PLAT2_ARATH
ID PLAT2_ARATH Reviewed; 183 AA.
AC Q9SIE7; Q8LEG8;
DT 07-SEP-2016, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 25-MAY-2022, entry version 136.
DE RecName: Full=PLAT domain-containing protein 2 {ECO:0000305};
DE Short=AtPLAT2 {ECO:0000303|PubMed:25396746};
DE Short=PLAT domain protein 2 {ECO:0000303|PubMed:25396746};
DE Flags: Precursor;
GN Name=PLAT2 {ECO:0000303|PubMed:25396746};
GN OrderedLocusNames=At2g22170 {ECO:0000312|Araport:AT2G22170};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP INDUCTION, AND DISRUPTION PHENOTYPE.
RX PubMed=25396746; DOI=10.1371/journal.pone.0112946;
RA Hyun T.K., van der Graaff E., Albacete A., Eom S.H., Grosskinsky D.K.,
RA Boehm H., Janschek U., Rim Y., Ali W.W., Kim S.Y., Roitsch T.;
RT "The Arabidopsis PLAT domain protein1 is critically involved in abiotic
RT stress tolerance.";
RL PLoS ONE 9:E112946-E112946(2014).
CC -!- FUNCTION: Involved in response to abiotic stress.
CC {ECO:0000250|UniProtKB:O65660}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum
CC {ECO:0000250|UniProtKB:O65660}.
CC -!- INDUCTION: Down-regulated by salt stress.
CC {ECO:0000269|PubMed:25396746}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype under normal growth
CC conditions. {ECO:0000269|PubMed:25396746}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAM62648.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AC007168; AAD23623.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC07274.1; -; Genomic_DNA.
DR EMBL; BT002824; AAO22643.1; -; mRNA.
DR EMBL; BT004384; AAO42378.1; -; mRNA.
DR EMBL; AY085421; AAM62648.1; ALT_INIT; mRNA.
DR PIR; G84609; G84609.
DR RefSeq; NP_565527.1; NM_127785.4.
DR AlphaFoldDB; Q9SIE7; -.
DR SMR; Q9SIE7; -.
DR STRING; 3702.AT2G22170.1; -.
DR PaxDb; Q9SIE7; -.
DR PRIDE; Q9SIE7; -.
DR ProteomicsDB; 226200; -.
DR EnsemblPlants; AT2G22170.1; AT2G22170.1; AT2G22170.
DR GeneID; 816751; -.
DR Gramene; AT2G22170.1; AT2G22170.1; AT2G22170.
DR KEGG; ath:AT2G22170; -.
DR Araport; AT2G22170; -.
DR TAIR; locus:2060410; AT2G22170.
DR eggNOG; ENOG502RZE1; Eukaryota.
DR HOGENOM; CLU_092946_0_0_1; -.
DR InParanoid; Q9SIE7; -.
DR OMA; TAGVHAK; -.
DR OrthoDB; 1307023at2759; -.
DR PhylomeDB; Q9SIE7; -.
DR PRO; PR:Q9SIE7; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9SIE7; baseline and differential.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR GO; GO:0099503; C:secretory vesicle; HDA:TAIR.
DR GO; GO:0009579; C:thylakoid; HDA:TAIR.
DR GO; GO:0005773; C:vacuole; HDA:TAIR.
DR InterPro; IPR001024; PLAT/LH2_dom.
DR InterPro; IPR036392; PLAT/LH2_dom_sf.
DR Pfam; PF01477; PLAT; 1.
DR SUPFAM; SSF49723; SSF49723; 1.
DR PROSITE; PS50095; PLAT; 1.
PE 2: Evidence at transcript level;
KW Endoplasmic reticulum; Reference proteome; Signal; Stress response.
FT SIGNAL 1..25
FT /evidence="ECO:0000255"
FT CHAIN 26..183
FT /note="PLAT domain-containing protein 2"
FT /id="PRO_5006752344"
FT DOMAIN 31..158
FT /note="PLAT"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00152"
FT CONFLICT 36
FT /note="F -> Y (in Ref. 4; AAM62648)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 183 AA; 20130 MW; B0322292368BB92D CRC64;
MMPRRDVLFL SLLLVIATVS AVALADDEAD CVYTFFLRTG STFKAGTDSI ISARVYDKYG
DYIGIRNLEA WGGLMGPGYN YYERGNLDIF SGKAPCLPSP VCSLNLTSDG SGDHHGWYVN
YVEVTTAGVH AKCSYQSFDV EQWLASDTSP YELSAVRNNC PVSLRESVGR VGSEIRKTLS
WIV
