ID   PIF3_NPVAC              Reviewed;         204 AA.
AC   P41668;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   29-SEP-2021, entry version 44.
DE   RecName: Full=Per os infectivity factor 3;
DE            Short=PIF3;
GN   Name=AC115; ORFNames=ORF115;
OS   Autographa californica nuclear polyhedrosis virus (AcMNPV).
OC   Viruses; Naldaviricetes; Lefavirales; Baculoviridae; Alphabaculovirus.
OX   NCBI_TaxID=46015;
OH   NCBI_TaxID=7088; Lepidoptera (butterflies and moths).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C6;
RX   PubMed=8030224; DOI=10.1006/viro.1994.1380;
RA   Ayres M.D., Howard S.C., Kuzio J., Lopez-Ferber M., Possee R.D.;
RT   "The complete DNA sequence of Autographa californica nuclear polyhedrosis
RT   virus.";
RL   Virology 202:586-605(1994).
RN   [2]
RP   FUNCTION.
RX   PubMed=16306597; DOI=10.1128/jvi.79.24.15258-15264.2005;
RA   Ohkawa T., Washburn J.O., Sitapara R., Sid E., Volkman L.E.;
RT   "Specific binding of Autographa californica M nucleopolyhedrovirus
RT   occlusion-derived virus to midgut cells of Heliothis virescens larvae is
RT   mediated by products of pif genes Ac119 and Ac022 but not by Ac115.";
RL   J. Virol. 79:15258-15264(2005).
RN   [3]
RP   INTERACTION WITH PIF1; PIF2 AND PIF0.
RX   PubMed=20610731; DOI=10.1128/jvi.00812-10;
RA   Peng K., van Oers M.M., Hu Z., van Lent J.W., Vlak J.M.;
RT   "Baculovirus per os infectivity factors form a complex on the surface of
RT   occlusion-derived virus.";
RL   J. Virol. 84:9497-9504(2010).
CC   -!- FUNCTION: Per os factor that plays a role in the initiation of host
CC       midgut infection. Unlike PIF1 and PIF2, PIF3 is not involved in
CC       specific binding of occluded virions (ODV) to the host midgut target
CC       cells. {ECO:0000269|PubMed:20610731}.
CC   -!- SUBUNIT: Forms the PIF complex together with PIF1 and PIF2. The complex
CC       interacts also with per os infectivity factor PIF0.
CC       {ECO:0000269|PubMed:20610731}.
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DR   EMBL; L22858; AAA66745.1; -; Genomic_DNA.
DR   PIR; D72864; D72864.
DR   RefSeq; NP_054145.1; NC_001623.1.
DR   GeneID; 1403948; -.
DR   KEGG; vg:1403948; -.
DR   Proteomes; UP000008292; Genome.
DR   InterPro; IPR007703; PIF3.
DR   Pfam; PF05006; PIF3; 1.
PE   1: Evidence at protein level;
KW   Reference proteome.
FT   CHAIN           1..204
FT                   /note="Per os infectivity factor 3"
FT                   /id="PRO_0000133053"
SQ   SEQUENCE   204 AA;  23019 MW;  2EA2A52874C9A4AF CRC64;
     MLNFWQILIL LVIILIVYMY TFKFVQKFIL QDAYMHINEL EAPPLNFTFQ RNRGVDCSLN
     RLPCVTDQQC RDNCVISSAA NELTCQDGFC NASDALVNAQ APDLIECDPA LGLVHVFSAG
     GDFVVSQTCV STYRDLVDDT GTPRPYLCND GRLNMNLNTV QFSPDACDCS SGYEKMLFRQ
     TALARTIPVC IPNRMANLYR RVYN