PKSF3_CANSA
ID PKSF3_CANSA Reviewed; 385 AA.
AC F1LKH5;
DT 06-FEB-2013, integrated into UniProtKB/Swiss-Prot.
DT 03-MAY-2011, sequence version 1.
DT 25-MAY-2022, entry version 26.
DE RecName: Full=Polyketide synthase 3;
DE EC=2.3.1.-;
GN Name=PKSF3;
OS Cannabis sativa (Hemp) (Marijuana).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Rosales; Cannabaceae; Cannabis.
OX NCBI_TaxID=3483;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], 3D-STRUCTURE MODELING, AND TISSUE SPECIFICITY.
RC STRAIN=cv. Kompolti;
RX PubMed=21637580; DOI=10.1590/s1415-47572010005000088;
RA Flores-Sanchez I.J., Linthorst H.J., Verpoorte R.;
RT "In silicio expression analysis of PKS genes isolated from Cannabis sativa
RT L.";
RL Genet. Mol. Biol. 33:703-713(2010).
CC -!- FUNCTION: Polyketide synthase responsible for the biosynthesis of
CC secondary metabolites. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in male and female flowers, and
CC seedlings. {ECO:0000269|PubMed:21637580}.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC synthases family. {ECO:0000305}.
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DR EMBL; EU551162; ACD76852.1; -; mRNA.
DR AlphaFoldDB; F1LKH5; -.
DR SMR; F1LKH5; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR InterPro; IPR018088; Chalcone/stilbene_synthase_AS.
DR InterPro; IPR011141; Polyketide_synthase_type-III.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11877; PTHR11877; 1.
DR Pfam; PF02797; Chal_sti_synt_C; 1.
DR Pfam; PF00195; Chal_sti_synt_N; 1.
DR PIRSF; PIRSF000451; PKS_III; 1.
DR SUPFAM; SSF53901; SSF53901; 2.
DR PROSITE; PS00441; CHALCONE_SYNTH; 1.
PE 2: Evidence at transcript level;
KW Acyltransferase; Cytoplasm; Transferase.
FT CHAIN 1..385
FT /note="Polyketide synthase 3"
FT /id="PRO_0000421150"
FT ACT_SITE 157
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU10023"
SQ SEQUENCE 385 AA; 42571 MW; CD5399D68227C633 CRC64;
MNHLRAEGPA SVLAIGTANP ENILIQDEFP DYYFRVTKSE HMTQLKEKFR KICDKSMIRK
RNCFLNEEHL KQNPRLVEHE MQTLDARQDM LVVEVPKLGK DACAKAIKEW GQPKSKITHL
IFTSASTTDM PGADYHCAKL LGLSPSVKRV MMYQLGCYGG GTVLRIAKDI AENNKGARVL
AVCCDIMACL FRGPSDSDLE LLVGQAIFGD GAAAVIVGAE PDESVGERPI FELVSTGQTI
LPNSEGTIGG HIREAGLIFD LHKDVPMLIS NNIEKCLIEA FTPIGISDWN SIFWITHPGG
KAILDKVEEK LHLKSDKFVD SRHVLSEHGN MSSSTVLFVM DELRKRSLEE GKSTTGDGFE
WGVLFGFGPG LTVERVVVRS VPIKY