PITH1_ARATH
ID PITH1_ARATH Reviewed; 176 AA.
AC Q9SQZ9; Q93Z56; Q9CAU6;
DT 24-JAN-2006, integrated into UniProtKB/Swiss-Prot.
DT 24-JAN-2006, sequence version 2.
DT 25-MAY-2022, entry version 124.
DE RecName: Full=PITH domain-containing protein At3g04780;
GN OrderedLocusNames=At3g04780; ORFNames=F7O18.27, T9J14.27;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2, CLEAVAGE OF INITIATOR
RP METHIONINE [LARGE SCALE ANALYSIS], AND IDENTIFICATION BY MASS SPECTROMETRY
RP [LARGE SCALE ANALYSIS].
RX PubMed=22223895; DOI=10.1074/mcp.m111.015131;
RA Bienvenut W.V., Sumpton D., Martinez A., Lilla S., Espagne C., Meinnel T.,
RA Giglione C.;
RT "Comparative large-scale characterisation of plant vs. mammal proteins
RT reveals similar and idiosyncratic N-alpha acetylation features.";
RL Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012).
RN [6]
RP STRUCTURE BY NMR OF 2-161.
RX PubMed=15741346; DOI=10.1110/ps.041246805;
RA Song J., Tyler R.C., Wrobel R.L., Frederick R.O., Vojtek F.C., Jeon W.B.,
RA Lee M.S., Markley J.L.;
RT "Solution structure of At3g04780.1-des15, an Arabidopsis thaliana ortholog
RT of the C-terminal domain of human thioredoxin-like protein.";
RL Protein Sci. 14:1059-1063(2005).
CC -!- SIMILARITY: Belongs to the PITHD1 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF04904.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC009465; AAG51403.1; -; Genomic_DNA.
DR EMBL; AC011437; AAF04904.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE74135.1; -; Genomic_DNA.
DR EMBL; AY058116; AAL25533.1; -; mRNA.
DR EMBL; AY093713; AAM10337.1; -; mRNA.
DR EMBL; AY088225; AAM65766.1; -; mRNA.
DR RefSeq; NP_566238.1; NM_111350.3.
DR PDB; 1XOY; NMR; -; A=2-161.
DR PDBsum; 1XOY; -.
DR AlphaFoldDB; Q9SQZ9; -.
DR BMRB; Q9SQZ9; -.
DR SMR; Q9SQZ9; -.
DR STRING; 3702.AT3G04780.1; -.
DR iPTMnet; Q9SQZ9; -.
DR PaxDb; Q9SQZ9; -.
DR PRIDE; Q9SQZ9; -.
DR ProteomicsDB; 236739; -.
DR DNASU; 819638; -.
DR EnsemblPlants; AT3G04780.1; AT3G04780.1; AT3G04780.
DR GeneID; 819638; -.
DR Gramene; AT3G04780.1; AT3G04780.1; AT3G04780.
DR KEGG; ath:AT3G04780; -.
DR Araport; AT3G04780; -.
DR TAIR; locus:2084883; AT3G04780.
DR eggNOG; KOG0908; Eukaryota.
DR HOGENOM; CLU_072377_1_0_1; -.
DR InParanoid; Q9SQZ9; -.
DR OMA; PLAGTNM; -.
DR OrthoDB; 1482186at2759; -.
DR PhylomeDB; Q9SQZ9; -.
DR EvolutionaryTrace; Q9SQZ9; -.
DR PRO; PR:Q9SQZ9; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9SQZ9; baseline and differential.
DR Genevisible; Q9SQZ9; AT.
DR GO; GO:0005829; C:cytosol; HDA:TAIR.
DR DisProt; DP00434; -.
DR Gene3D; 2.60.120.470; -; 1.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR045099; PITH1-like.
DR InterPro; IPR010400; PITH_dom.
DR InterPro; IPR037047; PITH_dom_sf.
DR PANTHER; PTHR12175; PTHR12175; 1.
DR Pfam; PF06201; PITH; 1.
DR SUPFAM; SSF49785; SSF49785; 1.
DR PROSITE; PS51532; PITH; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Acetylation; Reference proteome.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0007744|PubMed:22223895"
FT CHAIN 2..176
FT /note="PITH domain-containing protein At3g04780"
FT /id="PRO_0000220606"
FT DOMAIN 5..176
FT /note="PITH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00864"
FT MOD_RES 2
FT /note="N-acetylserine"
FT /evidence="ECO:0007744|PubMed:22223895"
FT STRAND 14..17
FT /evidence="ECO:0007829|PDB:1XOY"
FT STRAND 26..28
FT /evidence="ECO:0007829|PDB:1XOY"
FT HELIX 37..40
FT /evidence="ECO:0007829|PDB:1XOY"
FT STRAND 58..70
FT /evidence="ECO:0007829|PDB:1XOY"
FT STRAND 72..78
FT /evidence="ECO:0007829|PDB:1XOY"
FT TURN 81..83
FT /evidence="ECO:0007829|PDB:1XOY"
FT STRAND 84..93
FT /evidence="ECO:0007829|PDB:1XOY"
FT HELIX 99..102
FT /evidence="ECO:0007829|PDB:1XOY"
FT STRAND 108..111
FT /evidence="ECO:0007829|PDB:1XOY"
FT HELIX 117..119
FT /evidence="ECO:0007829|PDB:1XOY"
FT TURN 127..129
FT /evidence="ECO:0007829|PDB:1XOY"
FT STRAND 133..143
FT /evidence="ECO:0007829|PDB:1XOY"
FT STRAND 151..159
FT /evidence="ECO:0007829|PDB:1XOY"
SQ SEQUENCE 176 AA; 19670 MW; 20DBA2DF1EC0DD5D CRC64;
MSAESASQIP KGQVDLLDFI DWSGVECLNQ SSSHSLPNAL KQGYREDEGL NLESDADEQL
LIYIPFNQVI KLHSFAIKGP EEEGPKTVKF FSNKEHMCFS NVNDFPPSDT AELTEENLKG
KPVVLKYVKF QNVRSLTIFI EANQSGSEVT KVQKIALYGS TVETTDMKGL KKIEDH
