位置:首页 > 蛋白库 > PIG10_CLAP2
PIG10_CLAP2
ID   PIG10_CLAP2             Reviewed;         467 AA.
AC   M1WG94;
DT   25-APR-2018, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2013, sequence version 1.
DT   03-AUG-2022, entry version 23.
DE   RecName: Full=Ergochrome gene cluster transcriptional coactivator CPUR_05432 {ECO:0000303|PubMed:28955461};
DE   AltName: Full=Ergochrome gene cluster protein CPUR_05432 {ECO:0000303|PubMed:28955461};
GN   ORFNames=CPUR_05432;
OS   Claviceps purpurea (strain 20.1) (Ergot fungus) (Sphacelia segetum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Clavicipitaceae; Claviceps.
OX   NCBI_TaxID=1111077;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=20.1;
RX   PubMed=23468653; DOI=10.1371/journal.pgen.1003323;
RA   Schardl C.L., Young C.A., Hesse U., Amyotte S.G., Andreeva K., Calie P.J.,
RA   Fleetwood D.J., Haws D.C., Moore N., Oeser B., Panaccione D.G.,
RA   Schweri K.K., Voisey C.R., Farman M.L., Jaromczyk J.W., Roe B.A.,
RA   O'Sullivan D.M., Scott B., Tudzynski P., An Z., Arnaoudova E.G.,
RA   Bullock C.T., Charlton N.D., Chen L., Cox M., Dinkins R.D., Florea S.,
RA   Glenn A.E., Gordon A., Gueldener U., Harris D.R., Hollin W., Jaromczyk J.,
RA   Johnson R.D., Khan A.K., Leistner E., Leuchtmann A., Li C., Liu J., Liu J.,
RA   Liu M., Mace W., Machado C., Nagabhyru P., Pan J., Schmid J., Sugawara K.,
RA   Steiner U., Takach J.E., Tanaka E., Webb J.S., Wilson E.V., Wiseman J.L.,
RA   Yoshida R., Zeng Z.;
RT   "Plant-symbiotic fungi as chemical engineers: Multi-genome analysis of the
RT   Clavicipitaceae reveals dynamics of alkaloid loci.";
RL   PLoS Genet. 9:E1003323-E1003323(2013).
RN   [2]
RP   FUNCTION, AND INDUCTION.
RX   PubMed=28955461; DOI=10.1186/s40694-016-0020-z;
RA   Neubauer L., Dopstadt J., Humpf H.U., Tudzynski P.;
RT   "Identification and characterization of the ergochrome gene cluster in the
RT   plant pathogenic fungus Claviceps purpurea.";
RL   Fungal Biol. Biotechnol. 3:2-2(2016).
CC   -!- FUNCTION: Transcriptional coactivator; part of the gene cluster
CC       responsible for the typical purple-black color of the ergot sclerotia
CC       (PubMed:28955461). The ergochrome gene cluster produces several ergot
CC       pigments including the yellow ergochrome secalonic acid and its
CC       derivatives, as well as the red anthraquinones endocrocin and
CC       clavorubin (PubMed:28955461). With CPUR_05433, coregulates the
CC       production of geodin (PubMed:28955461). {ECO:0000305|PubMed:28955461}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- INDUCTION: Expression correlates with the formation of the sclerotia
CC       and thus the pigment production (PubMed:28955461).
CC       {ECO:0000269|PubMed:28955461}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CAGA01000032; CCE31579.1; -; Genomic_DNA.
DR   AlphaFoldDB; M1WG94; -.
DR   SMR; M1WG94; -.
DR   STRING; 1111077.M1WG94; -.
DR   EnsemblFungi; CCE31579; CCE31579; CPUR_05432.
DR   VEuPathDB; FungiDB:CPUR_05432; -.
DR   eggNOG; KOG3178; Eukaryota.
DR   HOGENOM; CLU_005533_11_0_1; -.
DR   OrthoDB; 817726at2759; -.
DR   Proteomes; UP000016801; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   SUPFAM; SSF46785; SSF46785; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding; Nucleus; Reference proteome.
FT   CHAIN           1..467
FT                   /note="Ergochrome gene cluster transcriptional coactivator
FT                   CPUR_05432"
FT                   /id="PRO_0000443982"
FT   DOMAIN          109..179
FT                   /note="HTH iclR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00393"
FT   DNA_BIND        139..158
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00393"
SQ   SEQUENCE   467 AA;  50328 MW;  3B01A50ED44E9A9D CRC64;
     MEKLAALKKL PSILRPLLTS KSSYHRVPSD RPTIMDAATS EQLHGLTNRL LTEVNALVSS
     YSSIDCQHPF LAAACESQND GSEARSNILS SLSEIEAIVR GPKEFLENIA IQCEMLGSIQ
     WLGEFQILAC IPLSQEVPIQ DVANLSNVPE QQLAQMIGLT ARCGFLIEPR RGYVAHTPLS
     ASFVTNPSHL DAAMFLAEQA APAALKSATA TQRFTESHTN NETAFSLATT TKVPFEAAQE
     QSPRLSRQWA AYLHHAGGLP EDHVLADAMA KLHWSNISKA GGQVVEVGAF LAAKPLARLF
     PQLRFLVQLP AGASSCESIL CDPSDPIKPG QISIANRVPG SPQSVTNAAV YVLHLPSSVP
     SQILTELQVH LPALRMSNGV MLIMSGRVLP GQDEPIRARH AAVAHARGLI MYQMSNEVEM
     DLSSLLQMLD TVRDSTGKLV LVHKLRSCSG MTVAVVVKYQ LMAGGAS
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024