ID   PIF6_NPVAC              Reviewed;         192 AA.
AC   P41468;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   29-SEP-2021, entry version 44.
DE   RecName: Full=Per os infectivity factor 6;
DE            Short=PIF6;
GN   Name=AC68; ORFNames=ORF68;
OS   Autographa californica nuclear polyhedrosis virus (AcMNPV).
OC   Viruses; Naldaviricetes; Lefavirales; Baculoviridae; Alphabaculovirus.
OX   NCBI_TaxID=46015;
OH   NCBI_TaxID=7088; Lepidoptera (butterflies and moths).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C6;
RX   PubMed=8030224; DOI=10.1006/viro.1994.1380;
RA   Ayres M.D., Howard S.C., Kuzio J., Lopez-Ferber M., Possee R.D.;
RT   "The complete DNA sequence of Autographa californica nuclear polyhedrosis
RT   virus.";
RL   Virology 202:586-605(1994).
RN   [2]
RP   FUNCTION, AND SUBCELLULAR LOCATION.
RX   PubMed=22278232; DOI=10.1128/jvi.06849-11;
RA   Nie Y., Fang M., Erlandson M.A., Theilmann D.A.;
RT   "Analysis of the autographa californica multiple nucleopolyhedrovirus
RT   overlapping gene pair lef3 and ac68 reveals that AC68 is a per os
RT   infectivity factor and that LEF3 is critical, but not essential, for virus
RT   replication.";
RL   J. Virol. 86:3985-3994(2012).
CC   -!- FUNCTION: Per os infectivity factor. {ECO:0000269|PubMed:22278232}.
CC   -!- SUBCELLULAR LOCATION: Host membrane {ECO:0000255}; Single-pass membrane
CC       protein {ECO:0000255}. Virion {ECO:0000269|PubMed:22278232}. Host
CC       cytoplasm {ECO:0000269|PubMed:22278232}. Host nucleus
CC       {ECO:0000269|PubMed:22278232}. Note=Present in both the budded virus
CC       (BV) and the occluded-derived virus (ODV).
CC       {ECO:0000269|PubMed:22278232}.
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DR   EMBL; L22858; AAA66698.1; -; Genomic_DNA.
DR   PIR; E72858; E72858.
DR   RefSeq; NP_054098.1; NC_001623.1.
DR   GeneID; 1403901; -.
DR   KEGG; vg:1403901; -.
DR   Proteomes; UP000008292; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR008005; PIF6.
DR   Pfam; PF05341; PIF6; 1.
PE   3: Inferred from homology;
KW   Host cytoplasm; Host membrane; Host nucleus; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Virion.
FT   CHAIN           1..192
FT                   /note="Per os infectivity factor 6"
FT                   /id="PRO_0000133006"
FT   TRANSMEM        154..174
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   192 AA;  22334 MW;  FFD7ADC60C7C6220 CRC64;
     MVFIIDTQRH FAHQFTTNPF VIFSNLLGAT GHSHAFYKRL TATFSRQRSF GRHIAVVDMW
     ESIRWQILNG DEIEVSPEHR SLAWRELIIN VASNTPLDNT FRTMFQKADF ENFDYNTPIV
     YNLKTKTLTM YNERIRAALN RPVRFNDQTV NVNIAYVFLF FICIVLLSVL AVFFDTNIAT
     DTKSKNVAAK IK