ID   PICO_DROAN              Reviewed;         483 AA.
AC   O61369;
DT   28-MAR-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Putative inorganic phosphate cotransporter;
GN   Name=Picot;
OS   Drosophila ananassae (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7217;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Tai 13-1610;
RA   Da Lage J.-L., Alland C.;
RL   Submitted (SEP-1997) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be an inorganic phosphate cotransporter.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. Sodium/anion
CC       cotransporter family. {ECO:0000305}.
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DR   EMBL; AF024691; AAC39088.1; -; Genomic_DNA.
DR   AlphaFoldDB; O61369; -.
DR   SMR; O61369; -.
DR   STRING; 7217.FBpp0116648; -.
DR   eggNOG; KOG2532; Eukaryota.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015114; F:phosphate ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1250.20; -; 2.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR004745; Pi_cotranspt.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   TIGRFAMs; TIGR00894; 2A0114euk; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
KW   Ion transport; Membrane; Sodium; Sodium transport; Symport; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..483
FT                   /note="Putative inorganic phosphate cotransporter"
FT                   /id="PRO_0000220945"
FT   TRANSMEM        64..84
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        90..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        187..207
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        292..312
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        349..369
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        383..403
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        420..440
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          447..483
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        456..483
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   483 AA;  52885 MW;  6832750611B775F0 CRC64;
     MLFLGMANAY VMRTNMSVAI VAMVNHTAIK SGEEEYDDEC GDRDIPIDDS QDGEFPWNAA
     LQGYILSSFF YGYVITQIPF GILAKKYGSL RFLGYGMLIN SVFAFLVPVA AREGGVWGLC
     AVRFIQGLGE GPIVPCTHAM LAKWIPPNER SRMGAAVYAG AQFGTIISMP LSGLLAEYGF
     DGGWPSIFYV FGIVGTVWSI AFLIFVYEDP STHPKIDERE KKYINESLWG TDVIKSPPIP
     FKSIVKSLPF YAILFAHMGH NYGYETLMTE LPTYMKQVLR FSLKSNGLLS SLPYLAMWLL
     SMFISVIADW MISSKRFSLT ATRKIINSIG QYGPGLALIA ASYTGCDRAL TLAILTIGVG
     LNGGIYSGFK INHLDLTPRF AGFLMSITNC SANLAGLLAP IAAGNLISDP SKPVMGQWQI
     VFFIAAFVYI ICGTFYNIFG SGERQFWDNP SEDEQKPALE SSSTTNPPRL SNGSSAPRAI
     SSS