ID   PHYK_MAIZE              Reviewed;         303 AA.
AC   Q2N2K4; Q2N2K5;
DT   07-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT   07-FEB-2006, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Probable phytol kinase, chloroplastic;
DE            EC=2.7.1.182;
DE   Flags: Precursor;
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=16361393; DOI=10.1105/tpc.105.037077;
RA   Valentin H.E., Lincoln K., Moshiri F., Jensen P.K., Qi Q., Venkatesh T.V.,
RA   Karunanandaa B., Baszis S.R., Norris S.R., Savidge B., Gruys K.J.,
RA   Last R.L.;
RT   "The Arabidopsis vitamin E pathway gene5-1 mutant reveals a critical role
RT   for phytol kinase in seed tocopherol biosynthesis.";
RL   Plant Cell 18:212-224(2006).
CC   -!- FUNCTION: Involved in the activation and reutilization of phytol from
CC       chlorophyll degradation in plant metabolism, including tocopherol
CC       biosynthesis. Catalyzes the conversion of phytol to phytol
CC       monophosphate (PMP) (By similarity). {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=CTP + phytol = CDP + H(+) + phytyl phosphate;
CC         Xref=Rhea:RHEA:38055, ChEBI:CHEBI:15378, ChEBI:CHEBI:17327,
CC         ChEBI:CHEBI:37563, ChEBI:CHEBI:58069, ChEBI:CHEBI:75483;
CC         EC=2.7.1.182;
CC   -!- PATHWAY: Cofactor biosynthesis; tocopherol biosynthesis.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast membrane {ECO:0000305};
CC       Multi-pass membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the polyprenol kinase family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABA42672.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; DQ163023; ABA42672.1; ALT_INIT; mRNA.
DR   EMBL; DQ163024; ABA42673.1; -; mRNA.
DR   RefSeq; NP_001105847.1; NM_001112377.1.
DR   AlphaFoldDB; Q2N2K4; -.
DR   STRING; 4577.GRMZM2G104538_P01; -.
DR   PaxDb; Q2N2K4; -.
DR   EnsemblPlants; Zm00001eb066790_T002; Zm00001eb066790_P002; Zm00001eb066790.
DR   GeneID; 732748; -.
DR   Gramene; Zm00001eb066790_T002; Zm00001eb066790_P002; Zm00001eb066790.
DR   KEGG; zma:732748; -.
DR   eggNOG; KOG4453; Eukaryota.
DR   HOGENOM; CLU_058561_2_1_1; -.
DR   OMA; SWPIFST; -.
DR   OrthoDB; 1323987at2759; -.
DR   UniPathway; UPA00160; -.
DR   Proteomes; UP000007305; Chromosome 2.
DR   ExpressionAtlas; Q2N2K4; baseline and differential.
DR   Genevisible; Q2N2K4; ZM.
DR   GO; GO:0031969; C:chloroplast membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016301; F:kinase activity; IBA:GO_Central.
DR   GO; GO:0010276; F:phytol kinase activity; IBA:GO_Central.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   GO; GO:0010189; P:vitamin E biosynthetic process; IBA:GO_Central.
DR   InterPro; IPR039606; Phytol/farnesol_kinase.
DR   PANTHER; PTHR32523; PTHR32523; 1.
PE   2: Evidence at transcript level;
KW   Chloroplast; Kinase; Membrane; Plastid; Reference proteome; Transferase;
KW   Transit peptide; Transmembrane; Transmembrane helix.
FT   TRANSIT         1..49
FT                   /note="Chloroplast"
FT                   /evidence="ECO:0000255"
FT   CHAIN           50..303
FT                   /note="Probable phytol kinase, chloroplastic"
FT                   /id="PRO_0000226596"
FT   TRANSMEM        98..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        122..144
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        168..188
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        227..247
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        254..274
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        276..296
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        114
FT                   /note="F -> V (in Ref. 1; ABA42672)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   303 AA;  32582 MW;  CBA34DCF6D3A1A82 CRC64;
     MAAAAAWTGA ASPNSLLLSR SPPHAAALAP SPGSSMRRRL LLGVGTPAVA ALAAAAPPAV
     LQDGAVTVLI TAGAYSLVRV FDELTERRLI EKSLSRKVVH VLSGVLFMSS WPLFSNSTEA
     RYFAAVVPFL NSMRLLIYGL RLYTDEALVK SVTREGKPEE LLRGPLYYVL VLLFSVLVFW
     RESPIGIVSL SMMSGGDGFA DIVGRRYGSA KLPFNRKKSW AGSISMFISG FLLSAMMMLY
     FSSLGYIDVI WEEALGKLAL VALAATVVEC VPVTEVVDDN ISVPLATMLV AFLLFSSNRT
     IVN