ID   PHYK_WHEAT              Reviewed;         300 AA.
AC   Q2N2K3;
DT   07-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT   07-FEB-2006, sequence version 1.
DT   03-AUG-2022, entry version 53.
DE   RecName: Full=Probable phytol kinase, chloroplastic;
DE            EC=2.7.1.182;
DE   Flags: Precursor;
OS   Triticum aestivum (Wheat).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX   NCBI_TaxID=4565;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=16361393; DOI=10.1105/tpc.105.037077;
RA   Valentin H.E., Lincoln K., Moshiri F., Jensen P.K., Qi Q., Venkatesh T.V.,
RA   Karunanandaa B., Baszis S.R., Norris S.R., Savidge B., Gruys K.J.,
RA   Last R.L.;
RT   "The Arabidopsis vitamin E pathway gene5-1 mutant reveals a critical role
RT   for phytol kinase in seed tocopherol biosynthesis.";
RL   Plant Cell 18:212-224(2006).
CC   -!- FUNCTION: Involved in the activation and reutilization of phytol from
CC       chlorophyll degradation in plant metabolism, including tocopherol
CC       biosynthesis. Catalyzes the conversion of phytol to phytol
CC       monophosphate (PMP) (By similarity). {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=CTP + phytol = CDP + H(+) + phytyl phosphate;
CC         Xref=Rhea:RHEA:38055, ChEBI:CHEBI:15378, ChEBI:CHEBI:17327,
CC         ChEBI:CHEBI:37563, ChEBI:CHEBI:58069, ChEBI:CHEBI:75483;
CC         EC=2.7.1.182;
CC   -!- PATHWAY: Cofactor biosynthesis; tocopherol biosynthesis.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast membrane {ECO:0000305};
CC       Multi-pass membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the polyprenol kinase family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DQ163025; ABA42674.1; -; mRNA.
DR   AlphaFoldDB; Q2N2K3; -.
DR   STRING; 4565.Traes_2AL_C0BC1CE02.2; -.
DR   PRIDE; Q2N2K3; -.
DR   EnsemblPlants; TraesCAD_scaffold_115222_01G000200.1; TraesCAD_scaffold_115222_01G000200.1; TraesCAD_scaffold_115222_01G000200.
DR   EnsemblPlants; TraesCLE_scaffold_005444_01G000100.1; TraesCLE_scaffold_005444_01G000100.1; TraesCLE_scaffold_005444_01G000100.
DR   EnsemblPlants; TraesPAR_scaffold_128995_01G000100.1; TraesPAR_scaffold_128995_01G000100.1; TraesPAR_scaffold_128995_01G000100.
DR   EnsemblPlants; TraesROB_scaffold_137322_01G000100.1; TraesROB_scaffold_137322_01G000100.1; TraesROB_scaffold_137322_01G000100.
DR   EnsemblPlants; TraesWEE_scaffold_123429_01G000200.1; TraesWEE_scaffold_123429_01G000200.1; TraesWEE_scaffold_123429_01G000200.
DR   Gramene; TraesCAD_scaffold_115222_01G000200.1; TraesCAD_scaffold_115222_01G000200.1; TraesCAD_scaffold_115222_01G000200.
DR   Gramene; TraesCLE_scaffold_005444_01G000100.1; TraesCLE_scaffold_005444_01G000100.1; TraesCLE_scaffold_005444_01G000100.
DR   Gramene; TraesPAR_scaffold_128995_01G000100.1; TraesPAR_scaffold_128995_01G000100.1; TraesPAR_scaffold_128995_01G000100.
DR   Gramene; TraesROB_scaffold_137322_01G000100.1; TraesROB_scaffold_137322_01G000100.1; TraesROB_scaffold_137322_01G000100.
DR   Gramene; TraesWEE_scaffold_123429_01G000200.1; TraesWEE_scaffold_123429_01G000200.1; TraesWEE_scaffold_123429_01G000200.
DR   eggNOG; KOG4453; Eukaryota.
DR   UniPathway; UPA00160; -.
DR   Proteomes; UP000019116; Unplaced.
DR   ExpressionAtlas; Q2N2K3; baseline and differential.
DR   GO; GO:0031969; C:chloroplast membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016301; F:kinase activity; IBA:GO_Central.
DR   GO; GO:0010276; F:phytol kinase activity; IBA:GO_Central.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   GO; GO:0010189; P:vitamin E biosynthetic process; IBA:GO_Central.
DR   InterPro; IPR039606; Phytol/farnesol_kinase.
DR   PANTHER; PTHR32523; PTHR32523; 1.
PE   2: Evidence at transcript level;
KW   Chloroplast; Kinase; Membrane; Plastid; Reference proteome; Transferase;
KW   Transit peptide; Transmembrane; Transmembrane helix.
FT   TRANSIT         1..36
FT                   /note="Chloroplast"
FT                   /evidence="ECO:0000255"
FT   CHAIN           37..300
FT                   /note="Probable phytol kinase, chloroplastic"
FT                   /id="PRO_0000226597"
FT   TRANSMEM        60..78
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        98..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        122..142
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        168..188
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        227..247
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        254..274
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        276..296
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   300 AA;  32110 MW;  541F1E4F23C889E8 CRC64;
     MAAARPALPS SPTSLLLARS TSAPDLAARR PRRWLVAAAG VPAVAGALAA SASTPAASML
     LRDGGATLLV TAGAYSLVRA FDALTERRLV QQSLSRKVVH VLSGVFFMAS WPLFSNSTSA
     RFFAAVVPFL NCVRLLTYGL GFYSDEALVK SVTREGKREE LLRGPLYYVI VLLIIVLVFW
     RDSPIGIVSL SMMSGGDGFA DIVGRRFGSL KLPFNKKKSW VGSAAMFISG FLLSALMLSY
     FSWLGYIHVS WDQALGKLVL VALAATVVEC IPVTDVVDDN ISVPLATMLV AFLLFGNTAN