PIP24_ORYSJ
ID PIP24_ORYSJ Reviewed; 286 AA.
AC Q8GRT8; B7EL23; Q0D6R7;
DT 22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 130.
DE RecName: Full=Aquaporin PIP2-4;
DE AltName: Full=OsPIP2;4;
DE AltName: Full=Plasma membrane intrinsic protein 2-4;
GN Name=PIP2-4; OrderedLocusNames=Os07g0448100, LOC_Os07g26630;
GN ORFNames=OJ1047_A06.105, P0475E07.131;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [5]
RP NOMENCLATURE, FUNCTION, TISSUE SPECIFICITY, AND INDUCTION.
RX PubMed=16033806; DOI=10.1093/pcp/pci172;
RA Sakurai J., Ishikawa F., Yamaguchi T., Uemura M., Maeshima M.;
RT "Identification of 33 rice aquaporin genes and analysis of their expression
RT and function.";
RL Plant Cell Physiol. 46:1568-1577(2005).
CC -!- FUNCTION: Water channel required to facilitate the transport of water
CC across cell membrane. May play a role in root water uptake.
CC {ECO:0000269|PubMed:16033806}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Expressed in roots. {ECO:0000269|PubMed:16033806}.
CC -!- INDUCTION: Circadian-regulation. Expression is higher during the light
CC phase than during the dark phase. Down-regulated by chilling.
CC {ECO:0000269|PubMed:16033806}.
CC -!- DOMAIN: Aquaporins contain two tandem repeats each containing three
CC membrane-spanning domains and a pore-forming loop with the signature
CC motif Asn-Pro-Ala (NPA).
CC -!- SIMILARITY: Belongs to the MIP/aquaporin (TC 1.A.8) family. PIP (TC
CC 1.A.8.11) subfamily. {ECO:0000305}.
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DR EMBL; AP003802; BAC15860.1; -; Genomic_DNA.
DR EMBL; AP004668; BAC16113.1; -; Genomic_DNA.
DR EMBL; AP008213; BAF21456.1; -; Genomic_DNA.
DR EMBL; AP014963; BAT01301.1; -; Genomic_DNA.
DR EMBL; AK072632; BAG93070.1; -; mRNA.
DR RefSeq; XP_015644586.1; XM_015789100.1.
DR AlphaFoldDB; Q8GRT8; -.
DR SMR; Q8GRT8; -.
DR STRING; 4530.OS07T0448100-01; -.
DR PaxDb; Q8GRT8; -.
DR PRIDE; Q8GRT8; -.
DR EnsemblPlants; Os07t0448100-01; Os07t0448100-01; Os07g0448100.
DR GeneID; 4343119; -.
DR Gramene; Os07t0448100-01; Os07t0448100-01; Os07g0448100.
DR KEGG; osa:4343119; -.
DR eggNOG; KOG0223; Eukaryota.
DR HOGENOM; CLU_020019_3_0_1; -.
DR InParanoid; Q8GRT8; -.
DR OMA; LRKWSFY; -.
DR OrthoDB; 1152704at2759; -.
DR PlantReactome; R-OSA-9618218; Arsenic uptake and detoxification.
DR Proteomes; UP000000763; Chromosome 7.
DR Proteomes; UP000059680; Chromosome 7.
DR Genevisible; Q8GRT8; OS.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0015250; F:water channel activity; IBA:GO_Central.
DR CDD; cd00333; MIP; 1.
DR Gene3D; 1.20.1080.10; -; 1.
DR InterPro; IPR023271; Aquaporin-like.
DR InterPro; IPR034294; Aquaporin_transptr.
DR InterPro; IPR000425; MIP.
DR InterPro; IPR022357; MIP_CS.
DR PANTHER; PTHR45687; PTHR45687; 1.
DR Pfam; PF00230; MIP; 1.
DR PRINTS; PR00783; MINTRINSICP.
DR SUPFAM; SSF81338; SSF81338; 1.
DR TIGRFAMs; TIGR00861; MIP; 1.
DR PROSITE; PS00221; MIP; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Membrane; Reference proteome; Repeat; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..286
FT /note="Aquaporin PIP2-4"
FT /id="PRO_0000064037"
FT TRANSMEM 40..60
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TRANSMEM 77..97
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TRANSMEM 128..148
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TRANSMEM 170..190
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TRANSMEM 204..224
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TRANSMEM 252..272
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT MOTIF 109..111
FT /note="NPA 1"
FT MOTIF 230..232
FT /note="NPA 2"
SQ SEQUENCE 286 AA; 29936 MW; BB335986156C6B0B CRC64;
MGKEVDVSTL EAGGARDYID PPPAPLVDVD ELGKWSLYRA LIAEFVATLL FLYVTVATVI
GYKHQTDAAV NGADAACGGV GVLGIAWAFG GMIFILVYCT AGVSGGHINP AVTLGLFLAR
KVSLVRALLY MAAQCLGAIC GVALVKGFQS SLYDRYGGGA NELAAGYSTG TGLAAEIIGT
FVLVYTVFSA TDPKRNARDS HVPVLAPLPI GFAVFMVHLA TIPITGTGIN PARSLGVAVV
YNNNKAWSDQ WIFWVGPFIG AAIAALYHQV ILRASARGYG SFRSNA
