PLH26_FORAG
ID PLH26_FORAG Reviewed; 990 AA.
AC T2KM18;
DT 16-OCT-2019, integrated into UniProtKB/Swiss-Prot.
DT 13-NOV-2013, sequence version 1.
DT 25-MAY-2022, entry version 37.
DE RecName: Full=TonB-dependent receptor P26 {ECO:0000303|PubMed:31285597};
DE Short=P26_TBDR {ECO:0000303|PubMed:31285597};
DE AltName: Full=Polysaccharide utilization locus H protein P26 {ECO:0000303|PubMed:31285597};
DE Short=PUL H protein P26;
GN ORFNames=BN863_22150;
OS Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 /
OS M-2Alg 35-1).
OC Bacteria; Bacteroidetes; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Formosa.
OX NCBI_TaxID=1347342;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1;
RX PubMed=23995932; DOI=10.1128/aem.01937-13;
RA Mann A.J., Hahnke R.L., Huang S., Werner J., Xing P., Barbeyron T.,
RA Huettel B., Stueber K., Reinhardt R., Harder J., Gloeckner F.O.,
RA Amann R.I., Teeling H.;
RT "The genome of the alga-associated marine flavobacterium Formosa agariphila
RT KMM 3901T reveals a broad potential for degradation of algal
RT polysaccharides.";
RL Appl. Environ. Microbiol. 79:6813-6822(2013).
RN [2]
RP FUNCTION, SUBCELLULAR LOCATION, AND INDUCTION.
RX PubMed=31285597; DOI=10.1038/s41589-019-0311-9;
RA Reisky L., Prechoux A., Zuehlke M.K., Baeumgen M., Robb C.S., Gerlach N.,
RA Roret T., Stanetty C., Larocque R., Michel G., Song T., Markert S.,
RA Unfried F., Mihovilovic M.D., Trautwein-Schult A., Becher D., Schweder T.,
RA Bornscheuer U.T., Hehemann J.H.;
RT "A marine bacterial enzymatic cascade degrades the algal polysaccharide
RT ulvan.";
RL Nat. Chem. Biol. 15:803-812(2019).
CC -!- FUNCTION: TonB-dependent receptor probably involved in ulvan
CC degradation (Probable). Ulvan is the main polysaccharide component of
CC the Ulvales (green seaweed) cell wall. It is composed of disaccharide
CC building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-
CC glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl)
CC (Probable). The TonB-dependent receptor may mediate transport of ulvan
CC oligosaccharides from the surface of the outer membrane to the
CC periplasm for subsequent degradation (By similarity).
CC {ECO:0000250|UniProtKB:Q8A1G2, ECO:0000305|PubMed:31285597}.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane
CC {ECO:0000269|PubMed:31285597}; Multi-pass membrane protein
CC {ECO:0000250|UniProtKB:Q8A1G2}.
CC -!- INDUCTION: By ulvan and rhamnose. {ECO:0000269|PubMed:31285597}.
CC -!- SIMILARITY: Belongs to the TonB-dependent receptor family.
CC {ECO:0000305}.
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DR EMBL; HG315671; CDF79927.1; -; Genomic_DNA.
DR AlphaFoldDB; T2KM18; -.
DR SMR; T2KM18; -.
DR STRING; 1347342.BN863_22150; -.
DR EnsemblBacteria; CDF79927; CDF79927; BN863_22150.
DR PATRIC; fig|1347342.6.peg.2222; -.
DR eggNOG; COG1629; Bacteria.
DR HOGENOM; CLU_004317_0_2_10; -.
DR OMA; IRANITH; -.
DR Proteomes; UP000016160; Chromosome.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.170.130.10; -; 1.
DR Gene3D; 2.40.170.20; -; 1.
DR InterPro; IPR008969; CarboxyPept-like_regulatory.
DR InterPro; IPR012910; Plug_dom.
DR InterPro; IPR037066; Plug_dom_sf.
DR InterPro; IPR023996; TonB-dep_OMP_SusC/RagA.
DR InterPro; IPR023997; TonB-dep_OMP_SusC/RagA_CS.
DR InterPro; IPR000531; TonB-dep_rcpt_b-brl.
DR InterPro; IPR036942; TonB_rcpt_b-brl_sf.
DR Pfam; PF07715; Plug; 1.
DR Pfam; PF00593; TonB_dep_Rec; 1.
DR SUPFAM; SSF49464; SSF49464; 1.
DR TIGRFAMs; TIGR04056; OMP_RagA_SusC; 1.
DR TIGRFAMs; TIGR04057; SusC_RagA_signa; 1.
PE 2: Evidence at transcript level;
KW Cell outer membrane; Membrane; Receptor; Reference proteome; TonB box;
KW Transmembrane; Transmembrane beta strand.
FT CHAIN 1..990
FT /note="TonB-dependent receptor P26"
FT /id="PRO_0000448315"
FT REGION 878..902
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 86..93
FT /note="TonB box"
FT /evidence="ECO:0000255"
FT MOTIF 974..990
FT /note="TonB C-terminal box"
FT /evidence="ECO:0000255"
FT COMPBIAS 888..902
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 990 AA; 107920 MW; B3BFCF50A542FFB5 CRC64;
MFCYSSLHAQ IISGTVSAEG QVLPGAAVII KGSTKGTSTD FDGYYTIEAQ ASDVLVFSYV
GYANKEVTVG TNTQIDVALE ADNTLDEVVV IGYGTQRKSD LTGSVSSVSA EDVNVNPVSR
VDQALQGRAA GVQVTQTSGA PGAASVIRVR GGNSITGSNE PLWVIDGIVV GTNFNLNNIN
SNDIKSIEIL KDASSIAIYG SRGANGVVLV TTKTGTGAGS SKPEVSANIY TSMQMVPELP
KMLSQAEQIA YTNESAAFRG AAIPFPNDPS TYPNNDWFDL LLGPAPIYNA DVSITGASEN
VSYYTSLNYF NQEGIVKTSG IEKYIFRSNL DIRLSDKLKT GFRVNYSYID QQNGLVGYGN
AIATLPTQPI YNEDGSYNGF DEVVGSPWSN PIANMALNTN ETFRNNFLGS FYIDYSPSEK
WIIRSTFSPD FDNSKQNRFT SSQSPNLLYL GEGGNASVRT VNTKGWNNEN TIQYQSEIGE
NHRITALGGA SFQKVSTEIV ESEAFGITND ATGFNNLSNS DPTRNILTSD YSGFQIASFF
GRLNYAYKDK YLLTLVGRTD GSSVFSDDNK YEFYPSIAAA WKISEEGFMQ NQETFGELKL
RASYGKSGNQ AIDPYRTKGL LVEANTTLNG IQQTGLTLGR PSNPNLTWET TNSLDIALEA
SMFNGRVFAE LNYYYKKTND LLLDVTIPKQ TGFNSQLQNV GSLENKGWEF SLNTTNVRTD
NFNWKSTLML SSNKNKILDL GGVDFIDLVV DELLGSGNTR LIVGESVPVF TGVKFLGTWK
SQEEIDASGL RDPQVVGGAK YHDENGDGII STDDAVVLGS PLPDLIFGFE NTLSYKNLDF
SFYFQGTQGN EVYNLRMRNH YFNRGEFTKF AEVADRWTPE NPTSDIPRAG GDSVTGTPPN
SAYVEDGSHI RLKTVRLAYN MPVDKMGMDG VKNATVYLTG TNLLLWSDFR LIDPEGSNFG
RNGIGNIAQG YNDGSYPNPR TITLGLNVTF
