ID   PLBLD_DICDI             Reviewed;         569 AA.
AC   Q54PS7;
DT   01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Phospholipase B-like protein D;
DE            EC=3.1.1.-;
DE   Flags: Precursor;
GN   Name=plbD; ORFNames=DDB_G0284449;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: Probable phospholipase. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the phospholipase B-like family. {ECO:0000305}.
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DR   EMBL; AAFI02000064; EAL65273.1; -; Genomic_DNA.
DR   RefSeq; XP_638577.1; XM_633485.1.
DR   AlphaFoldDB; Q54PS7; -.
DR   SMR; Q54PS7; -.
DR   STRING; 44689.DDB0231379; -.
DR   PaxDb; Q54PS7; -.
DR   EnsemblProtists; EAL65273; EAL65273; DDB_G0284449.
DR   GeneID; 8624549; -.
DR   KEGG; ddi:DDB_G0284449; -.
DR   dictyBase; DDB_G0284449; plbD.
DR   eggNOG; KOG3774; Eukaryota.
DR   HOGENOM; CLU_027106_4_0_1; -.
DR   InParanoid; Q54PS7; -.
DR   OMA; LQIYYHY; -.
DR   PhylomeDB; Q54PS7; -.
DR   Reactome; R-DDI-1482788; Acyl chain remodelling of PC.
DR   Reactome; R-DDI-1482839; Acyl chain remodelling of PE.
DR   Reactome; R-DDI-1482922; Acyl chain remodelling of PI.
DR   Reactome; R-DDI-1483115; Hydrolysis of LPC.
DR   PRO; PR:Q54PS7; -.
DR   Proteomes; UP000002195; Chromosome 4.
DR   GO; GO:0005576; C:extracellular region; IBA:GO_Central.
DR   GO; GO:0004620; F:phospholipase activity; ISS:dictyBase.
DR   GO; GO:0046338; P:phosphatidylethanolamine catabolic process; ISS:dictyBase.
DR   GO; GO:0031161; P:phosphatidylinositol catabolic process; ISS:dictyBase.
DR   GO; GO:0009395; P:phospholipid catabolic process; ISS:dictyBase.
DR   InterPro; IPR007000; PLipase_B-like.
DR   PANTHER; PTHR12370; PTHR12370; 1.
DR   Pfam; PF04916; Phospholip_B; 1.
PE   3: Inferred from homology;
KW   Glycoprotein; Hydrolase; Lipid degradation; Lipid metabolism;
KW   Reference proteome; Secreted; Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..569
FT                   /note="Phospholipase B-like protein D"
FT                   /id="PRO_0000286120"
FT   CARBOHYD        93
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        126
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        181
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        425
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        430
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   569 AA;  66421 MW;  E5C8CE437B058030 CRC64;
     MIIFKNLLKL LIILLTIKLY FCIEIKREEH LTILNELNEN SDVIQYSILP GNNEEYEIVK
     GIQEDAIVYG YYMSNVEVNG WAYLSLVSND KYNDSTQSRA FGYLEGYLTK DLIWNSKVNY
     YKNAFNSSEI PNKLDDWLTE NIESIHTFIV NNRKSRYWNQ ITLVMDQING MLDGYNEANT
     NSSETLSLHD FFVLNMFGDL FDLMPALNLD KEYKYFQKDL NDIQDWFKRS QHCSALIKVS
     SDYSELYSGH TTWSGYYTML RIFKSYNQQF SSDVSGTLSK RNIFSSYPGA LISVDDFYLL
     GDTRMVVIET TNSLVTNDLY HLIRPTTVLS WMRVIVSNRM STNGKEWCEN FQRYNSGTYN
     NQWMIVSYNL FVPYNELKDG ALYVLEQIPG YIEFSDQTQA LRQGWWNSYN IPFYETIYDA
     SGYNNYTANN YSDSTIYYMS YQTCPRAEIF RNFAGYVESL EDFQSLLRYN DFEYDPLSHK
     LPFYAIASRY DLSKKNPSPF GATDTKVTCN SMIDQNTIVA ISGPTTSNGQ PIFEWNSKID
     FMESTSHLGC PEKYNFPWVS FSDTTFRNL