ID   PKG6_BPPRD              Reviewed;         166 AA.
AC   P27379; Q3T4N7;
DT   01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1992, sequence version 1.
DT   29-SEP-2021, entry version 65.
DE   RecName: Full=Packaging efficiency factor P6;
GN   Name=VI;
OS   Enterobacteria phage PRD1 (Bacteriophage PRD1).
OC   Viruses; Varidnaviria; Bamfordvirae; Preplasmiviricota; Tectiliviricetes;
OC   Kalamavirales; Tectiviridae; Alphatectivirus.
OX   NCBI_TaxID=10658;
OH   NCBI_TaxID=471; Acinetobacter calcoaceticus.
OH   NCBI_TaxID=562; Escherichia coli.
OH   NCBI_TaxID=584; Proteus mirabilis.
OH   NCBI_TaxID=287; Pseudomonas aeruginosa.
OH   NCBI_TaxID=294; Pseudomonas fluorescens.
OH   NCBI_TaxID=303; Pseudomonas putida (Arthrobacter siderocapsulatus).
OH   NCBI_TaxID=90371; Salmonella typhimurium.
OH   NCBI_TaxID=666; Vibrio cholerae.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF 1-6.
RX   PubMed=1853567; DOI=10.1016/0042-6822(91)90995-n;
RA   Bamford J.K.H., Haenninen A.-L., Pakula T.M., Ojala P.M., Kalkkinen N.,
RA   Frilander M., Bamford D.H.;
RT   "Genome organization of membrane-containing bacteriophage PRD1.";
RL   Virology 183:658-676(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=15946683; DOI=10.1016/j.jmb.2005.04.059;
RA   Saren A.M., Ravantti J.J., Benson S.D., Burnett R.M., Paulin L.,
RA   Bamford D.H., Bamford J.K.H.;
RT   "A snapshot of viral evolution from genome analysis of the tectiviridae
RT   family.";
RL   J. Mol. Biol. 350:427-440(2005).
RN   [3]
RP   IDENTIFICATION IN THE PORTAL COMPLEX, AND SUBCELLULAR LOCATION.
RX   PubMed=12743288; DOI=10.1128/jvi.77.11.6314-6321.2003;
RA   Stromsten N.J., Bamford D.H., Bamford J.K.H.;
RT   "The unique vertex of bacterial virus PRD1 is connected to the viral
RT   internal membrane.";
RL   J. Virol. 77:6314-6321(2003).
RN   [4]
RP   FUNCTION, SUBUNIT, AND IDENTIFICATION IN THE PORTAL COMPLEX.
RX   PubMed=25514469; DOI=10.1371/journal.pbio.1002024;
RA   Hong C., Oksanen H.M., Liu X., Jakana J., Bamford D.H., Chiu W.;
RT   "A structural model of the genome packaging process in a membrane-
RT   containing double stranded DNA virus.";
RL   PLoS Biol. 12:E1002024-E1002024(2014).
CC   -!- FUNCTION: Together with the packaging ATPase P9, forms the external
CC       part of the portal vertex that is embeded in the capsid and which plays
CC       critical roles in genome packaging and genome ejection. Both proteins
CC       multimerize as a single ring-shaped heterdodecamer arranged around a
CC       central channel. {ECO:0000269|PubMed:25514469}.
CC   -!- SUBUNIT: Heterodimer of P6 and P9; further multimerizes as hexamers of
CC       heterodimers. Part of the dodecameric portal complex that is composed
CC       of the packaging efficiency factor P6, the DNA packaging ATPase P9, and
CC       the internal heterododecamer P20/P22 which spans the virion inner
CC       membrane. {ECO:0000269|PubMed:12743288, ECO:0000269|PubMed:25514469}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}. Note=Localizes at the
CC       unique vertex of the capsid, which extends to the internal membrane via
CC       two small integral membrane proteins, P20 and P22. Packaging efficiency
CC       factor P6 attaches to the virion via these proteins and is, in turn,
CC       necessary for the attachment of DNA packaging protein P9 to the capsid.
CC       {ECO:0000269|PubMed:12743288}.
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DR   EMBL; AY848689; AAX45924.1; -; Genomic_DNA.
DR   PIR; H40477; WMBPP6.
DR   RefSeq; NP_040688.1; NC_001421.2.
DR   SMR; P27379; -.
DR   Proteomes; UP000002143; Genome.
DR   GO; GO:0019073; P:viral DNA genome packaging; IMP:CACAO.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Reference proteome; Viral genome packaging;
KW   Viral release from host cell; Virion.
FT   CHAIN           1..166
FT                   /note="Packaging efficiency factor P6"
FT                   /id="PRO_0000165350"
FT   REGION          134..166
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   166 AA;  17573 MW;  DC6D2DBE282195DA CRC64;
     MDTEEIKEEM QEAAEAAIEN AVETAELETA AIKAEGAAAA AEQSAEQAAV MAATLAASVE
     ANAAQQIAEH SEQVQTQEEK ISWLENQVMA MASNLQMMQE AVTALTVSQS LTPEPSPVPA
     VEVEAMPEAV TVEILPESAG DQQEAEPVPS VGDQQETAPR KRFRAI