ID   PIT_MYCBO               Reviewed;         417 AA.
AC   P59950; A0A1R3XW73; X2BFE2;
DT   31-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT   31-OCT-2003, sequence version 1.
DT   25-MAY-2022, entry version 96.
DE   RecName: Full=Probable low-affinity inorganic phosphate transporter;
GN   Name=pit; Synonyms=pitA; OrderedLocusNames=BQ2027_MB0559C;
OS   Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=233413;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA   Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA   Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA   Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA   Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT   "The complete genome sequence of Mycobacterium bovis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA   Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA   Robbe-Austerman S., Gordon S.V.;
RT   "Updated reference genome sequence and annotation of Mycobacterium bovis
RT   AF2122/97.";
RL   Genome Announc. 5:E00157-E00157(2017).
CC   -!- FUNCTION: Low-affinity inorganic phosphate transport. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the inorganic phosphate transporter (PiT) (TC
CC       2.A.20) family. Pit subfamily. {ECO:0000305}.
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DR   EMBL; LT708304; SIT99155.1; -; Genomic_DNA.
DR   RefSeq; NP_854220.1; NC_002945.3.
DR   RefSeq; WP_003402904.1; NC_002945.4.
DR   AlphaFoldDB; P59950; -.
DR   SMR; P59950; -.
DR   TCDB; 2.A.20.1.3; the inorganic phosphate transporter (pit) family.
DR   PATRIC; fig|233413.5.peg.607; -.
DR   OMA; GYDITRT; -.
DR   Proteomes; UP000001419; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005315; F:inorganic phosphate transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006817; P:phosphate ion transport; IEA:UniProtKB-KW.
DR   InterPro; IPR001204; Phos_transporter.
DR   PANTHER; PTHR11101; PTHR11101; 1.
DR   Pfam; PF01384; PHO4; 2.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Phosphate transport; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..417
FT                   /note="Probable low-affinity inorganic phosphate
FT                   transporter"
FT                   /id="PRO_0000080790"
FT   TRANSMEM        5..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        44..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        81..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        108..128
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        135..155
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        218..238
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        301..321
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        327..347
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          379..417
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        388..405
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   417 AA;  42735 MW;  D22C23184E508B5B CRC64;
     MNLQLFLLLI VVVTALAFDF TNGFHDTGNA MATSIASGAL APRVAVALSA VLNLIGAFLS
     TAVAATIAKG LIDANLVTLE LVFAGLVGGI VWNLLTWLLG IPSSSSHALI GGIVGATIAA
     VGLRGVIWSG VVSKVIVPAV VAALLATLVG AVGTWLVYRT TRGVAEKRTE RGFRRGQIGS
     ASLVSLAHGT NDAQKTMGVI FLALMSYGAV STTASVPPLW VIVSCAVAMA AGTYLGGWRI
     IRTLGKGLVE IKPPQGMAAE SSSAAVILLS AHFGYALSTT QVATGSVLGS GVGKPGAEVR
     WGVAGRMVVA WLVTLPLAGL VGAFTYGLVH FIGGYPGAIL GFALLWLTAT AIWLRSRRAP
     IDHTNVNADW EGNLTAGLEA GAQPLADQRP PVPAPPAPTP PPNHRAPQFG VTTRNAP