PLH3_FORAG
ID PLH3_FORAG Reviewed; 1001 AA.
AC T2KPJ3;
DT 16-OCT-2019, integrated into UniProtKB/Swiss-Prot.
DT 13-NOV-2013, sequence version 1.
DT 25-MAY-2022, entry version 37.
DE RecName: Full=TonB-dependent receptor P3 {ECO:0000303|PubMed:31285597};
DE Short=P3_TBDR {ECO:0000303|PubMed:31285597};
DE AltName: Full=Polysaccharide utilization locus H protein P3 {ECO:0000303|PubMed:31285597};
DE Short=PUL H protein P3;
DE Flags: Precursor;
GN ORFNames=BN863_21920;
OS Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 /
OS M-2Alg 35-1).
OC Bacteria; Bacteroidetes; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Formosa.
OX NCBI_TaxID=1347342;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1;
RX PubMed=23995932; DOI=10.1128/aem.01937-13;
RA Mann A.J., Hahnke R.L., Huang S., Werner J., Xing P., Barbeyron T.,
RA Huettel B., Stueber K., Reinhardt R., Harder J., Gloeckner F.O.,
RA Amann R.I., Teeling H.;
RT "The genome of the alga-associated marine flavobacterium Formosa agariphila
RT KMM 3901T reveals a broad potential for degradation of algal
RT polysaccharides.";
RL Appl. Environ. Microbiol. 79:6813-6822(2013).
RN [2]
RP FUNCTION, AND INDUCTION.
RX PubMed=31285597; DOI=10.1038/s41589-019-0311-9;
RA Reisky L., Prechoux A., Zuehlke M.K., Baeumgen M., Robb C.S., Gerlach N.,
RA Roret T., Stanetty C., Larocque R., Michel G., Song T., Markert S.,
RA Unfried F., Mihovilovic M.D., Trautwein-Schult A., Becher D., Schweder T.,
RA Bornscheuer U.T., Hehemann J.H.;
RT "A marine bacterial enzymatic cascade degrades the algal polysaccharide
RT ulvan.";
RL Nat. Chem. Biol. 15:803-812(2019).
CC -!- FUNCTION: TonB-dependent receptor probably involved in ulvan
CC degradation (Probable). Ulvan is the main polysaccharide component of
CC the Ulvales (green seaweed) cell wall. It is composed of disaccharide
CC building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-
CC glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl)
CC (Probable). The TonB-dependent receptor may mediate transport of ulvan
CC oligosaccharides from the surface of the outer membrane to the
CC periplasm for subsequent degradation (By similarity).
CC {ECO:0000250|UniProtKB:Q8A1G2, ECO:0000305|PubMed:31285597}.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane
CC {ECO:0000250|UniProtKB:Q8A1G2}; Multi-pass membrane protein
CC {ECO:0000250|UniProtKB:Q8A1G2}.
CC -!- INDUCTION: By ulvan and rhamnose. {ECO:0000269|PubMed:31285597}.
CC -!- SIMILARITY: Belongs to the TonB-dependent receptor family.
CC {ECO:0000305}.
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DR EMBL; HG315671; CDF79904.1; -; Genomic_DNA.
DR RefSeq; WP_038530480.1; NZ_HG315671.1.
DR AlphaFoldDB; T2KPJ3; -.
DR SMR; T2KPJ3; -.
DR STRING; 1347342.BN863_21920; -.
DR EnsemblBacteria; CDF79904; CDF79904; BN863_21920.
DR PATRIC; fig|1347342.6.peg.2199; -.
DR eggNOG; COG4771; Bacteria.
DR HOGENOM; CLU_004317_0_2_10; -.
DR OMA; ANDDLTW; -.
DR OrthoDB; 71288at2; -.
DR Proteomes; UP000016160; Chromosome.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.170.130.10; -; 1.
DR Gene3D; 2.40.170.20; -; 1.
DR InterPro; IPR008969; CarboxyPept-like_regulatory.
