PIN2_ORYSJ
ID PIN2_ORYSJ Reviewed; 630 AA.
AC Q651V6; Q0DAE1;
DT 10-JAN-2006, integrated into UniProtKB/Swiss-Prot.
DT 25-OCT-2004, sequence version 1.
DT 03-AUG-2022, entry version 97.
DE RecName: Full=Auxin efflux carrier component 2 {ECO:0000305};
DE Short=OsPIN2 {ECO:0000303|PubMed:16085936};
GN Name=PIN2 {ECO:0000303|PubMed:16085936};
GN OrderedLocusNames=Os06g0660200 {ECO:0000312|EMBL:BAS98970.1},
GN LOC_Os06g44970 {ECO:0000305};
GN ORFNames=OSJNBa0051O02.21 {ECO:0000312|EMBL:BAD46411.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [5]
RP IDENTIFICATION, AND TISSUE SPECIFICITY.
RX DOI=10.1016/j.plantsci.2010.02.018;
RA Miyashita Y., Takasugi T., Ito Y.;
RT "Identification and expression analysis of PIN genes in rice.";
RL Plant Sci. 178:424-428(2010).
RN [6]
RP NOMENCLATURE.
RX PubMed=16085936; DOI=10.1093/pcp/pci183;
RA Xu M., Zhu L., Shou H., Wu P.;
RT "A PIN1 family gene, OsPIN1, involved in auxin-dependent adventitious root
RT emergence and tillering in rice.";
RL Plant Cell Physiol. 46:1674-1681(2005).
RN [7]
RP TISSUE SPECIFICITY.
RX PubMed=19825657; DOI=10.1093/mp/ssp023;
RA Wang J.R., Hu H., Wang G.H., Li J., Chen J.Y., Wu P.;
RT "Expression of PIN genes in rice (Oryza sativa L.): tissue specificity and
RT regulation by hormones.";
RL Mol. Plant 2:823-831(2009).
RN [8]
RP FUNCTION.
RX PubMed=21777365; DOI=10.1111/j.1467-7652.2011.00637.x;
RA Chen Y., Fan X., Song W., Zhang Y., Xu G.;
RT "Over-expression of OsPIN2 leads to increased tiller numbers, angle and
RT shorter plant height through suppression of OsLAZY1.";
RL Plant Biotechnol. J. 10:139-149(2012).
CC -!- FUNCTION: Acts as a component of the auxin efflux carrier. Involved in
CC the basipetal polar auxin transport which contributes to the spreading
CC growth of the tillers. {ECO:0000269|PubMed:21777365}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane
CC protein {ECO:0000255}.
CC -!- TISSUE SPECIFICITY: Expressed in roots, leaves, shoot apex and panicles
CC (Ref.5). Expressed in roots, stem bases and young panicles
CC (PubMed:19825657). {ECO:0000269|PubMed:19825657, ECO:0000269|Ref.5}.
CC -!- MISCELLANEOUS: Plants over-expressing PIN2 exhibit reduced height,
CC increased tiller number and enlarged tiller angle.
CC {ECO:0000269|PubMed:21777365}.
CC -!- SIMILARITY: Belongs to the auxin efflux carrier (TC 2.A.69.1) family.
CC {ECO:0000305}.
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DR EMBL; AP005769; BAD46411.1; -; Genomic_DNA.
DR EMBL; AP008212; BAF20182.1; -; Genomic_DNA.
DR EMBL; AP014962; BAS98970.1; -; Genomic_DNA.
DR EMBL; AK101191; BAG94949.1; -; mRNA.
DR EMBL; BR000831; FAA00680.1; -; Genomic_DNA.
DR RefSeq; XP_015641653.1; XM_015786167.1.
DR AlphaFoldDB; Q651V6; -.
DR STRING; 4530.OS06T0660200-01; -.
DR PaxDb; Q651V6; -.
DR PRIDE; Q651V6; -.
