ID   PILH_PSEAE              Reviewed;         121 AA.
AC   P43501;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 115.
DE   RecName: Full=Protein PilH;
GN   Name=pilH; OrderedLocusNames=PA0409;
OS   Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS   14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208964;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RX   PubMed=7908398; DOI=10.1111/j.1365-2958.1994.tb00296.x;
RA   Darzins A.;
RT   "Characterization of a Pseudomonas aeruginosa gene cluster involved in
RT   pilus biosynthesis and twitching motility: sequence similarity to the
RT   chemotaxis proteins of enterics and the gliding bacterium Myxococcus
RT   xanthus.";
RL   Mol. Microbiol. 11:137-153(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RX   PubMed=10984043; DOI=10.1038/35023079;
RA   Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA   Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA   Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA   Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA   Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA   Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT   "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT   pathogen.";
RL   Nature 406:959-964(2000).
CC   -!- FUNCTION: May be a part of a signal-transduction system that regulates
CC       twitching motility by controlling pilus function (extension and
CC       retraction).
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DR   EMBL; L22036; AAA25950.1; -; Genomic_DNA.
DR   EMBL; AE004091; AAG03798.1; -; Genomic_DNA.
DR   PIR; S40035; S40035.
DR   RefSeq; NP_249100.1; NC_002516.2.
DR   RefSeq; WP_003084587.1; NZ_QZGE01000016.1.
DR   AlphaFoldDB; P43501; -.
DR   SMR; P43501; -.
DR   STRING; 287.DR97_3377; -.
DR   PaxDb; P43501; -.
DR   PRIDE; P43501; -.
DR   EnsemblBacteria; AAG03798; AAG03798; PA0409.
DR   GeneID; 878198; -.
DR   KEGG; pae:PA0409; -.
DR   PATRIC; fig|208964.12.peg.430; -.
DR   PseudoCAP; PA0409; -.
DR   HOGENOM; CLU_000445_69_17_6; -.
DR   InParanoid; P43501; -.
DR   OMA; VMCTSVE; -.
DR   PhylomeDB; P43501; -.
DR   BioCyc; PAER208964:G1FZ6-413-MON; -.
DR   Proteomes; UP000002438; Chromosome.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   Pfam; PF00072; Response_reg; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF52172; SSF52172; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   3: Inferred from homology;
KW   Phosphoprotein; Reference proteome; Two-component regulatory system.
FT   CHAIN           1..121
FT                   /note="Protein PilH"
FT                   /id="PRO_0000081204"
FT   DOMAIN          3..119
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT   MOD_RES         52
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   121 AA;  13273 MW;  8B0B5F65B2DC37C8 CRC64;
     MARILIVDDS PTEMYKLTAM LEKHGHQVLK AENGGDGVAL ARQEKPDVVL MDIVMPGLNG
     FQATRQLTKD AETSAIPVII VTTKDQETDK VWGKRQGARD YLTKPVDEET LLKTINAVLA
     G