DR InterPro; IPR012910; Plug_dom.
DR InterPro; IPR037066; Plug_dom_sf.
DR InterPro; IPR023996; TonB-dep_OMP_SusC/RagA.
DR InterPro; IPR023997; TonB-dep_OMP_SusC/RagA_CS.
DR InterPro; IPR000531; TonB-dep_rcpt_b-brl.
DR InterPro; IPR036942; TonB_rcpt_b-brl_sf.
DR Pfam; PF07715; Plug; 1.
DR Pfam; PF00593; TonB_dep_Rec; 1.
DR SUPFAM; SSF49464; SSF49464; 1.
DR TIGRFAMs; TIGR04056; OMP_RagA_SusC; 1.
DR TIGRFAMs; TIGR04057; SusC_RagA_signa; 1.
PE 2: Evidence at transcript level;
KW Cell outer membrane; Membrane; Receptor; Reference proteome; Signal;
KW TonB box; Transmembrane; Transmembrane beta strand.
FT SIGNAL 1..26
FT /evidence="ECO:0000255"
FT CHAIN 27..1001
FT /note="TonB-dependent receptor P3"
FT /id="PRO_5004602761"
FT MOTIF 109..116
FT /note="TonB box"
FT /evidence="ECO:0000255"
FT MOTIF 984..1001
FT /note="TonB C-terminal box"
FT /evidence="ECO:0000255"
SQ SEQUENCE 1001 AA; 109272 MW; FF33747DE549D3E5 CRC64;
MTTKNNKQLK SVLFMFLLLI GAYVKAQEKN VSGTVTSSED GMMLPGVNII VKGTASGTTS
DFDGNYNIEV PDSNAILQFN YLGFVTQEIK VGAQTNISVV LQVDQNELEE IVVIGYGTVK
KSDVSGSVSS VKSAELTAYP TVSAEQALQG RAAGVQVQSN NGGEPGAPIK VRIRGGTSIN
ASSDALIVVD GFVGASMPAP QDIASMEVLK DASATAIYGS RGANGVIMVT TKKGTSSKPT
LELNTSYSLQ HVNNTIDLLD ADEFATYRQA YSENYVQGPA NTDWQDEIYT TGSISNTQLA
FSGGSDNSKY YISGNYFAQD GVVINSNLER FTILSNVDVD ITKRFKVGLN VFGGRSTKDG
VSTQAQTGGT GGGDVISSAY RFAPDLGIYN ADGTYTINSL GDDIDNPYAL ATESVDERKA
DTYRANFYAA YEFIDGLEFK TTFGFSSENT QIGKFKPTTI LAGAGVGGEA TFEYRNTTNT
LSENYLTYNK SFGAHNLSLL GGYSYQKVQN EGAFAGARSF VTNEVSYRNL EGGAVTMQPS
SYLNETELVS VFGRVNYEYA SKYIFTFTAR RDGSSNFSKN NKYAFFPSGA IAWNMAKENF
LKDSNTITTW KWRASYGATG NPSISPYETL AKFSSVYAVV GDQQVNGVVL TDFANDNLKW
ETSKQLDLGL DVALFDNRLE LSFDYYTIKT EDLLFPRPLP EYSGVSSQIQ NIGELENKGY
EFSINSRNIT NQDFTWSTAF NFSRNKNKMV KLPDGDDLFI DSAPGHFLQR QTQILREGEA
IGSFYGYEYK GVYQGGNFPE GTATLSGDSD PGGELFADLD GNGEISTADR KIIGDPTPDF
TMGFNNDLRY KNFDMNLFFQ ASVGGEILNY TLLELGSGAA NSTADMVNAW SPTNTNTDVP
RPAVREKRIT SRYVYDGSYV RLKNLSFGYN LPESFLGKTG LQTVRLYVSG QNLLTFTDYP
GADPEANYRN DNNQRSNTNI GLDYGSYPNV RTFTMGLNMK F
