ID   PK1_DELRA               Reviewed;          15 AA.
AC   B3EWL1; B3EWL2;
DT   03-OCT-2012, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2012, sequence version 1.
DT   02-JUN-2021, entry version 10.
DE   RecName: Full=CAPA-Pyrokinin {ECO:0000303|PubMed:22848525};
DE            Short=CAPA-PK {ECO:0000303|PubMed:22848525};
DE   Contains:
DE     RecName: Full=CAPA-Pyrokinin(2-15) {ECO:0000303|PubMed:22848525};
DE              Short=CAPA-PK(2-15) {ECO:0000303|PubMed:22848525};
OS   Delia radicum (Cabbage root fly) (Anthomyia brassicae).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC   Anthomyiidae; Anthomyiinae; Delia.
OX   NCBI_TaxID=30064;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE, MASS
RP   SPECTROMETRY, AND AMIDATION AT LEU-15.
RC   TISSUE=CNS {ECO:0000269|PubMed:22848525};
RX   PubMed=22848525; DOI=10.1371/journal.pone.0041543;
RA   Zoephel J., Reiher W., Rexer K.-H., Kahnt J., Wegener C.;
RT   "Peptidomics of the agriculturally damaging larval stage of the cabbage
RT   root fly Delia radicum (Diptera: Anthomyiidae).";
RL   PLoS ONE 7:E41543-E41543(2012).
CC   -!- FUNCTION: Mediates visceral muscle contractile activity (myotropic
CC       activity). {ECO:0000250|UniProtKB:P41489}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P41489}.
CC   -!- TISSUE SPECIFICITY: Both CAPA-pyrokinin and CAPA-pyrokinin(2-15) are
CC       expressed in CNS, ring gland and abdominal perisympathetic organs
CC       (aPSO) but not in midgut or thoracic perisympathetic organs (tPSO) (at
CC       protein level). {ECO:0000269|PubMed:22848525}.
CC   -!- DEVELOPMENTAL STAGE: Detected in larvae. {ECO:0000269|PubMed:22848525}.
CC   -!- MASS SPECTROMETRY: [CAPA-Pyrokinin]: Mass=1515.81; Method=MALDI;
CC       Evidence={ECO:0000269|PubMed:22848525};
CC   -!- MASS SPECTROMETRY: [CAPA-Pyrokinin(2-15)]: Mass=1444.78; Method=MALDI;
CC       Evidence={ECO:0000269|PubMed:22848525};
CC   -!- SIMILARITY: Belongs to the pyrokinin family. {ECO:0000255}.
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DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005184; F:neuropeptide hormone activity; IEA:InterPro.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   InterPro; IPR001484; Pyrokinin_CS.
DR   PROSITE; PS00539; PYROKININ; 1.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Neuropeptide; Secreted.
FT   PEPTIDE         1..15
FT                   /note="CAPA-Pyrokinin"
FT                   /evidence="ECO:0000269|PubMed:22848525"
FT                   /id="PRO_0000419730"
FT   PEPTIDE         2..15
FT                   /note="CAPA-Pyrokinin(2-15)"
FT                   /evidence="ECO:0000269|PubMed:22848525"
FT                   /id="PRO_0000419731"
FT   MOD_RES         15
FT                   /note="Leucine amide"
FT                   /evidence="ECO:0000269|PubMed:22848525"
FT   UNSURE          15
FT                   /note="L or I"
FT                   /evidence="ECO:0000269|PubMed:22848525"
SQ   SEQUENCE   15 AA;  1517 MW;  3C70432BE394A9CD CRC64;
     AGPSATTGVW FGPRL