ID   PLA6_ORYSJ              Reviewed;         411 AA.
AC   Q6F358; A0A0P0WR77; B9FIG0; Q0DFS3;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=Phospholipase A1-II 6;
DE            EC=3.1.1.-;
GN   OrderedLocusNames=Os05g0574000, LOC_Os05g49830;
GN   ORFNames=OJ1268_B08.3, OJ1735_C10.21, OsJ_19631;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16261349; DOI=10.1007/s00438-005-0039-y;
RA   Cheng C.-H., Chung M.C., Liu S.-M., Chen S.-K., Kao F.Y., Lin S.-J.,
RA   Hsiao S.-H., Tseng I.C., Hsing Y.-I.C., Wu H.-P., Chen C.-S., Shaw J.-F.,
RA   Wu J., Matsumoto T., Sasaki T., Chen H.-C., Chow T.-Y.;
RT   "A fine physical map of the rice chromosome 5.";
RL   Mol. Genet. Genomics 274:337-345(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
CC   -!- FUNCTION: Acylhydrolase that catalyzes the hydrolysis of phospholipids
CC       at the sn-1 position. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the AB hydrolase superfamily. Lipase family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAF18300.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=EEE64775.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AC098832; AAT69580.1; -; Genomic_DNA.
DR   EMBL; AC104284; AAU44110.1; -; Genomic_DNA.
DR   EMBL; AP008211; BAF18300.2; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP014961; BAS95455.1; -; Genomic_DNA.
DR   EMBL; CM000142; EEE64775.1; ALT_SEQ; Genomic_DNA.
DR   RefSeq; XP_015640670.1; XM_015785184.1.
DR   AlphaFoldDB; Q6F358; -.
DR   SMR; Q6F358; -.
DR   STRING; 4530.OS05T0574000-00; -.
DR   ESTHER; orysa-q6f358; Plant_phospholipase.
DR   PRIDE; Q6F358; -.
DR   EnsemblPlants; Os05t0574000-00; Os05t0574000-00; Os05g0574000.
DR   GeneID; 4339679; -.
DR   Gramene; Os05t0574000-00; Os05t0574000-00; Os05g0574000.
DR   KEGG; osa:4339679; -.
DR   eggNOG; KOG4569; Eukaryota.
DR   HOGENOM; CLU_018841_0_0_1; -.
DR   InParanoid; Q6F358; -.
DR   OMA; TWHNLEV; -.
DR   OrthoDB; 612344at2759; -.
DR   Proteomes; UP000000763; Chromosome 5.
DR   Proteomes; UP000007752; Chromosome 5.
DR   Proteomes; UP000059680; Chromosome 5.
DR   Genevisible; Q6F358; OS.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0008970; F:phospholipase A1 activity; ISS:UniProtKB.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR002921; Fungal_lipase-like.
DR   InterPro; IPR033556; PLA.
DR   PANTHER; PTHR31828; PTHR31828; 1.
DR   Pfam; PF01764; Lipase_3; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
DR   PROSITE; PS00120; LIPASE_SER; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Hydrolase; Lipid degradation; Lipid metabolism;
KW   Reference proteome.
FT   CHAIN           1..411
FT                   /note="Phospholipase A1-II 6"
FT                   /id="PRO_0000409371"
FT   ACT_SITE        226
FT                   /note="Acyl-ester intermediate"
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        226
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU10037"
FT   ACT_SITE        296
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU10037"
FT   ACT_SITE        334
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU10037"
SQ   SEQUENCE   411 AA;  45608 MW;  780C7A575A41959C CRC64;
     MSSQQWLGDG TARRWRELHG ESDWDGLLDP FDLDLRRTVI RYGEMAQATY DAFNHEKLSP
     HAGLSRFAAR RFFERAQLPG HSAAYRVARF VYATSCVAVP EPLILRSASR ARRCRESNWI
     GYVAVATDEG KAALGRRDIV VAWRGTVQSL EWIKDMDFVM VPPKGLLRDK ASDAMVHRGW
     LSMYTSRDSE SSHNKDSARD QVLSEVAKLV SMYQDEELSI TVTGHSLGAA LATLNAFDIV
     ENGYNRAPRA AAAAAGCPVT AFVFASPRVG GHGFKRRFDG ARGLGLRLLR VRNARDVVPR
     YPPAPPYHGV GTELAIDTGE SPYLRRPGNE LVWHNLECYL HGVAGARGGE AGRFKLAVER
     DVALANKSYG ALRDEHAVPA GWWIPSNRGM VRGADGRWTL MDREEDEDSA E