PIA2_PLEOS
ID PIA2_PLEOS Reviewed; 76 AA.
AC Q7M4T5;
DT 10-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT 15-DEC-2003, sequence version 1.
DT 25-MAY-2022, entry version 48.
DE RecName: Full=Serine proteinase inhibitor IA-2;
DE AltName: Full=Proteinase A inhibitor 2;
OS Pleurotus ostreatus (Oyster mushroom) (White-rot fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Pleurotaceae; Pleurotus.
OX NCBI_TaxID=5322;
RN [1]
RP PROTEIN SEQUENCE, AND ACETYLATION AT SER-1.
RX PubMed=7840656; DOI=10.1006/abbi.1995.1066;
RA Dohmae N., Takio K., Tsumuraya Y., Hashimoto Y.;
RT "The complete amino acid sequences of two serine proteinase inhibitors from
RT the fruiting bodies of a basidiomycete, Pleurotus ostreatus.";
RL Arch. Biochem. Biophys. 316:498-506(1995).
CC -!- FUNCTION: Specifically inhibits an intracellular serine proteinase
CC (proteinase A).
CC -!- SIMILARITY: Belongs to the protease inhibitor I9 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR PIR; S69163; S69163.
DR AlphaFoldDB; Q7M4T5; -.
DR SMR; Q7M4T5; -.
DR MEROPS; I09.002; -.
DR iPTMnet; Q7M4T5; -.
DR VEuPathDB; FungiDB:PLEOSDRAFT_1089399; -.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.80; -; 1.
DR InterPro; IPR037045; S8pro/Inhibitor_I9_sf.
PE 1: Evidence at protein level;
KW Acetylation; Direct protein sequencing; Protease inhibitor;
KW Serine protease inhibitor.
FT CHAIN 1..76
FT /note="Serine proteinase inhibitor IA-2"
FT /id="PRO_0000212792"
FT MOD_RES 1
FT /note="N-acetylserine"
FT /evidence="ECO:0000269|PubMed:7840656"
SQ SEQUENCE 76 AA; 8195 MW; 796748998BD34541 CRC64;
SAGKFIVIFK NGVSDDKIRE TKDEVIAEGG TITNEYNMPG MKGFAGELTP QSLTKFQGLQ
GDLIDSIEED GIVTTQ