DR EnsemblPlants; Os06t0660200-01; Os06t0660200-01; Os06g0660200.
DR GeneID; 4341736; -.
DR Gramene; Os06t0660200-01; Os06t0660200-01; Os06g0660200.
DR KEGG; osa:4341736; -.
DR eggNOG; ENOG502QV64; Eukaryota.
DR HOGENOM; CLU_019285_1_1_1; -.
DR InParanoid; Q651V6; -.
DR OMA; NFDEEMM; -.
DR OrthoDB; 337723at2759; -.
DR PlantReactome; R-OSA-8858053; Polar auxin transport.
DR PlantReactome; R-OSA-9639861; Development of root hair.
DR PlantReactome; R-OSA-9675508; Root elongation.
DR Proteomes; UP000000763; Chromosome 6.
DR Proteomes; UP000059680; Chromosome 6.
DR Genevisible; Q651V6; OS.
DR GO; GO:0009921; C:auxin efflux carrier complex; IDA:UniProtKB.
DR GO; GO:0005783; C:endoplasmic reticulum; IBA:GO_Central.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0010329; F:auxin efflux transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0010315; P:auxin export across the plasma membrane; IBA:GO_Central.
DR GO; GO:0010252; P:auxin homeostasis; IBA:GO_Central.
DR GO; GO:0009926; P:auxin polar transport; IMP:UniProtKB.
DR GO; GO:0009734; P:auxin-activated signaling pathway; IEA:UniProtKB-KW.
DR InterPro; IPR014024; Auxin_eff_plant.
DR InterPro; IPR004776; Mem_trans.
DR InterPro; IPR033526; PIN2.
DR PANTHER; PTHR31752:SF4; PTHR31752:SF4; 1.
DR Pfam; PF03547; Mem_trans; 1.
DR TIGRFAMs; TIGR00946; 2a69; 1.
PE 2: Evidence at transcript level;
KW Auxin signaling pathway; Glycoprotein; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..630
FT /note="Auxin efflux carrier component 2"
FT /id="PRO_0000123791"
FT TRANSMEM 7..27
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 39..59
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 71..91
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 109..129
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 140..160
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 491..511
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 515..535
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 550..570
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 575..595
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 610..630
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 317..350
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 251
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 630 AA; 66615 MW; 23D62E597A125E3B CRC64;
MITGRDIYDV LAAIVPLYVA MFLAYGSVRW WGIFTPDQCS GINRFVAVFA VPLLSFHFIS
TNDPYSMNYR FLAADSLQKL VILAALAVWH NLLSRYRRNG GAAASLDWTI TLFSLSTLPN
TLVMGIPLLR AMYGDFSGSL MVQIVVLQSV IWYTLMLFLF EYRGAKALIS EQFPPDVGAS
IASFRVDSDV VSLNGREALQ ADAEVGRDGR VHVVIRRSAS ASTTGGGGGA ARSGVSRAYG
ASNAMTPRAS NLTGVEIYSL QTSREPTPRA SSFNQADFYA MFSGSKMASQ MASPMAQHGG
AGGRAQGLDE QVTNKFASGK AADPPSYPAP NPGMMPAPRK KELGGSNSNS NKELHMFVWS
SSASPVSEAN LRNAVNHAAS TDFASAPPPA AVPVGGATPK GVSGSVTPAA KNGGGELEIE
DGLKSPAAGL AAKFPVSGSP YVAPRKKGGG ADVPGLAEAA HPMPPTSVMT RLILIMVWRK
LIRNPNTYSS LIGLVWSLVS FRWNIQMPSI IKGSISILSD AGLGMAMFSL GLFMALQPKI
ISCGKTVATF AMAVRFLTGP AVIAATSIAI GLRGVLLHVA IVQAALPQGI VPFVFAKEYN
CHPQILSTAV IFGMLIALPI TILYYVLLGI
