PKHA9_HUMAN
ID PKHA9_HUMAN Reviewed; 391 AA.
AC O95397;
DT 02-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 25-MAY-2022, entry version 117.
DE RecName: Full=Putative protein PLEKHA9;
DE AltName: Full=Pleckstrin homology domain-containing family A member 8 pseudogene 1;
GN Name=PLEKHA8P1; Synonyms=PLEKHA9; ORFNames=HAW1053;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Aorta;
RA Wei Y.J., Ding J.F., Xu Y.Y., Liu Y.Q., Hui R.T., Sheng H., Zhao X.W.,
RA Jiang Y.X., Meng X.M., Liu D.Q., Zhao Y., Cao H.Q., Liu S.;
RT "Prediction of the coding sequences of unidentified human genes. I. The
RT complete sequence of HAW1053 cDNA clone from human adult aorta cDNA
RT library.";
RL Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16541075; DOI=10.1038/nature04569;
RA Scherer S.E., Muzny D.M., Buhay C.J., Chen R., Cree A., Ding Y.,
RA Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C.,
RA Hernandez J., Hodgson A.V., Hume J., Jackson A., Khan Z.M., Kovar-Smith C.,
RA Lewis L.R., Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R.,
RA Montgomery K.T., Morgan M.B., Nazareth L.V., Scott G., Sodergren E.,
RA Song X.-Z., Steffen D., Lovering R.C., Wheeler D.A., Worley K.C., Yuan Y.,
RA Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G.,
RA Chen Z., Clerc-Blankenburg K.P., Davis C., Delgado O., Dinh H.H.,
RA Draper H., Gonzalez-Garay M.L., Havlak P., Jackson L.R., Jacob L.S.,
RA Kelly S.H., Li L., Li Z., Liu J., Liu W., Lu J., Maheshwari M.,
RA Nguyen B.-V., Okwuonu G.O., Pasternak S., Perez L.M., Plopper F.J.H.,
RA Santibanez J., Shen H., Tabor P.E., Verduzco D., Waldron L., Wang Q.,
RA Williams G.A., Zhang J., Zhou J., Allen C.C., Amin A.G., Anyalebechi V.,
RA Bailey M., Barbaria J.A., Bimage K.E., Bryant N.P., Burch P.E.,
RA Burkett C.E., Burrell K.L., Calderon E., Cardenas V., Carter K., Casias K.,
RA Cavazos I., Cavazos S.R., Ceasar H., Chacko J., Chan S.N., Chavez D.,
RA Christopoulos C., Chu J., Cockrell R., Cox C.D., Dang M., Dathorne S.R.,
RA David R., Davis C.M., Davy-Carroll L., Deshazo D.R., Donlin J.E.,
RA D'Souza L., Eaves K.A., Egan A., Emery-Cohen A.J., Escotto M., Flagg N.,
RA Forbes L.D., Gabisi A.M., Garza M., Hamilton C., Henderson N.,
RA Hernandez O., Hines S., Hogues M.E., Huang M., Idlebird D.G., Johnson R.,
RA Jolivet A., Jones S., Kagan R., King L.M., Leal B., Lebow H., Lee S.,
RA LeVan J.M., Lewis L.C., London P., Lorensuhewa L.M., Loulseged H.,
RA Lovett D.A., Lucier A., Lucier R.L., Ma J., Madu R.C., Mapua P.,
RA Martindale A.D., Martinez E., Massey E., Mawhiney S., Meador M.G.,
RA Mendez S., Mercado C., Mercado I.C., Merritt C.E., Miner Z.L., Minja E.,
RA Mitchell T., Mohabbat F., Mohabbat K., Montgomery B., Moore N., Morris S.,
RA Munidasa M., Ngo R.N., Nguyen N.B., Nickerson E., Nwaokelemeh O.O.,
RA Nwokenkwo S., Obregon M., Oguh M., Oragunye N., Oviedo R.J., Parish B.J.,
RA Parker D.N., Parrish J., Parks K.L., Paul H.A., Payton B.A., Perez A.,
RA Perrin W., Pickens A., Primus E.L., Pu L.-L., Puazo M., Quiles M.M.,
RA Quiroz J.B., Rabata D., Reeves K., Ruiz S.J., Shao H., Sisson I.,
RA Sonaike T., Sorelle R.P., Sutton A.E., Svatek A.F., Svetz L.A.,
RA Tamerisa K.S., Taylor T.R., Teague B., Thomas N., Thorn R.D., Trejos Z.Y.,
RA Trevino B.K., Ukegbu O.N., Urban J.B., Vasquez L.I., Vera V.A.,
RA Villasana D.M., Wang L., Ward-Moore S., Warren J.T., Wei X., White F.,
RA Williamson A.L., Wleczyk R., Wooden H.S., Wooden S.H., Yen J., Yoon L.,
RA Yoon V., Zorrilla S.E., Nelson D., Kucherlapati R., Weinstock G.,
RA Gibbs R.A.;
RT "The finished DNA sequence of human chromosome 12.";
RL Nature 440:346-351(2006).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Lung;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
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DR EMBL; AF103731; AAC97956.1; -; mRNA.
