECO:0000250"
FT   BINDING         244
FT                   /ligand="2-oxoglutarate"
FT                   /ligand_id="ChEBI:CHEBI:16810"
FT                   /evidence="ECO:0000250"
FT   BINDING         253
FT                   /ligand="2-oxoglutarate"
FT                   /ligand_id="ChEBI:CHEBI:16810"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   288 AA;  33020 MW;  2AEBCE889408AAC7 CRC64;
     MWDLREKFER DGFVVVENVF NDQEIDEMKK SISKIVNDMD LAEHPKSVFS TYDEDKHAAD
     SYFLNSSDKI RFFFEEGAVD KDGELTVPKD KALNKIGHGL HFLDPTFEKM TFNSKIQNIF
     KEIGYQEPGV VQSMYIFKQP KIGGAVTDHV DSTFLRVDPI DHLTGVWIAI DEASVENGCL
     SFIPGSHKDT SSANYRFVRT HDTSGGALLK FIGTRPTYDQ SKFQHVPISK GSLILIHGLV
     VHKSEANTSE KSRHAYTIHV MERKNTKWSE QNWLQETENY KFPDLYKD