PICBP_ARATH
ID PICBP_ARATH Reviewed; 1488 AA.
AC A0A1P8BH59; Q8H6X1; Q9LZA8;
DT 25-OCT-2017, integrated into UniProtKB/Swiss-Prot.
DT 12-APR-2017, sequence version 1.
DT 25-MAY-2022, entry version 29.
DE RecName: Full=Calmodulin binding protein PICBP {ECO:0000305};
DE AltName: Full=Pathogen-induced CaM-binding protein {ECO:0000303|PubMed:12825696};
GN Name=PICBP {ECO:0000303|PubMed:12825696};
GN OrderedLocusNames=At5g04020 {ECO:0000312|Araport:AT5G04020};
GN ORFNames=F8F6_230 {ECO:0000312|EMBL:CAB85522.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 332-1488, FUNCTION, AND INDUCTION.
RX PubMed=12825696; DOI=10.1023/a:1023993713849;
RA Reddy V.S., Ali G.S., Reddy A.S.;
RT "Characterization of a pathogen-induced calmodulin-binding protein: mapping
RT of four Ca2+-dependent calmodulin-binding domains.";
RL Plant Mol. Biol. 52:143-159(2003).
CC -!- FUNCTION: Binds calmodulin in a calcium-dependent manner in vitro. May
CC play a role in general plant defense including R gene-mediated
CC responses. {ECO:0000269|PubMed:12825696}.
CC -!- INDUCTION: Induced by infection with the bacterial pathogen Pseudomonas
CC syringae pv tomato strain DC3000 carrying the avirulent factor avrRpm1.
CC {ECO:0000269|PubMed:12825696}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAB85522.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AL162873; CAB85522.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED90685.2; -; Genomic_DNA.
DR EMBL; CP002688; ANM70933.1; -; Genomic_DNA.
DR EMBL; AF438330; AAN63625.1; -; mRNA.
DR PIR; T48429; T48429.
DR RefSeq; NP_001318476.1; NM_001342742.1.
DR RefSeq; NP_001332504.1; NM_001342743.1.
DR AlphaFoldDB; A0A1P8BH59; -.
DR SMR; A0A1P8BH59; -.
DR iPTMnet; A0A1P8BH59; -.
DR ProteomicsDB; 226175; -.
DR EnsemblPlants; AT5G04020.1; AT5G04020.1; AT5G04020.
DR EnsemblPlants; AT5G04020.2; AT5G04020.2; AT5G04020.
DR GeneID; 830281; -.
DR Gramene; AT5G04020.1; AT5G04020.1; AT5G04020.
DR Gramene; AT5G04020.2; AT5G04020.2; AT5G04020.
DR KEGG; ath:AT5G04020; -.
DR Araport; AT5G04020; -.
DR TAIR; locus:2150615; AT5G04020.
DR eggNOG; ENOG502QV73; Eukaryota.
DR OMA; WRILCKQ; -.
DR OrthoDB; 78330at2759; -.
DR PRO; PR:A0A1P8BH59; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; A0A1P8BH59; baseline and differential.
DR GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR InterPro; IPR012417; CaM-bd_dom_pln.
DR InterPro; IPR044681; PICBP-like.
DR PANTHER; PTHR33923; PTHR33923; 5.
DR Pfam; PF07839; CaM_binding; 4.
DR SMART; SM01054; CaM_binding; 4.
PE 2: Evidence at transcript level;
KW Calmodulin-binding; Plant defense; Reference proteome.
