PIYH2_XYLFT
ID PIYH2_XYLFT Reviewed; 1219 AA.
AC Q87E25;
DT 04-FEB-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 03-AUG-2022, entry version 84.
DE RecName: Full=Type IV pilus biogenesis factor PilY1 homolog PD_0502 {ECO:0000250|UniProtKB:S0HPF7, ECO:0000303|PubMed:25217013};
DE Flags: Precursor;
GN Name=pilY1_2 {ECO:0000312|EMBL:AAO28377.1};
GN OrderedLocusNames=PD_0502 {ECO:0000312|EMBL:AAO28377.1};
OS Xylella fastidiosa (strain Temecula1 / ATCC 700964).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Xylella.
OX NCBI_TaxID=183190 {ECO:0000312|EMBL:AAO28377.1};
RN [1] {ECO:0000312|EMBL:AAO28377.1, ECO:0000312|Proteomes:UP000002516}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Temecula1 / ATCC 700964 {ECO:0000312|Proteomes:UP000002516};
RX PubMed=12533478; DOI=10.1128/jb.185.3.1018-1026.2003;
RA Van Sluys M.A., de Oliveira M.C., Monteiro-Vitorello C.B., Miyaki C.Y.,
RA Furlan L.R., Camargo L.E.A., da Silva A.C.R., Moon D.H., Takita M.A.,
RA Lemos E.G.M., Machado M.A., Ferro M.I.T., da Silva F.R., Goldman M.H.S.,
RA Goldman G.H., Lemos M.V.F., El-Dorry H., Tsai S.M., Carrer H.,
RA Carraro D.M., de Oliveira R.C., Nunes L.R., Siqueira W.J., Coutinho L.L.,
RA Kimura E.T., Ferro E.S., Harakava R., Kuramae E.E., Marino C.L.,
RA Giglioti E., Abreu I.L., Alves L.M.C., do Amaral A.M., Baia G.S.,
RA Blanco S.R., Brito M.S., Cannavan F.S., Celestino A.V., da Cunha A.F.,
RA Fenille R.C., Ferro J.A., Formighieri E.F., Kishi L.T., Leoni S.G.,
RA Oliveira A.R., Rosa V.E. Jr., Sassaki F.T., Sena J.A.D., de Souza A.A.,
RA Truffi D., Tsukumo F., Yanai G.M., Zaros L.G., Civerolo E.L.,
RA Simpson A.J.G., Almeida N.F. Jr., Setubal J.C., Kitajima J.P.;
RT "Comparative analyses of the complete genome sequences of Pierce's disease
RT and citrus variegated chlorosis strains of Xylella fastidiosa.";
RL J. Bacteriol. 185:1018-1026(2003).
RN [2]
RP IDENTIFICATION, AND INDUCTION.
RC STRAIN=Temecula1 / ATCC 700964 {ECO:0000303|PubMed:25217013};
RX PubMed=25217013; DOI=10.1128/aem.02153-14;
RA Cruz L.F., Parker J.K., Cobine P.A., De La Fuente L.;
RT "Calcium-enhanced twitching motility in Xylella fastidiosa is linked to a
RT single PilY1 homolog.";
RL Appl. Environ. Microbiol. 80:7176-7185(2014).
CC -!- FUNCTION: One of the three PilY1 homologs of X.fastidiosa, which are
CC involved in bacterial twitching motility as component of the
CC filamentous type IV pili (T4P). {ECO:0000305|PubMed:25217013}.
CC -!- SUBCELLULAR LOCATION: Fimbrium {ECO:0000250|UniProtKB:Q87B49}.
CC -!- INDUCTION: Expression is not affected by calcium.
CC {ECO:0000269|PubMed:25217013}.
CC -!- SIMILARITY: Belongs to the PilY1 family. {ECO:0000305}.
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DR EMBL; AE009442; AAO28377.1; -; Genomic_DNA.
DR AlphaFoldDB; Q87E25; -.
DR SMR; Q87E25; -.
DR EnsemblBacteria; AAO28377; AAO28377; PD_0502.
DR KEGG; xft:PD_0502; -.
DR HOGENOM; CLU_001890_0_1_6; -.
DR OMA; AYWAHTY; -.
