ID   PL8L1_HUMAN             Reviewed;         177 AA.
AC   A1L4L8;
DT   04-DEC-2007, integrated into UniProtKB/Swiss-Prot.
DT   20-FEB-2007, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=PLAC8-like protein 1;
GN   Name=PLAC8L1;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA   Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA   Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA   Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA   Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA   Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA   Hunkapiller M.W., Myers E.W., Venter J.C.;
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SIMILARITY: Belongs to the cornifelin family. {ECO:0000305}.
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DR   EMBL; CH471062; EAW61851.1; -; Genomic_DNA.
DR   EMBL; BC130586; AAI30587.1; -; mRNA.
DR   EMBL; BC130588; AAI30589.1; -; mRNA.
DR   CCDS; CCDS34264.1; -.
DR   RefSeq; NP_001025040.1; NM_001029869.1.
DR   AlphaFoldDB; A1L4L8; -.
DR   BioGRID; 127518; 21.
DR   IntAct; A1L4L8; 1.
DR   MINT; A1L4L8; -.
DR   STRING; 9606.ENSP00000309087; -.
DR   BioMuta; PLAC8L1; -.
DR   PaxDb; A1L4L8; -.
DR   PeptideAtlas; A1L4L8; -.
DR   PRIDE; A1L4L8; -.
DR   Antibodypedia; 77009; 15 antibodies from 8 providers.
DR   DNASU; 153770; -.
DR   Ensembl; ENST00000311450.9; ENSP00000309087.4; ENSG00000173261.9.
DR   GeneID; 153770; -.
DR   KEGG; hsa:153770; -.
DR   MANE-Select; ENST00000311450.9; ENSP00000309087.4; NM_001029869.3; NP_001025040.1.
DR   UCSC; uc003lnv.4; human.
DR   CTD; 153770; -.
DR   DisGeNET; 153770; -.
DR   GeneCards; PLAC8L1; -.
DR   HGNC; HGNC:31746; PLAC8L1.
DR   HPA; ENSG00000173261; Tissue enriched (testis).
DR   neXtProt; NX_A1L4L8; -.
DR   OpenTargets; ENSG00000173261; -.
DR   PharmGKB; PA134890176; -.
DR   VEuPathDB; HostDB:ENSG00000173261; -.
DR   eggNOG; ENOG502S2DQ; Eukaryota.
DR   GeneTree; ENSGT00940000160864; -.
DR   HOGENOM; CLU_083147_3_0_1; -.
DR   InParanoid; A1L4L8; -.
DR   OMA; RSHAPAQ; -.
DR   OrthoDB; 1354725at2759; -.
DR   PhylomeDB; A1L4L8; -.
DR   TreeFam; TF330308; -.
DR   PathwayCommons; A1L4L8; -.
DR   SignaLink; A1L4L8; -.
DR   BioGRID-ORCS; 153770; 11 hits in 1071 CRISPR screens.
DR   ChiTaRS; PLAC8L1; human.
DR   GenomeRNAi; 153770; -.
DR   Pharos; A1L4L8; Tdark.
DR   PRO; PR:A1L4L8; -.
DR   Proteomes; UP000005640; Chromosome 5.
DR   RNAct; A1L4L8; protein.
DR   Bgee; ENSG00000173261; Expressed in sperm and 120 other tissues.
DR   ExpressionAtlas; A1L4L8; baseline and differential.
DR   Genevisible; A1L4L8; HS.
DR   InterPro; IPR006461; PLAC_motif_containing.
DR   PANTHER; PTHR15907; PTHR15907; 1.
DR   Pfam; PF04749; PLAC8; 1.
DR   TIGRFAMs; TIGR01571; A_thal_Cys_rich; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..177
FT                   /note="PLAC8-like protein 1"
FT                   /id="PRO_0000311396"
FT   VARIANT         11
FT                   /note="C -> S (in dbSNP:rs12187913)"
FT                   /id="VAR_037245"
SQ   SEQUENCE   177 AA;  19885 MW;  0BC4BE1E8CE7E76C CRC64;
     MNWFGSNFFR CPEDLSLLNI YSPLLSHMSS EDEHFISNLR GHVPASAVVK QPVRGASGRT
     TITAIVQTGG GWSTGLFSVC RDRRICFCGL FCPMCLECDI ARHYGECLCW PLLPGSTFAL
     RIGTRERHKI QGTLCEDWLA VHCCWAFSIC QVARELKMRT SQVYEICAVP MTKDTLV