ID   PIRL3_ORYSJ             Reviewed;         446 AA.
AC   Q7XK44; Q0JCE1;
DT   16-OCT-2013, integrated into UniProtKB/Swiss-Prot.
DT   16-OCT-2013, sequence version 3.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=Plant intracellular Ras-group-related LRR protein 3;
DE   AltName: Full=Intracellular Ras-group-related LRR protein 3;
DE            Short=OsIRL3;
GN   Name=IRL3; OrderedLocusNames=Os04g0476700, LOC_Os04g40080;
GN   ORFNames=OSJNBa0044K18.1;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12447439; DOI=10.1038/nature01183;
RA   Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y.,
RA   Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q.,
RA   Zhang L., Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T.,
RA   Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R.,
RA   Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G.,
RA   Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C.,
RA   Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J.,
RA   Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J.,
RA   Li J., Hong G., Xue Y., Han B.;
RT   "Sequence and analysis of rice chromosome 4.";
RL   Nature 420:316-320(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 176-446.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12869764; DOI=10.1126/science.1081288;
RG   The rice full-length cDNA consortium;
RT   "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT   japonica rice.";
RL   Science 301:376-379(2003).
RN   [6]
RP   GENE FAMILY, MOTIF GVYW, TISSUE SPECIFICITY, AND DISRUPTION PHENOTYPE.
RX   PubMed=20949308; DOI=10.1007/s11103-010-9704-6;
RA   You C., Dai X., Li X., Wang L., Chen G., Xiao J., Wu C.;
RT   "Molecular characterization, expression pattern, and functional analysis of
RT   the OsIRL gene family encoding intracellular Ras-group-related LRR proteins
RT   in rice.";
RL   Plant Mol. Biol. 74:617-629(2010).
CC   -!- FUNCTION: Leucine-rich repeat protein that likely mediates protein
CC       interactions, possibly in the context of signal transduction.
CC       {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:20949308}.
CC   -!- DISRUPTION PHENOTYPE: No visible phenotype.
CC       {ECO:0000269|PubMed:20949308}.
CC   -!- SIMILARITY: Belongs to the SHOC2 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAF14996.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=CAE05859.2; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AL606595; CAE05859.2; ALT_INIT; Genomic_DNA.
DR   EMBL; AP008210; BAF14996.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP014960; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AK071870; -; NOT_ANNOTATED_CDS; mRNA.
DR   AlphaFoldDB; Q7XK44; -.
DR   SMR; Q7XK44; -.
DR   STRING; 4530.OS04T0476700-01; -.
DR   PaxDb; Q7XK44; -.
DR   PRIDE; Q7XK44; -.
DR   eggNOG; KOG0619; Eukaryota.
DR   HOGENOM; CLU_000288_18_15_1; -.
DR   InParanoid; Q7XK44; -.
DR   Proteomes; UP000000763; Chromosome 4.
DR   Proteomes; UP000059680; Chromosome 4.
DR   Genevisible; Q7XK44; OS.
DR   Gene3D; 3.80.10.10; -; 1.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   Pfam; PF00560; LRR_1; 1.
DR   Pfam; PF13855; LRR_8; 2.
DR   SMART; SM00369; LRR_TYP; 7.
DR   PROSITE; PS51450; LRR; 8.
PE   2: Evidence at transcript level;
KW   Coiled coil; Leucine-rich repeat; Reference proteome; Repeat.
FT   CHAIN           1..446
FT                   /note="Plant intracellular Ras-group-related LRR protein 3"
FT                   /id="PRO_0000423612"
FT   REPEAT          138..160
FT                   /note="LRR 1"
FT   REPEAT          161..184
FT                   /note="LRR 2"
FT   REPEAT          185..207
FT                   /note="LRR 3"
FT   REPEAT          208..230
FT                   /note="LRR 4"
FT   REPEAT          232..254
FT                   /note="LRR 5"
FT   REPEAT          255..277
FT                   /note="LRR 6"
FT   REPEAT          279..300
FT                   /note="LRR 7"
FT   REPEAT          301..324
FT                   /note="LRR 8"
FT   REPEAT          325..347
FT                   /note="LRR 9"
FT   REPEAT          349..371
FT                   /note="LRR 10"
FT   REGION          101..121
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          65..100
FT                   /evidence="ECO:0000255"
FT   MOTIF           372..384
FT                   /note="GVYW"
FT   COMPBIAS        101..115
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   446 AA;  49004 MW;  9F7DEB5B0F16B8A5 CRC64;
     MPGLRHPSVL RAMTRAVADV SAARSALQVL GPRPDHELVD SSRAIVAATD AEAGGSRRVP
     EGDLEACRAV VRLEETHDAY EALLQEAEGR LEAVYRSAME GKDLEEPDGR DESAAAAAGD
     DAAVQEEVIA VLRQAEEGKP VESVRLVDRQ LRHLPEAFGR IQGLRVLDVS RNQLEVIPDA
     IGGLDHLEEL RLASNALISL PDSIGLLLNL RILNVGSNRL RSLPDSISKC RSLIELDASY
     NGLAYLPTNI GYELVNLRKL WVHMNKLRSL PSSICEMRSL YLLDAHFNEL CGLPSAIGKL
     SSLEILNLSS NFSDLKDLPA SFGDLLNLRE LDLSNNQIHA LPDNFGRLDK LEKLNLEQNP
     LSMPPMEIVN KGVDAVKEYM LQRWLDILLE EERKSIAAAE SPQAPTTPSA WLARSVSWVS
     DVSGSLVGYL SGENKTEKDA YLDQQY