DR Proteomes; UP000002516; Chromosome.
DR GO; GO:0009289; C:pilus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR InterPro; IPR008707; PilC_beta_prop_dom.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR Pfam; PF05567; Neisseria_PilC; 1.
DR SUPFAM; SSF50998; SSF50998; 1.
PE 2: Evidence at transcript level;
KW Calcium; Fimbrium; Fimbrium biogenesis; Metal-binding; Signal.
FT SIGNAL 1..35
FT /evidence="ECO:0000255"
FT CHAIN 36..1219
FT /note="Type IV pilus biogenesis factor PilY1 homolog
FT PD_0502"
FT /evidence="ECO:0000255"
FT /id="PRO_0000431919"
FT REGION 212..234
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 212..230
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 958
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /evidence="ECO:0000250|UniProtKB:S0HPF7"
FT BINDING 960
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /evidence="ECO:0000250|UniProtKB:S0HPF7"
FT BINDING 962
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /evidence="ECO:0000250|UniProtKB:S0HPF7"
FT BINDING 964
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /evidence="ECO:0000250|UniProtKB:S0HPF7"
SQ SEQUENCE 1219 AA; 132995 MW; 1324CA38DF193772 CRC64;
MVGMSRIILN NLFFFRCVVA VFSAHSLVIS GAVHAGVQIS QSPLHGGGDV PGNLAIVASI
EFPTVISVAN LADTYTPGVR YVGYFDSNKC YKYHYSSREL DRYFYPVASP RPQANYGCNT
TGGVWAGNFL NWAATQTIDP FRSALTGGYR VRDTANETIL EKAVMDRAYP GNFPRRTIEG
LALTTSVPAQ WLRFRMRIDG LGNRMRFTQF PGLSTDPLNT EGQPYDPSRH PLNSNDRGVY
EVSVRVKVCD ASVGLESNCV AYPSGFYKPE GLVQEYSKRV RYSVFSYKND DYYLDDGGVL
RARQKFVGPK TYYPEQGEKT NPHAEWHPRT GVLYDNPNPE DAKATTHRVG RTIGNSGVIN
YLNKFSQMET GKNTKGFDPV SELYYTAYRY FKRLGNVPEY SVLTGSVNEK YQQADAFPVI
TDWDDPIRYA CQSNVVLGIG DTHTNFDKNL PGNTNTTGEP VKPQAVRNDR SIDVVKRMAQ
IFQMEGMRQQ DAMTSALAPS FNFLVPGAGN NSAYIAALAY DAHTKDMRPD LEGDQLLTTH
WVDVVEGGDY KIPISTNQYW LAAKYGGFQV PAGYDPDKTV NPLSEATWWT NGEYVNGDTK
AKRADNFYIA ADAEKMVASL KHAFSRIVAE IKGAGTGLSS NSARLETGAV TYQAQFFSGT
WRGDLIAYHV DKVTGALTPF WNANFPAWEQ RVIKFANATT LQDFTKKNLG QTALASASAQ
QINYLRGDRS QEGNVPGKLR IRSGIMGDIV NSQPLYVGAP NGRLYTTANF TGASAYAAFA
AQQANRVPVV YVGANDGMLH AFDANTGKEI FAFVPRAAMP KLLEYTDQNY GHQYYVDGEL
TAADIYDTKL GWRSVLVGTL GRGGKGLFAL DVTDPSNIRL LWDKTSADIG GLGNTLSKPM
IAQTSDGTWS VLLGNGPNST ADNAQLIVMN LLTGHAAQVP VSKTSNNGLS GVFPWSSQSN
GITDRVYAGD LLGTLWRFTF SDNAWKVAPL FTATYQGKAQ PISATPLGAI ERSTGRMWIF
FGTGRALSSH DMDNKEVQSW YGLIDQGTTI PGRTRLSQVQ IVDEGVVNGY AVRTVSDPKN
IGTDGWYMDL ISPKSGKQGE RMIVSNMFRG AALIGTTRIP DNSDICKLSG SGFVMAINPF
TGGRLGQWFF DLNTGGGSGG ALNGNPVSGV GVSSAPNSPV FTGNIMQIGA DDGTVTSLKT
PSSGGLNINR VSWREILRP
