ID   PKN3_MYXXA              Reviewed;         547 AA.
AC   Q9XBQ0;
DT   04-APR-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Serine/threonine-protein kinase pkn3;
DE            EC=2.7.11.1;
GN   Name=pkn3;
OS   Myxococcus xanthus.
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Myxococcales;
OC   Cystobacterineae; Myxococcaceae; Myxococcus.
OX   NCBI_TaxID=34;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=DZF1;
RA   Inouye S., Jain R., Ueki T., Nariya H., Xu C., Hsu M., Munoz-Dorado J.,
RA   Farez-Vidal E., Inouye M.;
RT   "Sequence analysis of 13 eukaryotic-like protein Ser/Thr kinases of
RT   Myxococcus xanthus, a developmental bacterium and significance of their
RT   coexistence with protein His kinases.";
RL   Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC         [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC         COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC         threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC         Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC         EC=2.7.11.1;
CC   -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC       kinase family. {ECO:0000255|PROSITE-ProRule:PRU00159}.
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DR   EMBL; AF159689; AAD42851.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q9XBQ0; -.
DR   SMR; Q9XBQ0; -.
DR   PRIDE; Q9XBQ0; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0106310; F:protein serine kinase activity; IEA:RHEA.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006468; P:protein phosphorylation; IEA:InterPro.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR017441; Protein_kinase_ATP_BS.
DR   InterPro; IPR008271; Ser/Thr_kinase_AS.
DR   Pfam; PF00069; Pkinase; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF56112; SSF56112; 1.
DR   PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Kinase; Nucleotide-binding; Serine/threonine-protein kinase;
KW   Transferase.
FT   CHAIN           1..547
FT                   /note="Serine/threonine-protein kinase pkn3"
FT                   /id="PRO_0000171229"
FT   DOMAIN          18..288
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT   REGION          290..327
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   ACT_SITE        142
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00159,
FT                   ECO:0000255|PROSITE-ProRule:PRU10027"
FT   BINDING         24..32
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT   BINDING         47
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
SQ   SEQUENCE   547 AA;  59430 MW;  39452DBF3B228019 CRC64;
     MRTPDTDEYV GKTIAYKYRV EALIGEGGMG KVFRARQLSL DKVVVLKVLR HTLLSDERTV
     ARFQREAKAA SRLNHPNSIS VLDFGQAEDG ALFIAMEYVA GQDLHQILSR EWPLNEGRVV
     RIVSQVLSAL SDAHGAGVIH RDLKPENIMV EPRRNEPDFV KVLDFGIAKI TDSTDDGPAL
     TRAGFVCGTP EYMSPEQARG SQLDHRSDLY AVGVILYQLM TGLLPFESDS AVGFATKHLT
     EEPPPPTRRR PDARISPAME RLILRALSKN PADRPASAEA FKAELQAVDK ERRRMDSAPR
     RSANSSAVLA PLPRKSAASP QSDVRDATLP GWGNEVTMEA TVRALPGVLE PLPANADAMA
     ATRETTDSLV HTQPGAGGSS GVAFFFKSLT ILLVVAALGF FAYYFFMGAG SGGAQDLPYA
     LPTNAPVPAG ANNSAVGASP DVPLYDRAIV SGARNVERAL DVAREGDKAL QRADVGLAAT
     KYREAFSRSG DPELALKLGE VYWHRQNPDK EEARGWWNRH LREQPASKAR ALIEQRLNGA
     VAQPTSP