PITH1_DROME
ID PITH1_DROME Reviewed; 211 AA.
AC Q9VK68; Q7K2H3;
DT 01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 123.
DE RecName: Full=PITH domain-containing protein CG6153;
GN ORFNames=CG6153;
OS Drosophila melanogaster (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7227;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley;
RX PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A.,
RA An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F.,
RA Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F.,
RA Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R.,
RA Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y.,
RA Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T.,
RA Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S.,
RA Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W.,
RA Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M.,
RA Venter J.C.;
RT "The genome sequence of Drosophila melanogaster.";
RL Science 287:2185-2195(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=Berkeley;
RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT review.";
RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Berkeley; TISSUE=Ovary;
RX PubMed=12537569; DOI=10.1186/gb-2002-3-12-research0080;
RA Stapleton M., Carlson J.W., Brokstein P., Yu C., Champe M., George R.A.,
RA Guarin H., Kronmiller B., Pacleb J.M., Park S., Wan K.H., Rubin G.M.,
RA Celniker S.E.;
RT "A Drosophila full-length cDNA resource.";
RL Genome Biol. 3:RESEARCH0080.1-RESEARCH0080.8(2002).
CC -!- SIMILARITY: Belongs to the PITHD1 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAL28536.2; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AE014134; AAF53211.1; -; Genomic_DNA.
DR EMBL; AY060988; AAL28536.2; ALT_INIT; mRNA.
DR RefSeq; NP_001162966.2; NM_001169495.2.
DR RefSeq; NP_609580.1; NM_135736.4.
DR AlphaFoldDB; Q9VK68; -.
DR SMR; Q9VK68; -.
DR STRING; 7227.FBpp0289503; -.
DR PRIDE; Q9VK68; -.
DR DNASU; 34675; -.
DR EnsemblMetazoa; FBtr0080394; FBpp0079975; FBgn0032445.
DR EnsemblMetazoa; FBtr0340541; FBpp0309440; FBgn0032445.
DR GeneID; 34675; -.
DR KEGG; dme:Dmel_CG6153; -.
DR UCSC; CG6153-RA; d. melanogaster.
DR FlyBase; FBgn0032445; CG6153.
DR VEuPathDB; VectorBase:FBgn0032445; -.
DR eggNOG; KOG1730; Eukaryota.
DR GeneTree; ENSGT00490000043398; -.
DR HOGENOM; CLU_072377_2_0_1; -.
DR InParanoid; Q9VK68; -.
DR OMA; YHGVTIC; -.
DR OrthoDB; 1561790at2759; -.
DR PhylomeDB; Q9VK68; -.
DR BioGRID-ORCS; 34675; 0 hits in 1 CRISPR screen.
DR GenomeRNAi; 34675; -.
DR PRO; PR:Q9VK68; -.
DR Proteomes; UP000000803; Chromosome 2L.
DR Bgee; FBgn0032445; Expressed in secondary oocyte and 21 other tissues.
DR ExpressionAtlas; Q9VK68; baseline and differential.
DR Genevisible; Q9VK68; DM.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR Gene3D; 2.60.120.470; -; 1.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR045099; PITH1-like.
DR InterPro; IPR010400; PITH_dom.
DR InterPro; IPR037047; PITH_dom_sf.
DR PANTHER; PTHR12175; PTHR12175; 1.
DR Pfam; PF06201; PITH; 1.
DR SUPFAM; SSF49785; SSF49785; 1.
DR PROSITE; PS51532; PITH; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..211
FT /note="PITH domain-containing protein CG6153"
FT /id="PRO_0000285036"
FT DOMAIN 20..192
FT /note="PITH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00864"
SQ SEQUENCE 211 AA; 23917 MW; D97353629CE68D63 CRC64;
MPHGHSHDHG GCSHEASDVD HALEMGIEYS LYTKIDLDNV ECLNEETDGQ GKSVFKPYEK
RQDLSKYVES DADEELLFNI PFTGNIKLKG IIISGANDDS HPNMVKIFKN RPRMTFDDAR
AKPDQEFQLT RDARGEIEYS PKVVTFSSVH HLSLYFPSNF GEDITRIYYI GLRGEFTEAH
YHGVTICNYE SRANAADHKE KAFDGVGRAI Q
