ID   PK81E_PSEFD             Reviewed;         442 AA.
AC   M3APK0;
DT   07-OCT-2020, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2013, sequence version 1.
DT   25-MAY-2022, entry version 34.
DE   RecName: Full=Transcription factor MYCFIDRAFT_198930 {ECO:0000303|PubMed:30735556};
DE   AltName: Full=PKS8-1 gene cluster protein MYCFIDRAFT_198930 {ECO:0000303|PubMed:30735556};
GN   ORFNames=MYCFIDRAFT_198930;
OS   Pseudocercospora fijiensis (strain CIRAD86) (Black leaf streak disease
OS   fungus) (Mycosphaerella fijiensis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Pseudocercospora.
OX   NCBI_TaxID=383855;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CIRAD86;
RX   PubMed=23236275; DOI=10.1371/journal.ppat.1003037;
RA   Ohm R.A., Feau N., Henrissat B., Schoch C.L., Horwitz B.A., Barry K.W.,
RA   Condon B.J., Copeland A.C., Dhillon B., Glaser F., Hesse C.N., Kosti I.,
RA   LaButti K., Lindquist E.A., Lucas S., Salamov A.A., Bradshaw R.E.,
RA   Ciuffetti L., Hamelin R.C., Kema G.H.J., Lawrence C., Scott J.A.,
RA   Spatafora J.W., Turgeon B.G., de Wit P.J.G.M., Zhong S., Goodwin S.B.,
RA   Grigoriev I.V.;
RT   "Diverse lifestyles and strategies of plant pathogenesis encoded in the
RT   genomes of eighteen Dothideomycetes fungi.";
RL   PLoS Pathog. 8:E1003037-E1003037(2012).
RN   [2]
RP   IDENTIFICATION, AND FUNCTION.
RX   PubMed=27388157; DOI=10.1371/journal.pone.0158471;
RA   Noar R.D., Daub M.E.;
RT   "Bioinformatics prediction of polyketide synthase gene clusters from
RT   Mycosphaerella fijiensis.";
RL   PLoS ONE 11:e0158471-e0158471(2016).
RN   [3]
RP   FUNCTION.
RX   PubMed=30735556; DOI=10.1371/journal.pone.0212229;
RA   Noar R.D., Thomas E., Daub M.E.;
RT   "A novel polyketide synthase gene cluster in the plant pathogenic fungus
RT   Pseudocercospora fijiensis.";
RL   PLoS ONE 14:e0212229-e0212229(2019).
CC   -!- FUNCTION: Transcription factor that positively regulates the expression
CC       of the gene cluster that mediates the biosynthesis of an emodin
CC       derivative that may be involved in black Sigatoka disease of banana.
CC       {ECO:0000269|PubMed:27388157, ECO:0000269|PubMed:30735556}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00227}.
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DR   EMBL; KB446562; EME79053.1; -; Genomic_DNA.
DR   RefSeq; XP_007929880.1; XM_007931689.1.
DR   AlphaFoldDB; M3APK0; -.
DR   SMR; M3APK0; -.
DR   STRING; 383855.M3APK0; -.
DR   EnsemblFungi; EME79053; EME79053; MYCFIDRAFT_198930.
DR   GeneID; 19335767; -.
DR   KEGG; pfj:MYCFIDRAFT_198930; -.
DR   eggNOG; ENOG502SUW5; Eukaryota.
DR   HOGENOM; CLU_031656_1_0_1; -.
DR   OrthoDB; 1396569at2759; -.
DR   Proteomes; UP000016932; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0045122; P:aflatoxin biosynthetic process; IEA:InterPro.
DR   CDD; cd00067; GAL4; 1.
DR   Gene3D; 4.10.240.10; -; 1.
DR   InterPro; IPR013700; AflR.
DR   InterPro; IPR001138; Zn2-C6_fun-type_DNA-bd.
DR   InterPro; IPR036864; Zn2-C6_fun-type_DNA-bd_sf.
DR   Pfam; PF08493; AflR; 1.
DR   Pfam; PF00172; Zn_clus; 1.
DR   SMART; SM00066; GAL4; 1.
DR   SUPFAM; SSF57701; SSF57701; 1.
DR   PROSITE; PS00463; ZN2_CY6_FUNGAL_1; 1.
DR   PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Metal-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..442
FT                   /note="Transcription factor MYCFIDRAFT_198930"
FT                   /id="PRO_0000451122"
FT   DNA_BIND        36..63
FT                   /note="Zn(2)-C6 fungal-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00227"
FT   REGION          1..34
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          74..107
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        18..34
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   442 AA;  48209 MW;  8B3DFEAD58C09CDB CRC64;
     MSTTPMAAPP GADLKPVTSS RGRSSTSDEQ KLRSSCESCA QSKLKCSGDK PACARCAKRG
     LACKYVIAKR GGRKPKGYTS TNDNNPSKRR EDSHSPAASQ WSSTGHLEQS YPYCDPTISG
     SASPALIAMS DFYNPMDQNL PDAPTSHSDI SMDFDFNDCF SLGFPSSNEL SDFCNVGSTD
     MFSPSLDSSS SSSTGPERQL LCDGFSLTDD AMSDLFPLSP PEPQQQISCT PTDKNPHSYQ
     EACLNGSCSC LVEALSLMKQ LVSSPARNGA ASPPNIQTII DRNEATIESV RRMLECSCSQ
     DDGYLLSVMS LIIFRVLGWY ATVARQTACD VDSQPSRSPQ SSISSAGSGY CLEGADSARM
     AAQLVLSEIH HVRRIVHQLS LKLKAQGEKE RSRPETRMEG LEAMDNEMTL PLSATMYDQL
     DVDLKKRLRA LSWEMIDRLR RY