ID   PIP_PONPY               Reviewed;         146 AA.
AC   A0A888;
DT   23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   28-NOV-2006, sequence version 1.
DT   25-MAY-2022, entry version 42.
DE   RecName: Full=Prolactin-inducible protein homolog;
DE   AltName: Full=Prolactin-induced protein;
DE   Flags: Precursor;
GN   Name=PIP;
OS   Pongo pygmaeus (Bornean orangutan).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9600;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Isolate T039;
RX   PubMed=16949771; DOI=10.1016/j.gene.2006.07.014;
RA   Kitano T., Tian W., Umetsu K., Yuasa I., Yamazaki K., Saitou N., Osawa M.;
RT   "Origin and evolution of gene for prolactin-induced protein.";
RL   Gene 383:64-70(2006).
CC   -!- SUBUNIT: Monomer. Interacts with AZGP1 (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the PIP family. {ECO:0000305}.
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DR   EMBL; AB251904; BAF35624.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A888; -.
DR   SMR; A0A888; -.
DR   PRIDE; A0A888; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR007990; PIP.
DR   PANTHER; PTHR15096; PTHR15096; 1.
DR   Pfam; PF05326; SVA; 1.
DR   PIRSF; PIRSF002572; PIP-GCDFP-15; 1.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Disulfide bond; Glycoprotein; Pyrrolidone carboxylic acid; Secreted;
KW   Signal.
FT   SIGNAL          1..28
FT                   /evidence="ECO:0000250"
FT   CHAIN           29..146
FT                   /note="Prolactin-inducible protein homolog"
FT                   /id="PRO_0000273197"
FT   MOD_RES         29
FT                   /note="Pyrrolidone carboxylic acid"
FT                   /evidence="ECO:0000250|UniProtKB:P12273"
FT   CARBOHYD        105
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        65..91
FT                   /evidence="ECO:0000250"
FT   DISULFID        89..123
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   146 AA;  16546 MW;  DE8102B04D88088B CRC64;
     MHLLQLLFRA SPATLLLVLC LQLGANKAQD NTRKIIIKDF DIPKSVRPND EVTAVLAVQT
     ELKECMVIKT YLISSVPLEG AFNYKYTACL CDENPKTFYW DFYTNRTVQI AAVVDVIREL
     GICPDDAAVI PIKNNRFYTT ETLEVE