PINR_ECOLI
ID PINR_ECOLI Reviewed; 196 AA.
AC P0ADI0; P77574;
DT 06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 06-DEC-2005, sequence version 1.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=Serine recombinase PinR {ECO:0000250|UniProtKB:P03015};
DE EC=3.1.22.-;
DE EC=6.5.1.-;
DE AltName: Full=DNA-invertase PinR {ECO:0000305};
DE AltName: Full=Putative DNA-invertase from lambdoid prophage Rac;
DE AltName: Full=Site-specific recombinase PinR {ECO:0000305};
GN Name=pinR; Synonyms=ynaD; OrderedLocusNames=b1374, JW1368;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=9097039; DOI=10.1093/dnares/3.6.363;
RA Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T.,
RA Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K.,
RA Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S.,
RA Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G.,
RA Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y.,
RA Wada C., Yamamoto Y., Horiuchi T.;
RT "A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 28.0-40.1 min region on the linkage map.";
RL DNA Res. 3:363-377(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
CC -!- INTERACTION:
CC P0ADI0; P06959: aceF; NbExp=3; IntAct=EBI-544672, EBI-542707;
CC -!- SIMILARITY: Belongs to the site-specific recombinase resolvase family.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; U00096; AAC74456.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA14979.1; -; Genomic_DNA.
DR PIR; A64888; A64888.
DR RefSeq; NP_415892.1; NC_000913.3.
DR RefSeq; WP_000086527.1; NZ_SSUU01000015.1.
DR AlphaFoldDB; P0ADI0; -.
DR SMR; P0ADI0; -.
DR BioGRID; 4263521; 165.
DR DIP; DIP-47969N; -.
DR IntAct; P0ADI0; 9.
DR STRING; 511145.b1374; -.
DR PaxDb; P0ADI0; -.
DR PRIDE; P0ADI0; -.
DR EnsemblBacteria; AAC74456; AAC74456; b1374.
DR EnsemblBacteria; BAA14979; BAA14979; BAA14979.
DR GeneID; 67414592; -.
DR GeneID; 948973; -.
DR KEGG; ecj:JW1368; -.
DR KEGG; eco:b1374; -.
DR PATRIC; fig|511145.12.peg.1435; -.
DR EchoBASE; EB3154; -.
DR eggNOG; COG1961; Bacteria.
DR HOGENOM; CLU_010686_8_2_6; -.
DR InParanoid; P0ADI0; -.
DR OMA; EQIRFAY; -.
DR PhylomeDB; P0ADI0; -.
DR BioCyc; EcoCyc:G6697-MON; -.
DR PRO; PR:P0ADI0; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000150; F:DNA strand exchange activity; IBA:GO_Central.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IBA:GO_Central.
DR Gene3D; 3.40.50.1390; -; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR006118; Recombinase_CS.
DR InterPro; IPR006119; Resolv_N.
DR InterPro; IPR036162; Resolvase-like_N_sf.
DR InterPro; IPR006120; Resolvase_HTH_dom.
DR Pfam; PF02796; HTH_7; 1.
DR Pfam; PF00239; Resolvase; 1.
DR SMART; SM00857; Resolvase; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR SUPFAM; SSF53041; SSF53041; 1.
DR PROSITE; PS00398; RECOMBINASES_2; 1.
DR PROSITE; PS51736; RECOMBINASES_3; 1.
PE 1: Evidence at protein level;
KW DNA integration; DNA invertase; DNA recombination; DNA-binding; Hydrolase;
KW Ligase; Reference proteome.
FT CHAIN 1..196
FT /note="Serine recombinase PinR"
FT /id="PRO_0000196363"
FT DOMAIN 3..143
FT /note="Resolvase/invertase-type recombinase catalytic"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01072"
FT ACT_SITE 11
FT /note="O-(5'-phospho-DNA)-serine intermediate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01072"
SQ SEQUENCE 196 AA; 21908 MW; 643A62BC940B29A9 CRC64;
MSRIFAYCRI STLDQTTENQ RREIESAGFK IKPQQIIEEH ISGSAATSER PGFNRLLARL
KCGDQLIVTK LDRLGCNAMD IRKTVEQLTE TGIRVHCLAL GGIDLTSPTG KMMMQVISAV
AEFERDLLLE RTHSGIVRAR GAGKRFGRPP VLNEEQKQVV FERIKSGVSI SAIAREFKTS
RQTILRAKAK LQTPDI
