ID   PHYIP_PONAB             Reviewed;         330 AA.
AC   Q5R4I8; Q5R720;
DT   01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=Phytanoyl-CoA hydroxylase-interacting protein;
DE   AltName: Full=Phytanoyl-CoA hydroxylase-associated protein 1;
DE            Short=PAHX-AP1;
DE            Short=PAHXAP1;
GN   Name=PHYHIP;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain cortex;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Its interaction with PHYH suggests a role in the development
CC       of the central system. {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with PHYH and ADGRB1. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the PHYHIP family. {ECO:0000305}.
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DR   EMBL; CR860303; CAH92440.1; -; mRNA.
DR   EMBL; CR861260; CAH93328.1; -; mRNA.
DR   RefSeq; NP_001126439.1; NM_001132967.1.
DR   AlphaFoldDB; Q5R4I8; -.
DR   SMR; Q5R4I8; -.
DR   STRING; 9601.ENSPPYP00000020639; -.
DR   Ensembl; ENSPPYT00000061616; ENSPPYP00000027116; ENSPPYG00000037185.
DR   GeneID; 100173423; -.
DR   KEGG; pon:100173423; -.
DR   CTD; 9796; -.
DR   eggNOG; ENOG502QQIT; Eukaryota.
DR   GeneTree; ENSGT00390000014563; -.
DR   InParanoid; Q5R4I8; -.
DR   OrthoDB; 659430at2759; -.
DR   Proteomes; UP000001595; Chromosome 8.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:1990782; F:protein tyrosine kinase binding; IEA:Ensembl.
DR   GO; GO:0008104; P:protein localization; ISS:UniProtKB.
DR   CDD; cd00063; FN3; 1.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR003961; FN3_dom.
DR   InterPro; IPR036116; FN3_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR042868; PHYHIP/PHYHIPL.
DR   InterPro; IPR045545; PHYIP/PHIPL_C.
DR   PANTHER; PTHR15698; PTHR15698; 1.
DR   Pfam; PF19281; PHYHIP_C; 1.
DR   SUPFAM; SSF49265; SSF49265; 1.
DR   PROSITE; PS50853; FN3; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Reference proteome.
FT   CHAIN           1..330
FT                   /note="Phytanoyl-CoA hydroxylase-interacting protein"
FT                   /id="PRO_0000285813"
FT   DOMAIN          6..115
FT                   /note="Fibronectin type-III"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00316"
FT   CARBOHYD        14
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        325
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        67
FT                   /note="P -> A (in Ref. 1; CAH92440)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   330 AA;  37573 MW;  777199E6BB071D1C CRC64;
     MELLSTPHSI EINNITCDSF RISWAMEDSD LERVTHYFID LNKKENKNSN KFKHRDVPTK
     LVAKAVPLPM TVRGHWFLSP RTEYSVAVQT AVKQSDGEYL VSGWSETVEF CTGDYAKEHL
     AQLQEKAEQI AGRMLRFSVF YRNHHKEYFQ HARTHCGNML QPYLKDNSGS HGSPTSGMLH
     GVFFSCNTEF NTGQPPQDSP YGRWRFQIPA QRLFNPSTNL YFADFYCMYT AYHYAILVLA
     PKGSLGDRFC RDRLPLLDIA CNKFLTCSVE DGELVFRHAQ DLILEIIYTE PVDLSLGTLG
     EISGHQLMSL STADAKKDPS CKTCNISVGR