ID   ASTE1_PONAB             Reviewed;         679 AA.
AC   Q5RCY5;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 48.
DE   RecName: Full=Protein asteroid homolog 1;
GN   Name=ASTE1;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Heart;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Possible role in EGF receptor signaling. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the asteroid family. {ECO:0000305}.
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DR   EMBL; CR858133; CAH90372.1; -; mRNA.
DR   RefSeq; NP_001125181.1; NM_001131709.1.
DR   AlphaFoldDB; Q5RCY5; -.
DR   STRING; 9601.ENSPPYP00000015774; -.
DR   GeneID; 100172070; -.
DR   KEGG; pon:100172070; -.
DR   CTD; 28990; -.
DR   eggNOG; ENOG502QQRA; Eukaryota.
DR   InParanoid; Q5RCY5; -.
DR   OrthoDB; 966573at2759; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0004518; F:nuclease activity; IEA:InterPro.
DR   InterPro; IPR026832; Asteroid.
DR   InterPro; IPR039436; Asteroid_dom.
DR   InterPro; IPR029060; PIN-like_dom_sf.
DR   InterPro; IPR006085; XPG_DNA_repair_N.
DR   PANTHER; PTHR15665; PTHR15665; 1.
DR   Pfam; PF12813; XPG_I_2; 1.
DR   Pfam; PF00752; XPG_N; 1.
DR   SUPFAM; SSF88723; SSF88723; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..679
FT                   /note="Protein asteroid homolog 1"
FT                   /id="PRO_0000310460"
FT   REGION          625..645
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   679 AA;  77104 MW;  D135858C57B65EF2 CRC64;
     MGIRGLMSFV EDHSNEFFTD LKLRDTKIVI DGYALFHRLC FSSNLDLRYG GDYDSFADVV
     QKFFESLFAC NICPYVVLDG GCDISDKKLT TLKDRAREKI QMAHSLSVGG SGYVCPLLIR
     EVFIQVLIKL RVCFVQCFSE ADRDIMTLAN HWNCPVLSSD SDFCIFDLKT GFCPLNSFQW
     RNMDTIKGTQ NYIPAKCFSL DAFCHHFSNM NKALLPLFAV LCGNDHVNLP IMETFLSKAR
     LPLGATSSKG RRHHRILGLL NWLSHFANPT EALDNVLKYL PKKDRENVKE LLCCSMEEYQ
     QSQVKLQDFF QCGTYVCPDA LNLGLPEWVL VALAKGQLSP FISDALVLRR TILPTQVENM
     QQPNAHRISQ PIRQIIYGLL LNASPHLDKT SWNALPPQPL AFSEVERINK NIRTSIIDAV
     ELAKDHSDLS RLTELSLRRR QMLLLETLKV KQTILEPIPT SLKLPIAVSC YWLQHTETKA
     KLHHLQSLLL TMLVGPLIAI INSPGKEELQ EDGAKMLYAE FQRVKAQTRL GTRLDLDTAH
     IFCQWQSCLQ MGMYLNQLLP TPLPEPDLTR LYSGSLVHGL CQQLLASTSV ESLLSICPEA
     KQLYEYLFNA TRSYAPAEIF LPKGRSNSKK KRQKKQNTSC SKNRGRTTAH TKCWYEGNNR
     FGLLMVENLE EHSEASNIE