ID   PIRL6_ARATH             Reviewed;         380 AA.
AC   O64566;
DT   16-OCT-2013, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   03-AUG-2022, entry version 137.
DE   RecName: Full=Plant intracellular Ras-group-related LRR protein 6;
GN   Name=PIRL6; OrderedLocusNames=At2g19330; ORFNames=F27F23.13;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], GENE FAMILY, MOTIF GVYW, AND TISSUE
RP   SPECIFICITY.
RX   PubMed=15809230; DOI=10.1093/pcp/pci097;
RA   Forsthoefel N.R., Cutler K., Port M.D., Yamamoto T., Vernon D.M.;
RT   "PIRLs: a novel class of plant intracellular leucine-rich repeat
RT   proteins.";
RL   Plant Cell Physiol. 46:913-922(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
CC   -!- FUNCTION: Leucine-rich repeat protein that likely mediates protein
CC       interactions, possibly in the context of signal transduction.
CC       {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:15809230}.
CC   -!- SIMILARITY: Belongs to the SHOC2 family. {ECO:0000305}.
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DR   EMBL; AY849576; AAW57415.1; -; mRNA.
DR   EMBL; AC003058; AAC16463.1; -; Genomic_DNA.
DR   EMBL; CP002685; AEC06869.1; -; Genomic_DNA.
DR   PIR; T01281; T01281.
DR   RefSeq; NP_179523.1; NM_127490.2.
DR   AlphaFoldDB; O64566; -.
DR   SMR; O64566; -.
DR   STRING; 3702.AT2G19330.1; -.
DR   iPTMnet; O64566; -.
DR   PaxDb; O64566; -.
DR   PRIDE; O64566; -.
DR   ProteomicsDB; 235024; -.
DR   EnsemblPlants; AT2G19330.1; AT2G19330.1; AT2G19330.
DR   GeneID; 816450; -.
DR   Gramene; AT2G19330.1; AT2G19330.1; AT2G19330.
DR   KEGG; ath:AT2G19330; -.
DR   Araport; AT2G19330; -.
DR   TAIR; locus:2047595; AT2G19330.
DR   eggNOG; KOG0619; Eukaryota.
DR   HOGENOM; CLU_000288_18_0_1; -.
DR   InParanoid; O64566; -.
DR   OMA; FVQIPLC; -.
DR   OrthoDB; 1382533at2759; -.
DR   PhylomeDB; O64566; -.
DR   PRO; PR:O64566; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; O64566; baseline and differential.
DR   Genevisible; O64566; AT.
DR   Gene3D; 3.80.10.10; -; 2.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   Pfam; PF13855; LRR_8; 2.
DR   SMART; SM00369; LRR_TYP; 7.
DR   PROSITE; PS51450; LRR; 10.
PE   2: Evidence at transcript level;
KW   Leucine-rich repeat; Reference proteome; Repeat.
FT   CHAIN           1..380
FT                   /note="Plant intracellular Ras-group-related LRR protein 6"
FT                   /id="PRO_0000423606"
FT   REPEAT          59..82
FT                   /note="LRR 1"
FT   REPEAT          83..105
FT                   /note="LRR 2"
FT   REPEAT          107..129
FT                   /note="LRR 3"
FT   REPEAT          130..152
FT                   /note="LRR 4"
FT   REPEAT          154..176
FT                   /note="LRR 5"
FT   REPEAT          177..199
FT                   /note="LRR 6"
FT   REPEAT          201..222
FT                   /note="LRR 7"
FT   REPEAT          223..247
FT                   /note="LRR 8"
FT   REPEAT          248..271
FT                   /note="LRR 9"
FT   REPEAT          273..293
FT                   /note="LRR 10"
FT   REGION          1..57
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           298..301
FT                   /note="GVYW; degenerate"
SQ   SEQUENCE   380 AA;  42811 MW;  1385E44B3CC194B7 CRC64;
     MICEEAYHQQ PQIQKEQMMT MDQRNNHQRK RSPLSSPSSP SSPSSPSSPK SPSFNNNEEE
     RLEVVNLSGM ALESLPNPSL NLAQICKLDL SNNHLQTIPE SLTARLLNLI ALDVHSNQIK
     ALPNSIGCLS KLKTLNVSGN FLVSFPKSIQ HCRSLEELNA NFNKLIRLPD SIGFELTNLR
     KLSINSNKLI SLPISITHLT SLRVLDARLN CLMILPDDLE NLINLEILNV SQNFQYLSAL
     PSSIGLLMNL IELDVSYNKI TVLPESIGCM RRLRKLSVEG NPLVSPPIEV MEQNLQVVRE
     YLTQKMNGGS PRSPSKKKSW GFGKLVKYGT FNGGSRSWNR EEREGFIMPE YRSIDSLASP
     RYSGMFSPRR LFSPRTYFSR