ID   PKR1_SCHPO              Reviewed;         132 AA.
AC   Q9P7Y3;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=V-type ATPase assembly factor pkr1;
GN   Name=pkr1; ORFNames=SPBP23A10.02;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- FUNCTION: Functions together with the other V-type ATPase assembly
CC       factors in the endoplasmic reticulum to efficiently assemble the V-type
CC       ATPase membrane sector V(0). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein
CC       {ECO:0000269|PubMed:16823372}.
CC   -!- SIMILARITY: Belongs to the PKR1 family. {ECO:0000305}.
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DR   EMBL; CU329671; CAB66430.1; -; Genomic_DNA.
DR   PIR; T50389; T50389.
DR   RefSeq; NP_595814.1; NM_001021718.2.
DR   AlphaFoldDB; Q9P7Y3; -.
DR   STRING; 4896.SPBP23A10.02.1; -.
DR   iPTMnet; Q9P7Y3; -.
DR   MaxQB; Q9P7Y3; -.
DR   PaxDb; Q9P7Y3; -.
DR   EnsemblFungi; SPBP23A10.02.1; SPBP23A10.02.1:pep; SPBP23A10.02.
DR   GeneID; 2541277; -.
DR   KEGG; spo:SPBP23A10.02; -.
DR   PomBase; SPBP23A10.02; pkr1.
DR   VEuPathDB; FungiDB:SPBP23A10.02; -.
DR   eggNOG; ENOG502S6V3; Eukaryota.
DR   HOGENOM; CLU_068499_1_1_1; -.
DR   InParanoid; Q9P7Y3; -.
DR   OMA; LWESIFV; -.
DR   PhylomeDB; Q9P7Y3; -.
DR   PRO; PR:Q9P7Y3; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005783; C:endoplasmic reticulum; HDA:PomBase.
DR   GO; GO:0030176; C:integral component of endoplasmic reticulum membrane; ISO:PomBase.
DR   GO; GO:0070072; P:vacuolar proton-transporting V-type ATPase complex assembly; ISO:PomBase.
DR   InterPro; IPR013945; Pkr1.
DR   PANTHER; PTHR28251; PTHR28251; 1.
DR   Pfam; PF08636; Pkr1; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..132
FT                   /note="V-type ATPase assembly factor pkr1"
FT                   /id="PRO_0000374007"
FT   TOPO_DOM        1..19
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        20..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        41..47
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        48..68
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        69..132
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250"
FT   REGION          80..132
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        80..100
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        108..132
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   132 AA;  14613 MW;  C85262EF292B7012 CRC64;
     MSYWVELWES IFTPGVTPVL AKSAHVACGA LVAVFLGLYI GTKSIHCLIL FFLAICLWLS
     LTWFLVELAH ARVNNDLQMS SQSANKNDDN SNNQNPSNNK EMSDKESDSA TTTQTFSVPE
     ELLRARTTAN NS