DR EMBL; AC009248; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC063575; AAH63575.1; -; mRNA.
DR AlphaFoldDB; O95397; -.
DR SMR; O95397; -.
DR IntAct; O95397; 1.
DR iPTMnet; O95397; -.
DR PhosphoSitePlus; O95397; -.
DR BioMuta; HGNC:30222; -.
DR jPOST; O95397; -.
DR MassIVE; O95397; -.
DR MaxQB; O95397; -.
DR PeptideAtlas; O95397; -.
DR PRIDE; O95397; -.
DR ProteomicsDB; 50848; -.
DR GeneCards; PLEKHA8P1; -.
DR HGNC; HGNC:30222; PLEKHA8P1.
DR neXtProt; NX_O95397; -.
DR PharmGKB; PA134868961; -.
DR InParanoid; O95397; -.
DR PhylomeDB; O95397; -.
DR PathwayCommons; O95397; -.
DR ChiTaRS; PLEKHA8P1; human.
DR Pharos; O95397; Tdark.
DR PRO; PR:O95397; -.
DR Proteomes; UP000005640; Unplaced.
DR RNAct; O95397; protein.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:1902387; F:ceramide 1-phosphate binding; IBA:GO_Central.
DR GO; GO:1902388; F:ceramide 1-phosphate transfer activity; IBA:GO_Central.
DR GO; GO:0035627; P:ceramide transport; IBA:GO_Central.
DR GO; GO:0035621; P:ER to Golgi ceramide transport; IBA:GO_Central.
DR GO; GO:0120009; P:intermembrane lipid transfer; IBA:GO_Central.
DR Gene3D; 1.10.3520.10; -; 1.
DR InterPro; IPR036497; GLTP_sf.
DR InterPro; IPR014830; Glycolipid_transfer_prot_dom.
DR Pfam; PF08718; GLTP; 1.
DR SUPFAM; SSF110004; SSF110004; 1.
PE 5: Uncertain;
KW Reference proteome.
FT CHAIN 1..391
FT /note="Putative protein PLEKHA9"
FT /id="PRO_0000306868"
SQ SEQUENCE 391 AA; 43539 MW; 50E4E200C51D8435 CRC64;
MSELRLCCDL LVQQVDKTKE VTTTGVSNSE EGIDVGTLLK STCNTFLKTL EECMQIANAA
FTSELLYHTP PGSPQLAMLK SSKMKHPIIP IHNSLERQTE LSTCENGSLN MEINGEEEIL
MKNKNSLYLK SAEIDCSISS EENTDDNITV QGEIMKEDRM ENLKNHDNNL SQSGSDSSCS
PECLWEEGKE VIPTFFSTMN TSFSDIELLE DSGIPTEAFL ASCCAVVPVL DKLGPTVFAP
VKMDLVENIK KVNQKYITNK EEFTTLQKIV LHEVEADVAQ VRNSATEALL WLKRGLKFLK
GFLTEVKNGE KDIQTALNNA YGKTLRQHHG WVVRGVFALA LRATPSYEDF VAALTVKEGD
HRKEAFSIGM QRDLSLYLPA MKKQMAILDA L
