ID   PITH1_DICDI             Reviewed;         202 AA.
AC   Q54Z24;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=PITH domain-containing protein 1;
GN   ORFNames=DDB_G0277951;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SIMILARITY: Belongs to the PITHD1 family. {ECO:0000305}.
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DR   EMBL; AAFI02000023; EAL68148.1; -; Genomic_DNA.
DR   RefSeq; XP_642028.1; XM_636936.1.
DR   AlphaFoldDB; Q54Z24; -.
DR   SMR; Q54Z24; -.
DR   STRING; 44689.DDB0302532; -.
DR   PaxDb; Q54Z24; -.
DR   EnsemblProtists; EAL68148; EAL68148; DDB_G0277951.
DR   GeneID; 8621239; -.
DR   KEGG; ddi:DDB_G0277951; -.
DR   dictyBase; DDB_G0277951; -.
DR   eggNOG; KOG1730; Eukaryota.
DR   HOGENOM; CLU_072377_2_0_1; -.
DR   InParanoid; Q54Z24; -.
DR   OMA; YHGVTIC; -.
DR   PhylomeDB; Q54Z24; -.
DR   PRO; PR:Q54Z24; -.
DR   Proteomes; UP000002195; Chromosome 3.
DR   Gene3D; 2.60.120.470; -; 1.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR045099; PITH1-like.
DR   InterPro; IPR010400; PITH_dom.
DR   InterPro; IPR037047; PITH_dom_sf.
DR   PANTHER; PTHR12175; PTHR12175; 1.
DR   Pfam; PF06201; PITH; 1.
DR   SUPFAM; SSF49785; SSF49785; 1.
DR   PROSITE; PS51532; PITH; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..202
FT                   /note="PITH domain-containing protein 1"
FT                   /id="PRO_0000339897"
FT   DOMAIN          11..184
FT                   /note="PITH"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00864"
SQ   SEQUENCE   202 AA;  22740 MW;  A16D41371A246DD7 CRC64;
     MAHQCNDSSH SHGVDDGIEY SLNRYLDTGT ITCLNEKVKG SVRHIFKSWE DRHDLKHFVE
     SCDDEELIIN IPFGAVTQIK SIIIIGGDGG SSPNKMKAYI NNSNIDFGNI NSFACTQEWN
     LHEDFEGQIG YSTKPTKFNN INHLTLYFPS NFGSPTTKIY FIALKGVYTS AKREIVNTVY
     ESKPQLQDHK SDIFNGVSHD LS