ID   PLA2_ORYSI              Reviewed;         403 AA.
AC   A2WT96;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   31-MAY-2011, sequence version 2.
DT   25-MAY-2022, entry version 59.
DE   RecName: Full=Phospholipase A1-II 2;
DE            EC=3.1.1.-;
GN   ORFNames=OsI_03084;
OS   Oryza sativa subsp. indica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39946;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. 93-11;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
CC   -!- FUNCTION: Acylhydrolase that catalyzes the hydrolysis of phospholipids
CC       at the sn-1 position. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the AB hydrolase superfamily. Lipase family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EAY75192.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; CM000126; EAY75192.1; ALT_SEQ; Genomic_DNA.
DR   AlphaFoldDB; A2WT96; -.
DR   SMR; A2WT96; -.
DR   STRING; 39946.A2WT96; -.
DR   HOGENOM; CLU_018841_0_0_1; -.
DR   Proteomes; UP000007015; Chromosome 1.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0008970; F:phospholipase A1 activity; ISS:UniProtKB.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR002921; Fungal_lipase-like.
DR   InterPro; IPR033556; PLA.
DR   PANTHER; PTHR31828; PTHR31828; 1.
DR   Pfam; PF01764; Lipase_3; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
DR   PROSITE; PS00120; LIPASE_SER; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Hydrolase; Lipid degradation; Lipid metabolism;
KW   Reference proteome.
FT   CHAIN           1..403
FT                   /note="Phospholipase A1-II 2"
FT                   /id="PRO_0000409365"
FT   REGION          381..403
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   ACT_SITE        218
FT                   /note="Acyl-ester intermediate"
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        218
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU10037"
FT   ACT_SITE        286
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU10037"
FT   ACT_SITE        323
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU10037"
SQ   SEQUENCE   403 AA;  45054 MW;  CC8C15B382F28080 CRC64;
     MASRWRELHG SGHWDGLLDP LDVDLRRCLI TYGEMIMATY EAFIGEHRSP NAGMCRYRRA
     DLFRRVDVSH PGWYAATRYI YATANADVHG KVLLRPLCRE GRATECNWMG YVAVATDEGA
     AALGRRDIVV AWRGTQRALE WVADLKLAPA SAAGILGPEG ADGTDPSVHR GYLSLYTSED
     QCSELNKQSA RMQVLTEIAR LMDKYKDEET SITVIGHSLG ATLATLNAAD IAANSYNTSS
     LSPSGETRAP VTAVVFGSPR TGDRGFRDAF HRLRDLRMLR VRNRPDRIPH YPPVGYADVG
     VELLIDTRLS PFLRRHGSES QSHDLECHLH GVAGWHGDHR GFELVVDRDV ALVNKFDDCL
     ADEYPVPVRW KVHHNKSMVK GPDGRWVLQD HEPDDDDDDD DDD