PIN1A_ORYSJ
ID PIN1A_ORYSJ Reviewed; 595 AA.
AC Q5SMQ9; O81215; Q0DXM9;
DT 10-JAN-2006, integrated into UniProtKB/Swiss-Prot.
DT 21-DEC-2004, sequence version 1.
DT 03-AUG-2022, entry version 101.
DE RecName: Full=Auxin efflux carrier component 1a {ECO:0000305};
DE Short=OsPIN1a {ECO:0000303|Ref.7};
DE AltName: Full=Auxin efflux carrier component 1 {ECO:0000305};
DE Short=OsPIN1 {ECO:0000303|PubMed:16085936};
DE AltName: Full=Ethylene-insensitive root 1 homolog {ECO:0000303|PubMed:9679062};
DE AltName: Full=OsPIN1b {ECO:0000303|PubMed:19825657};
GN Name=PIN1A {ECO:0000303|Ref.7};
GN Synonyms=PIN1 {ECO:0000303|PubMed:16085936},
GN REH1 {ECO:0000303|PubMed:9679062};
GN OrderedLocusNames=Os02g0743400 {ECO:0000312|EMBL:BAS80873.1},
GN LOC_Os02g50960 {ECO:0000305};
GN ORFNames=OJ1734_E02.14 {ECO:0000312|EMBL:BAD72501.1},
GN OsJ_08350 {ECO:0000312|EMBL:EEE57795.1},
GN P0585G03.37 {ECO:0000312|EMBL:BAD72497.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=9679062; DOI=10.1101/gad.12.14.2175;
RA Luschnig C., Gaxiola R.A., Grisafi P., Fink G.R.;
RT "EIR1, a root-specific protein involved in auxin transport, is required for
RT gravitropism in Arabidopsis thaliana.";
RL Genes Dev. 12:2175-2187(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [7]
RP IDENTIFICATION.
RX DOI=10.1016/j.plantsci.2010.02.018;
RA Miyashita Y., Takasugi T., Ito Y.;
RT "Identification and expression analysis of PIN genes in rice.";
RL Plant Sci. 178:424-428(2010).
RN [8]
RP FUNCTION, TISSUE SPECIFICITY, AND NOMENCLATURE.
RX PubMed=16085936; DOI=10.1093/pcp/pci183;
RA Xu M., Zhu L., Shou H., Wu P.;
RT "A PIN1 family gene, OsPIN1, involved in auxin-dependent adventitious root
RT emergence and tillering in rice.";
RL Plant Cell Physiol. 46:1674-1681(2005).
RN [9]
RP TISSUE SPECIFICITY.
RX PubMed=19825657; DOI=10.1093/mp/ssp023;
RA Wang J.R., Hu H., Wang G.H., Li J., Chen J.Y., Wu P.;
RT "Expression of PIN genes in rice (Oryza sativa L.): tissue specificity and
RT regulation by hormones.";
RL Mol. Plant 2:823-831(2009).
CC -!- FUNCTION: Acts as a component of the auxin efflux carrier. Seems to be
CC involved in the polar auxin transport which may promote adventitious
CC root emergence and control tillering. {ECO:0000269|PubMed:16085936}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane
CC protein {ECO:0000255}.
CC -!- TISSUE SPECIFICITY: Expressed in vascular tissues of root, stem and
CC leaf. Expressed in anthers, embryo and in the primordia of adventitious
CC and lateral roots (PubMed:16085936). Expressed in roots, stem bases,
CC stems, leaves and young panicles (PubMed:19825657).
CC {ECO:0000269|PubMed:16085936, ECO:0000269|PubMed:19825657}.
CC -!- MISCELLANEOUS: Plants silencing PIN1A exhibit inhibition of the
CC emergence and development of adventitious roots, increased number of
CC tillers and enlarged tiller angles. {ECO:0000269|PubMed:16085936}.
CC -!- SIMILARITY: Belongs to the auxin efflux carrier (TC 2.A.69.1) family.
CC {ECO:0000305}.
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DR EMBL; AF056027; AAC39514.1; -; mRNA.
DR EMBL; AP004800; BAD72497.1; -; Genomic_DNA.
DR EMBL; AP005297; BAD72501.1; -; Genomic_DNA.
DR EMBL; AP008208; BAF10009.1; -; Genomic_DNA.
DR EMBL; AP014958; BAS80873.1; -; Genomic_DNA.
DR EMBL; CM000139; EEE57795.1; -; Genomic_DNA.
