PHYIP_BOVIN
ID PHYIP_BOVIN Reviewed; 330 AA.
AC Q0VD34;
DT 01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 05-SEP-2006, sequence version 1.
DT 03-AUG-2022, entry version 79.
DE RecName: Full=Phytanoyl-CoA hydroxylase-interacting protein;
DE AltName: Full=Phytanoyl-CoA hydroxylase-associated protein 1;
DE Short=PAHX-AP1;
DE Short=PAHXAP1;
GN Name=PHYHIP;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Thalamus;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Its interaction with PHYH suggests a role in the development
CC of the central system. {ECO:0000250}.
CC -!- SUBUNIT: Interacts with PHYH and ADGRB1. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the PHYHIP family. {ECO:0000305}.
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DR EMBL; BC119858; AAI19859.1; -; mRNA.
DR RefSeq; NP_001069883.1; NM_001076415.1.
DR AlphaFoldDB; Q0VD34; -.
DR SMR; Q0VD34; -.
DR STRING; 9913.ENSBTAP00000020921; -.
DR PaxDb; Q0VD34; -.
DR Ensembl; ENSBTAT00000020921; ENSBTAP00000020921; ENSBTAG00000015757.
DR GeneID; 616243; -.
DR KEGG; bta:616243; -.
DR CTD; 9796; -.
DR VEuPathDB; HostDB:ENSBTAG00000015757; -.
DR VGNC; VGNC:32850; PHYHIP.
DR eggNOG; ENOG502QQIT; Eukaryota.
DR GeneTree; ENSGT00390000014563; -.
DR HOGENOM; CLU_054218_1_0_1; -.
DR InParanoid; Q0VD34; -.
DR OMA; FQHVRMH; -.
DR OrthoDB; 659430at2759; -.
DR TreeFam; TF314485; -.
DR Proteomes; UP000009136; Chromosome 8.
DR Bgee; ENSBTAG00000015757; Expressed in cerebellum and 40 other tissues.
DR GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR GO; GO:1990782; F:protein tyrosine kinase binding; IEA:Ensembl.
DR GO; GO:0008104; P:protein localization; ISS:UniProtKB.
DR CDD; cd00063; FN3; 1.
DR Gene3D; 2.60.40.10; -; 1.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR042868; PHYHIP/PHYHIPL.
DR InterPro; IPR045545; PHYIP/PHIPL_C.
DR PANTHER; PTHR15698; PTHR15698; 1.
DR Pfam; PF19281; PHYHIP_C; 1.
DR SUPFAM; SSF49265; SSF49265; 1.
DR PROSITE; PS50853; FN3; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Reference proteome.
FT CHAIN 1..330
FT /note="Phytanoyl-CoA hydroxylase-interacting protein"
FT /id="PRO_0000285812"
FT DOMAIN 6..115
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00316"
FT CARBOHYD 14
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 325
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 330 AA; 37561 MW; 7B4A863B38BA6980 CRC64;
MELLSTPHSI EVSNITCDSF RISWTMENSD LERVTHYFID LNKKENKNSN KFKHRDVPTK
LVAKAVPLPM TVRGHWFLSP RTEYSVAVQT AVKQSDGEYL VSGWSETVEF CTGDYAKEHL
AQLQEKAEQI AGRMLRFSVF YRNHHKEYFQ HARTHCGNML QPYLKDNSGS HGSPTSGMLH
GVFFSCNTEF NTGQPPQDSP YGRWRFQIPA QRLFNPSTNL YFADFYCMYT AYHYAILVLA
PKGSLGDRFC RDRLPLLDIA CNKFLTCSVE DGELVFRHAQ DLILEIIYTE PVDLSLGTLG
EISGHQLMSL STADAKKDPS CKTCNISVGR