PIP22_ORYSJ
ID PIP22_ORYSJ Reviewed; 288 AA.
AC Q6K215; B7E6W2; Q0DZD3;
DT 22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=Probable aquaporin PIP2-2;
DE AltName: Full=OsPIP2;2;
DE AltName: Full=Plasma membrane intrinsic protein 2-2;
GN Name=PIP2-2; OrderedLocusNames=Os02g0629200, LOC_Os02g41860;
GN ORFNames=B1469H02.22-1;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [5]
RP NOMENCLATURE, TISSUE SPECIFICITY, AND INDUCTION.
RX PubMed=16033806; DOI=10.1093/pcp/pci172;
RA Sakurai J., Ishikawa F., Yamaguchi T., Uemura M., Maeshima M.;
RT "Identification of 33 rice aquaporin genes and analysis of their expression
RT and function.";
RL Plant Cell Physiol. 46:1568-1577(2005).
CC -!- FUNCTION: Aquaporins facilitate the transport of water and small
CC neutral solutes across cell membranes. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Expressed in roots, leaves and anthers.
CC {ECO:0000269|PubMed:16033806}.
CC -!- INDUCTION: Down-regulated by chilling. {ECO:0000269|PubMed:16033806}.
CC -!- DOMAIN: Aquaporins contain two tandem repeats each containing three
CC membrane-spanning domains and a pore-forming loop with the signature
CC motif Asn-Pro-Ala (NPA).
CC -!- SIMILARITY: Belongs to the MIP/aquaporin (TC 1.A.8) family. PIP (TC
CC 1.A.8.11) subfamily. {ECO:0000305}.
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DR EMBL; AP006168; BAD23735.1; -; Genomic_DNA.
DR EMBL; AP008208; BAF09405.1; -; Genomic_DNA.
DR EMBL; AP014958; BAS79886.1; -; Genomic_DNA.
DR EMBL; AK061782; BAG88109.1; -; mRNA.
DR RefSeq; XP_015626399.1; XM_015770913.1.
DR AlphaFoldDB; Q6K215; -.
DR SMR; Q6K215; -.
DR STRING; 4530.OS02T0629200-02; -.
DR PaxDb; Q6K215; -.
DR PRIDE; Q6K215; -.
DR EnsemblPlants; Os02t0629200-02; Os02t0629200-02; Os02g0629200.
DR GeneID; 4330049; -.
DR Gramene; Os02t0629200-02; Os02t0629200-02; Os02g0629200.
DR KEGG; osa:4330049; -.
DR eggNOG; KOG0223; Eukaryota.
DR HOGENOM; CLU_020019_3_0_1; -.
DR InParanoid; Q6K215; -.
DR OMA; IVYGVKP; -.
DR OrthoDB; 1152704at2759; -.
DR Proteomes; UP000000763; Chromosome 2.
DR Proteomes; UP000059680; Chromosome 2.
DR ExpressionAtlas; Q6K215; baseline and differential.
DR Genevisible; Q6K215; OS.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0015250; F:water channel activity; IBA:GO_Central.
DR CDD; cd00333; MIP; 1.
DR Gene3D; 1.20.1080.10; -; 1.
DR InterPro; IPR023271; Aquaporin-like.
DR InterPro; IPR034294; Aquaporin_transptr.
DR InterPro; IPR000425; MIP.
DR InterPro; IPR022357; MIP_CS.
DR PANTHER; PTHR45687; PTHR45687; 1.
DR Pfam; PF00230; MIP; 1.
DR PRINTS; PR00783; MINTRINSICP.
DR SUPFAM; SSF81338; SSF81338; 1.
DR TIGRFAMs; TIGR00861; MIP; 1.
DR PROSITE; PS00221; MIP; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Membrane; Reference proteome; Repeat; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..288
FT /note="Probable aquaporin PIP2-2"
FT /id="PRO_0000064035"
FT TRANSMEM 42..62
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TRANSMEM 81..101
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TRANSMEM 130..150
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TRANSMEM 172..192
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TRANSMEM 204..224
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TRANSMEM 254..274
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 111..113
FT /note="NPA 1"
FT MOTIF 232..234
FT /note="NPA 2"
SQ SEQUENCE 288 AA; 30498 MW; C2FAA11B6090364E CRC64;
MAKDIEASAP EGGEFSAKDY TDPPPAPLID VEELTKWSLY RAVIAEFIAT LLFLYITVAT
VIGYKHQSDA TVNTTDAACS GVGILGIAWA FGGMIFILVY CTAGISGGHI NPAVTFGLFL
ARKVSLIRAV LYIIAQCLGA ICGVGLVKGF QSSYYARYGG GANELSDGYS KGTGLGAEII
GTFVLVYTVF SATDPKRNAR DSHIPVLAPL PIGFAVFMVH LATIPITGTG INPARSLGTA
VIYNKDKAWD DQWIFWVGPL IGAAIAAAYH QYVLRASAAK LGSYRSNA