DR EMBL; AK102343; BAG95510.1; -; mRNA.
DR EMBL; BR000827; FAA00676.1; -; Genomic_DNA.
DR PIR; T02876; T02876.
DR RefSeq; XP_015627099.1; XM_015771613.1.
DR AlphaFoldDB; Q5SMQ9; -.
DR STRING; 4530.OS02T0743400-01; -.
DR PaxDb; Q5SMQ9; -.
DR PRIDE; Q5SMQ9; -.
DR EnsemblPlants; Os02t0743400-01; Os02t0743400-01; Os02g0743400.
DR GeneID; 4330700; -.
DR Gramene; Os02t0743400-01; Os02t0743400-01; Os02g0743400.
DR KEGG; osa:4330700; -.
DR eggNOG; ENOG502QRM7; Eukaryota.
DR HOGENOM; CLU_019285_1_1_1; -.
DR InParanoid; Q5SMQ9; -.
DR OMA; ICTDSYI; -.
DR OrthoDB; 337723at2759; -.
DR PlantReactome; R-OSA-5608118; Auxin signalling.
DR PlantReactome; R-OSA-8858053; Polar auxin transport.
DR PlantReactome; R-OSA-9627657; Regulation of leaf development.
DR PlantReactome; R-OSA-9639861; Development of root hair.
DR PlantReactome; R-OSA-9675508; Root elongation.
DR Proteomes; UP000000763; Chromosome 2.
DR Proteomes; UP000007752; Chromosome 2.
DR Proteomes; UP000059680; Chromosome 2.
DR Genevisible; Q5SMQ9; OS.
DR GO; GO:0009921; C:auxin efflux carrier complex; IMP:Gramene.
DR GO; GO:0005783; C:endoplasmic reticulum; IBA:GO_Central.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0010329; F:auxin efflux transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0048830; P:adventitious root development; IMP:Gramene.
DR GO; GO:0010315; P:auxin export across the plasma membrane; IBA:GO_Central.
DR GO; GO:0010252; P:auxin homeostasis; IBA:GO_Central.
DR GO; GO:0009926; P:auxin polar transport; IBA:GO_Central.
DR GO; GO:0009734; P:auxin-activated signaling pathway; IMP:Gramene.
DR InterPro; IPR014024; Auxin_eff_plant.
DR InterPro; IPR004776; Mem_trans.
DR Pfam; PF03547; Mem_trans; 1.
DR TIGRFAMs; TIGR00946; 2a69; 1.
PE 2: Evidence at transcript level;
KW Auxin signaling pathway; Glycoprotein; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..595
FT /note="Auxin efflux carrier component 1a"
FT /id="PRO_0000123788"
FT TRANSMEM 7..27
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 39..59
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 71..91
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 101..121
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 132..152
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 456..476
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 480..500
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 517..537
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 541..561
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 575..595
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 281..335
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 404..427
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 211
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 234
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 257
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 595 AA; 64718 MW; 81703D7382CEC2A8 CRC64;
MITAADFYHV MTAMVPLYVA MILAYGSVKW WRIFTPDQCS GINRFVALFA VPLLSFHFIS
TNNPYTMNLR FIAADTLQKL MVLAMLTAWS HLSRRGSLEW TITLFSLSTL PNTLVMGIPL
LKGMYGEFSG SLMVQIVVLQ CIIWYTLMLF MFEYRGARML ITEQFPDTAA NIASIVVDPD
VVSLDGRRDA IETETEVKED GRIHVTVRRS NASRSDIYSR RSMGFSSTTP RPSNLTNAEI
YSLQSSRNPT PRGSSFNHTD FYSMVGRSSN FGAADAFGVR TGATPRPSNY EDDASKPKYP
LPASNAAPMA GHYPAPNPAV SSAPKGAKKA ATNGQAKGED LHMFVWSSSA SPVSDVFGGG
APDYNDAAAV KSPRKMDGAK DREDYVERDD FSFGNRGVMD RDAEAGDEKA AAAAGADPSK
AMAAPTAMPP TSVMTRLILI MVWRKLIRNP NTYSSLIGLI WSLVCFRWNF EMPAIVLKSI
SILSDAGLGM AMFSLGLFMA LQPHIIACGN KVATYAMAVR FLAGPAVMAA ASFAVGLRGT
LLHVAIVQAA LPQGIVPFVF AKEYSVHPSI LSTAVIFGML IALPITLVYY ILLGL
