PIRL8_ORYSJ
ID PIRL8_ORYSJ Reviewed; 378 AA.
AC Q7XDQ7; Q337P4;
DT 16-OCT-2013, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2003, sequence version 1.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=Plant intracellular Ras-group-related LRR protein 8;
DE AltName: Full=Intracellular Ras-group-related LRR protein 8;
DE Short=OsIRL8;
GN Name=IRL8; OrderedLocusNames=Os10g0456200, LOC_Os10g31790;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12791992; DOI=10.1126/science.1083523;
RA Yu Y., Rambo T., Currie J., Saski C., Kim H.-R., Collura K., Thompson S.,
RA Simmons J., Yang T.-J., Nah G., Patel A.J., Thurmond S., Henry D.,
RA Oates R., Palmer M., Pries G., Gibson J., Anderson H., Paradkar M.,
RA Crane L., Dale J., Carver M.B., Wood T., Frisch D., Engler F.,
RA Soderlund C., Palmer L.E., Teytelman L., Nascimento L., De la Bastide M.,
RA Spiegel L., Ware D., O'Shaughnessy A., Dike S., Dedhia N., Preston R.,
RA Huang E., Ferraro K., Kuit K., Miller B., Zutavern T., Katzenberger F.,
RA Muller S., Balija V., Martienssen R.A., Stein L., Minx P., Johnson D.,
RA Cordum H., Mardis E., Cheng Z., Jiang J., Wilson R., McCombie W.R.,
RA Wing R.A., Yuan Q., Ouyang S., Liu J., Jones K.M., Gansberger K.,
RA Moffat K., Hill J., Tsitrin T., Overton L., Bera J., Kim M., Jin S.,
RA Tallon L., Ciecko A., Pai G., Van Aken S., Utterback T., Reidmuller S.,
RA Bormann J., Feldblyum T., Hsiao J., Zismann V., Blunt S., de Vazeille A.R.,
RA Shaffer T., Koo H., Suh B., Yang Q., Haas B., Peterson J., Pertea M.,
RA Volfovsky N., Wortman J., White O., Salzberg S.L., Fraser C.M., Buell C.R.,
RA Messing J., Song R., Fuks G., Llaca V., Kovchak S., Young S., Bowers J.E.,
RA Paterson A.H., Johns M.A., Mao L., Pan H., Dean R.A.;
RT "In-depth view of structure, activity, and evolution of rice chromosome
RT 10.";
RL Science 300:1566-1569(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP GENE FAMILY, TISSUE SPECIFICITY, AND DISRUPTION PHENOTYPE.
RX PubMed=20949308; DOI=10.1007/s11103-010-9704-6;
RA You C., Dai X., Li X., Wang L., Chen G., Xiao J., Wu C.;
RT "Molecular characterization, expression pattern, and functional analysis of
RT the OsIRL gene family encoding intracellular Ras-group-related LRR proteins
RT in rice.";
RL Plant Mol. Biol. 74:617-629(2010).
CC -!- FUNCTION: Leucine-rich repeat protein that likely mediates protein
CC interactions, possibly in the context of signal transduction.
CC {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Widely expressed except in panicles.
CC {ECO:0000269|PubMed:20949308}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype.
CC {ECO:0000269|PubMed:20949308}.
CC -!- SIMILARITY: Belongs to the SHOC2 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABB47746.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; DP000086; AAP54084.1; -; Genomic_DNA.
DR EMBL; DP000086; ABB47746.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP008216; BAF26667.1; -; Genomic_DNA.
DR EMBL; AP014966; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_015614676.1; XM_015759190.1.
DR AlphaFoldDB; Q7XDQ7; -.
DR SMR; Q7XDQ7; -.
DR STRING; 4530.OS10T0456200-01; -.
DR PaxDb; Q7XDQ7; -.
DR PRIDE; Q7XDQ7; -.
DR GeneID; 4348792; -.
DR KEGG; osa:4348792; -.
DR eggNOG; KOG0619; Eukaryota.
DR HOGENOM; CLU_000288_18_15_1; -.
DR InParanoid; Q7XDQ7; -.
DR OrthoDB; 1348484at2759; -.
DR Proteomes; UP000000763; Chromosome 10.
DR Proteomes; UP000059680; Chromosome 10.
DR Genevisible; Q7XDQ7; OS.
DR Gene3D; 3.80.10.10; -; 2.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000626; Ubiquitin-like_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR Pfam; PF13855; LRR_8; 2.
DR Pfam; PF00240; ubiquitin; 1.
DR SMART; SM00369; LRR_TYP; 6.
DR SMART; SM00213; UBQ; 1.
DR SUPFAM; SSF54236; SSF54236; 1.
DR PROSITE; PS51450; LRR; 6.
DR PROSITE; PS50053; UBIQUITIN_2; 1.
PE 2: Evidence at transcript level;
KW Leucine-rich repeat; Reference proteome; Repeat.
FT CHAIN 1..378
FT /note="Plant intracellular Ras-group-related LRR protein 8"
FT /id="PRO_0000423617"
FT DOMAIN 10..86
FT /note="Ubiquitin-like"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00214"
FT REPEAT 129..152
FT /note="LRR 1"
FT REPEAT 153..176
FT /note="LRR 2"
FT REPEAT 178..201
FT /note="LRR 3"
FT REPEAT 202..225
FT /note="LRR 4"
FT REPEAT 226..250
FT /note="LRR 5"
FT REPEAT 252..271
FT /note="LRR 6"
FT REPEAT 272..293
FT /note="LRR 7"
FT REPEAT 294..317
FT /note="LRR 8"
FT REPEAT 319..344
FT /note="LRR 9"
FT REGION 85..120
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 88..120
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 378 AA; 41075 MW; 337E63CB025D912A CRC64;
MESSPPPPPP TITVQVKFGG RTIPVEVPAA ATAADLKRLL QPLTNVLPRG QRLICKGKVL
ADAASLSSMQ VVNGSKVMLM ASQGLHQGDG PITKNSSVPA PSTRRASNVK EAQIQKSDTN
VSKIRPERWK ATGIIALSDS SLKAVPEEVW GCGSSIRVLD VSNNCIEAIP QEIAALRSLQ
KLILTANDIA DGNISWEGLT CVQTLTVLSL SQNRLVTLPS SLGSITHLRE LRIANNRLEN
LPVEIGLLKH LEILIANNNR ITSLPSSIGG CESLNEVDLS SNLLAELPEA FGNLQHLKAL
SVRNNGLTSL PSAFFIKCSQ LITLDLHGTE ITNDVLRQVD GWEEFDERRR KKHQKQLDFR
VGSSVVFDEG ADDDYRRL