FT CHAIN 1..1488
FT /note="Calmodulin binding protein PICBP"
FT /id="PRO_0000442224"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 63..112
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 280..329
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 378..414
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 493..592
FT /note="Calmodulin-binding"
FT /evidence="ECO:0000255"
FT REGION 816..844
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 831..938
FT /note="Calmodulin-binding"
FT /evidence="ECO:0000255"
FT REGION 941..971
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1135..1229
FT /note="Calmodulin-binding"
FT /evidence="ECO:0000255"
FT REGION 1232..1252
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1316..1341
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1379..1483
FT /note="Calmodulin-binding"
FT /evidence="ECO:0000255"
FT COMPBIAS 79..99
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 295..312
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 315..329
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 396..414
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 828..844
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1488 AA; 168618 MW; 93262128208BEE38 CRC64;
MSNPMFPEKW EESSTSKSSR RVHKRRERKM WKKPIKLSRF PSFGFSGSDF TLDQIPAIFS
GYTAESEDSS SSEMSDDSRT YSKSSDENEE LDQERPRSVK RRAKSKSISR ISSMKVLRRQ
STRTLYGAGQ RLKKMRSMKR LTSNSRQILR KKNLDRGDFG LLQPHYLRPT SSSASKNVEN
NQKNLGAARL KRIASLRYNG LLKATCSSAM KGSSSKRSND VCTYRYCSLH GRRHSHAADN
NAGVPSLKRF VSMRRKFMNR QKSVNRRLVL LKRTLSRKRG PLGGRVVTDQ ESKEVDDNVD
GDSDEEVFEE EVSSSVDGGN DNESIGRSSE TVMVDVDDNV DRGMDAMETV ASKVQESKTE
TVGATLWRAI CEQTVTGHDH DDGKVDGTTS DGTVGDNEEV CREGSSGELR EEDGKKTEYV
WNETVTLVKQ AFDEILAEIT DDDSSDDISM TKDEALEVGL GEEDVGADSS DSSCSDMQPV
IERDTHLSVI ASTFHMRDEF GHQRGPKKWS YLKRVILLKR FLKSLDRKER RKLSDGKESE
TIMRLRRELV GERKNAEEWM LDHALRQVIS TLAPSQKKKV KHLVKAFESL IPMDGGSRGH
DDLVSPAREE NETVNSQTQT ILRDNKDATD ILEVSPAKDL EETNLTCEAS SFLSIDMKSD
EENETVNSPT IWRDNEDTTD LLEVVPAKDL EETNLTSESS SSLCIGMKSD EALESTADAS
LCNHLAVEEE VDGLALGSFI EEEEKKGESE KQNLSTWRNL IQKHMVMRDN SEGNRNETEQ
EHKWSYGTDQ MTGIDDANAA AVKSIQLAFE TILSEIPDSS SDEESVSESS NSLKEEKEHQ
GETKRSWNSL RKVILLKRFV KSLEKVQVPN PRKMRNLPVE SAFEAENVFL RHRSIMEGTR
TEGEEMMLDY ALRQAISRLA PIQRKKVDLL VQAFDIVLDG HDTPKQTKNS DTPRNNDETK
EGKPRVEEGC EVNKDEQKIK NVFARFQVHQ KDLKGEEEVH NTPKESRNLP PIRNFKQRIV
VEKGKDSRMW KLIYKHMVTE KEGIDSANAE SVASVESEYD DEAGGLQIDA RRSGTVTLVR
EALEKILSEI PDNSSDDQSM DSDITTEQEL FERNSQVSEE KSEVSSATFK PKFTEKRVKG
WNNVKKVILL KRFVSDLGSL TRLSPKTPRV LPWEPDPETE KIRLRHQEIG GKRNSEEWML
DYALRQAIST LAPSQKRKVS LLAQAFDTIS LQDMGSGSTP GSAASSRNIS RQSSISSMAA
HYENEANAEI IRGKLRNLQE DLKESAKLDG VSKDLEEKQQ CSSLWRILCK QMEDNEKNQT
LPEETRKEEE EEELKEDTSV DGEKMELYQT EAVELLGEVI DGISLEESQD QNLNNEETRQ
KSETLQVSKV RIDRWSNLKR AILLRRFVKA LENVRKFNPR EPRFLPPNPE VEAEKVNLRH
QETQNKKNGD EWMVDNALQG VVSKLTPARK LKVQLLVQAF ESLSATGN
