PLBLF_DICDI
ID PLBLF_DICDI Reviewed; 563 AA.
AC Q554H5; Q8T1G1;
DT 01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 02-MAY-2006, sequence version 1.
DT 25-MAY-2022, entry version 69.
DE RecName: Full=Phospholipase B-like protein F;
DE EC=3.1.1.-;
DE Flags: Precursor;
GN Name=plbF; ORFNames=DDB_G0275125;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=12097910; DOI=10.1038/nature00847;
RA Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA Noegel A.A.;
RT "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL Nature 418:79-85(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- FUNCTION: Probable phospholipase. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the phospholipase B-like family. {ECO:0000305}.
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DR EMBL; AAFI02000013; EAL69843.1; -; Genomic_DNA.
DR RefSeq; XP_643736.1; XM_638644.1.
DR AlphaFoldDB; Q554H5; -.
DR SMR; Q554H5; -.
DR STRING; 44689.DDB0231381; -.
DR PaxDb; Q554H5; -.
DR EnsemblProtists; EAL69843; EAL69843; DDB_G0275125.
DR GeneID; 8619779; -.
DR KEGG; ddi:DDB_G0275125; -.
DR dictyBase; DDB_G0275125; plbF.
DR eggNOG; KOG3774; Eukaryota.
DR HOGENOM; CLU_027106_4_0_1; -.
DR InParanoid; Q554H5; -.
DR OMA; EGYLTWS; -.
DR PhylomeDB; Q554H5; -.
DR PRO; PR:Q554H5; -.
DR Proteomes; UP000002195; Chromosome 2.
DR GO; GO:0005576; C:extracellular region; IBA:GO_Central.
DR GO; GO:0004620; F:phospholipase activity; ISS:dictyBase.
DR GO; GO:0046338; P:phosphatidylethanolamine catabolic process; ISS:dictyBase.
DR GO; GO:0031161; P:phosphatidylinositol catabolic process; ISS:dictyBase.
DR GO; GO:0009395; P:phospholipid catabolic process; ISS:dictyBase.
DR InterPro; IPR007000; PLipase_B-like.
DR PANTHER; PTHR12370; PTHR12370; 1.
DR Pfam; PF04916; Phospholip_B; 1.
PE 3: Inferred from homology;
KW Glycoprotein; Hydrolase; Lipid degradation; Lipid metabolism;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT CHAIN 22..563
FT /note="Phospholipase B-like protein F"
FT /id="PRO_0000286122"
FT CARBOHYD 85
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 107
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 118
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 121
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 208
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 312
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 537
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 563 AA; 64528 MW; F75DC01509AF660A CRC64;
MKIINSFVFI FVLLFVFNTN AIKLSEDEKY SIEEKPEWYS IDSNFAVSPG KISDALGWGY
YKNEILKDGW GKLYVEMNKF MTPENSSIYY EATGYLEGYL TWSTTWNYSQ AYFQNYMNGT
NESDIPTPLV EFLKINYDWM TSTFSNRDES VYDTQVSNVI YQFEGFARGY QQAADSDKQL
TTLQLLLLQY AGDLEDVAGY LEYEMAQNKT EYINRVKSLK EIETLFAVKG RCSGLVRITP
DYGELFISHT TWGSYFTAGY RIFKRIIIPD PTVPGNEILF ASYAGVLTSD DDFFMIPSTE
MVIIETTNDI LNTSLYQYVT PNSLLYFVRS IIANRLSNTA QEWTNNFIQY NSGTYSNQWM
IVDYKLFTPY QPLQPNTFWI IEQLPGGFMS ADMTEVLALG NWPSFNRPFF PEIYDAMGYS
YYEKLYGDII SYDLNPRSKM FRRDVPNVMS LDGMQQIMTQ NNYKSDPFSG GFPGNAIAAR
YDLGGGPAEP LSWSFIGLHG AIDSKITSYS LLQQNQAIAI NGMTVTPDCP PFTWNSNWST
VSAHYGSPET FDFDWISITI TDK
