ID   A70A_DROMA              Reviewed;          55 AA.
AC   P67806; O18666;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   25-MAY-2022, entry version 36.
DE   RecName: Full=Accessory gland-specific peptide 70A;
DE   AltName: Full=Paragonial peptide B;
DE   AltName: Full=Sex peptide;
DE            Short=SP;
DE   Flags: Precursor;
GN   Name=Acp70A; Synonyms=PAPB;
OS   Drosophila mauritiana (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7226;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=9286679; DOI=10.1093/genetics/147.1.189;
RA   Cirera S., Aguade M.N.;
RT   "Evolutionary history of the sex-peptide (Acp70A) gene region in Drosophila
RT   melanogaster.";
RL   Genetics 147:189-197(1997).
CC   -!- FUNCTION: Represses female sexual receptivity and stimulates
CC       oviposition.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Main cells of the accessory glands of males
CC       (paragonial gland).
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DR   EMBL; X99412; CAA67789.1; -; Genomic_DNA.
DR   AlphaFoldDB; P67806; -.
DR   SMR; P67806; -.
DR   FlyBase; FBgn0021369; Dmau\Acp70A.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:InterPro.
DR   GO; GO:0046008; P:regulation of female receptivity, post-mating; IEA:InterPro.
DR   InterPro; IPR012608; Sex_peptide.
DR   Pfam; PF08138; Sex_peptide; 1.
PE   2: Evidence at transcript level;
KW   Behavior; Disulfide bond; Hydroxylation; Secreted; Signal.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000250"
FT   CHAIN           20..55
FT                   /note="Accessory gland-specific peptide 70A"
FT                   /id="PRO_0000020586"
FT   MOD_RES         28
FT                   /note="Hydroxyproline"
FT                   /evidence="ECO:0000250"
FT   MOD_RES         32
FT                   /note="Hydroxyproline"
FT                   /evidence="ECO:0000250"
FT   MOD_RES         34
FT                   /note="Hydroxyproline"
FT                   /evidence="ECO:0000250"
FT   MOD_RES         38
FT                   /note="Hydroxyproline"
FT                   /evidence="ECO:0000250"
FT   DISULFID        43..55
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   55 AA;  6424 MW;  E87397C3F196123D CRC64;
     MKTLSLFLVL VCLLGLVQSW EWPWNRKPTK YPIPSPNPRD KWCRLNLGPA WGGRC