ID   PIN8_ORYSJ              Reviewed;         311 AA.
AC   Q0JJV0; A0A0P0V7D1; A2ZX80;
DT   05-OCT-2016, integrated into UniProtKB/Swiss-Prot.
DT   13-OCT-2009, sequence version 2.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=Probable auxin efflux carrier component 8 {ECO:0000305};
DE            Short=OsPIN8 {ECO:0000303|Ref.5};
GN   Name=PIN8;
GN   OrderedLocusNames=Os01g0715600 {ECO:0000312|EMBL:BAF05978.2},
GN   LOC_Os01g51780 {ECO:0000305};
GN   ORFNames=OsJ_03248 {ECO:0000312|EMBL:EAZ13327.1};
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
RN   [5]
RP   IDENTIFICATION, AND TISSUE SPECIFICITY.
RX   DOI=10.1016/j.plantsci.2010.02.018;
RA   Miyashita Y., Takasugi T., Ito Y.;
RT   "Identification and expression analysis of PIN genes in rice.";
RL   Plant Sci. 178:424-428(2010).
CC   -!- FUNCTION: May act as a component of the auxin efflux carrier.
CC       {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane
CC       protein {ECO:0000255}.
CC   -!- TISSUE SPECIFICITY: Expressed in shoot apex and panicles.
CC       {ECO:0000269|Ref.5}.
CC   -!- SIMILARITY: Belongs to the auxin efflux carrier (TC 2.A.69.1) family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAS74026.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AP008207; BAF05978.2; -; Genomic_DNA.
DR   EMBL; AP014957; BAS74026.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CM000138; EAZ13327.1; -; Genomic_DNA.
DR   EMBL; BR000837; FAA00686.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q0JJV0; -.
DR   STRING; 39947.Q0JJV0; -.
DR   PRIDE; Q0JJV0; -.
DR   InParanoid; Q0JJV0; -.
DR   PlantReactome; R-OSA-8858053; Polar auxin transport.
DR   PlantReactome; R-OSA-8868949; Intracellular auxin transport.
DR   Proteomes; UP000000763; Chromosome 1.
DR   Proteomes; UP000007752; Chromosome 1.
DR   Proteomes; UP000059680; Chromosome 1.
DR   GO; GO:0005783; C:endoplasmic reticulum; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0010329; F:auxin efflux transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0010315; P:auxin export across the plasma membrane; IBA:GO_Central.
DR   GO; GO:0010252; P:auxin homeostasis; IBA:GO_Central.
DR   GO; GO:0009926; P:auxin polar transport; IBA:GO_Central.
DR   GO; GO:0009734; P:auxin-activated signaling pathway; IEA:UniProtKB-KW.
DR   InterPro; IPR004776; Mem_trans.
DR   Pfam; PF03547; Mem_trans; 2.
PE   2: Evidence at transcript level;
KW   Auxin signaling pathway; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..311
FT                   /note="Probable auxin efflux carrier component 8"
FT                   /id="PRO_0000437478"
FT   TRANSMEM        7..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        39..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        69..89
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        101..121
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        132..152
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        168..188
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        192..212
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        227..247
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        252..272
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        287..307
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   311 AA;  34120 MW;  AE60F561A3EA9957 CRC64;
     MVSWKDIYLV LEATVPLYVA MILAYLSIKW WKLFTPEQCS GINKFVAKFS IPLLSFQVIS
     TTDPYDMNIK LIYSDILQKS LALLGFAAIS KACCAEKFDW LITGFSLSTL PNTLIVGIPL
     LKGMYGEQAG KLLSQIVVLQ SLIWYTLLLF LFELRAANGM ATTTSSETTG LIWALVGFRW
     HIRLPLIVSN SIRMLSDGGL GMAMFSLGLF TALQTKIIAC GAKRMLLALA IRFFLGPALM
     GMSSYAIGMR GVLLKIAIVQ AALPQGIVPF VFAKEYNVQA DILSTAIIVG MMVAVPVALA
     YYFAMIIPAI K